Microbulbifer sp. SH-1: GNX18_00390
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Entry
GNX18_00390 CDS
T10373
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
micl Microbulbifer sp. SH-1
Pathway
micl00300
Lysine biosynthesis
micl00550
Peptidoglycan biosynthesis
micl01100
Metabolic pathways
micl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
micl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GNX18_00390 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GNX18_00390 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GNX18_00390 (murF)
Enzymes [BR:
micl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GNX18_00390 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PRK
tRNA_lig_kinase
Motif
Other DBs
NCBI-ProteinID:
QIL88397
UniProt:
A0A6G8D9M4
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Position
72154..73524
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AA seq
456 aa
AA seq
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MIAPISLQQLQQRFGGELINGSVSFTAVCTDTRKLDPGALFVALRGETFDAHDFLADIDG
NALGVVTEKVIEGSSLPQWLVADTTIALGQIGRLCREQFNGPVIGITGSCGKTTVKEMLA
SIFGQSHRVCVTRGNLNNHFGVPMTLFSLAPEHQVLIVEMGASGPNEIGYLCGIARPGIT
AVNNVMPAHVEGFGSVDGIATAKGQIYTSLEPGAIAVLNADDNYADYWRGEMPEGVHTLE
VGLGHQCAVHADNIVIDALGCASFDLVVEGVSHPVQLQLLGEHNVHNALVAAGCAYAAGI
PVAEIATGLSALSGVGGRMQSVVGKRGATVIDDSYNANPGSVSAAIELLAQRDGKKILVL
GDMAELGPEADKAHRDMGRLARERGIDQLFTLGTLSAAASIEFAAGRQHVQKNFSEREAL
IQALAPELDGNTTVLVKGSRSARMELVVQALTNGNQ
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcccccatttccctgcagcaattacagcagcgtttcggcggtgagctgattaac
ggctcggtgtcgtttaccgccgtgtgtaccgacacccgcaagctggacccgggcgcgctg
tttgtggcgctgcggggggaaactttcgatgcgcacgattttcttgctgacatcgacggc
aatgcgctgggcgtggtgacggaaaaagtgattgagggctcgtccctgccgcagtggctg
gtggctgacaccaccattgccctggggcagatcggccgtctgtgtcgcgaacaatttaac
ggtccggtgatcggcattaccggttcctgtggcaagaccacggtgaaagaaatgctggcg
tcgattttcggccagagccaccgggtatgtgtgacccgcggcaacctgaacaaccatttc
ggggtgcccatgaccctgttttccctcgcgccggaacaccaggtgctgatcgtggaaatg
ggcgcgagcgggccgaatgaaatcggctacctgtgcggcatcgccaggccgggaattacc
gcggtcaacaacgtgatgccagcacatgtggagggctttggctcagtggatggcatcgcc
accgccaaggggcagatctacaccagcctcgagcccggtgccattgcggtgctgaacgcg
gacgacaactacgcagattactggcgcggcgaaatgccggaaggtgtgcacaccctggaa
gttggtttaggtcaccagtgcgccgtgcatgcggacaacattgtaatagacgcattgggc
tgcgcgtccttcgatctggtggtggaaggcgtaagccacccggtgcagctgcaactgctc
ggcgagcacaacgtgcacaacgcactggtcgccgccggctgcgcctatgcggcgggaata
ccggttgcggaaattgccaccggactcagcgcgctgtcgggcgttggcggtcgcatgcag
tccgtcgtaggtaaacgcggcgcgacggtgatcgacgacagctacaacgccaacccgggt
tctgtcagcgctgccatcgaactgctggcgcagcgcgatggcaagaagatcctggtgctg
ggagatatggcggagctggggccggaggcggacaaggcgcaccgcgatatgggccggctg
gcgcgggagcggggcatcgatcaactgtttaccctcggcactctgagtgctgcggcgagt
attgaatttgccgcgggtcggcaacacgttcaaaagaatttttccgagcgcgaggccttg
atccaggcactggcgccggaactggatgggaacaccactgtgctggtgaaaggttcccgc
agtgcgcgcatggaactggtcgtgcaggcactcaccaacgggaatcaataa
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