Mycobacterium intracellulare subsp. intracellulare: MIP_00721
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Entry
MIP_00721 CDS
T02325
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mid
Mycobacterium intracellulare subsp. intracellulare
Pathway
mid00290
Valine, leucine and isoleucine biosynthesis
mid00620
Pyruvate metabolism
mid01100
Metabolic pathways
mid01110
Biosynthesis of secondary metabolites
mid01210
2-Oxocarboxylic acid metabolism
mid01230
Biosynthesis of amino acids
Module
mid_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mid00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MIP_00721
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MIP_00721
Enzymes [BR:
mid01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MIP_00721
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AFS12491
UniProt:
J9WB28
LinkDB
All DBs
Position
complement(530198..532168)
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AA seq
656 aa
AA seq
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MTSNSDAFSSTRSIVKPAGPPGPGQPAWNPQRGSSMPVSRYRPFAEEVEPIRLADRTWPD
RVITSAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFV
REIITDGAIPDDVTIQVLTQCRPELIERTFEACQGAPQAIVHFYNSTSILQRRVVFRAEK
AAVQDIATAGARKCVEEAAKYPGTRWRFEYSPESYTGTELEYAKQVCDAVGEIIGPTPEN
PIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYQAGA
DRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHP
YGGDLVYTAFSGSHQDAINKGLDQMKVDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAV
IRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSQVVQKITDGEGGEVSPKEMWDAFSEEY
LAPVWPLERVKQRVDASEEDSGVTSIAATVKINGVETEISGSGNGPLAAFVHALGDVGFD
VAVLDYSEHAMSSGDDAQAAAYVEASVSIASAAEPGEAGRHPSDPVSIASAAEPGEAGRH
PSGPVSIASAAEPGEAGRHPSGPVGARTVWGVGIAPSITTASLRAVVSAVNRAARA
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
gtgacttccaattccgacgcattcagctcgacacgcagcatcgtcaaacccgcgggcccg
ccggggcccgggcagcccgcatggaacccccagcgcggctcgtcgatgccggtcagccgg
taccggcccttcgccgaagaggtcgagccgatccggctcgccgatcgcacctggcccgac
cgggtcatcaccagcgcgccgctgtggtgcgcggtggacctgcgcgacggcaaccaggcg
ctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgatctgctggtccgcatg
ggctacaaggagatcgaggtcgggttcccgtcggccagccaaaccgacttcgacttcgtc
cgcgagatcatcaccgacggcgccatccccgacgacgtcaccatccaggtgctgacccag
tgccggccggaactgatcgagcgcacgttcgaggcgtgccagggcgcgccgcaggccatc
gtgcacttctacaactcgacgtcaatcctgcagcgccgcgtcgtatttcgcgccgagaag
gccgcggtgcaagacatcgcgaccgcgggcgcccgcaagtgcgtcgaggaggccgccaag
tacccgggcacgcggtggcggttcgagtattcgccggagtcctacaccggaaccgagctg
gagtacgccaagcaggtgtgcgacgccgtcggcgaaatcatcgggcccacaccggaaaac
ccgatcatcttcaacctgcccgccaccgtggagatggccaccccgaacgtctacgccgat
tcgatcgagtggatgagccgcaacctggccaaccgggaatcggtcatcctgagcctgcat
cctcacaacgaccgcggaaccgccgttgccgcagcggaattgggctaccaggcgggtgcc
gaccggatcgagggctgcctgttcggcaacggtgagcgcaccggcaacgtctgcctggtg
acgctggggctgaacctgttctcgcgcggcgtggacccgcagatcgacttctccaacatc
gacgagatccgccgcacggtggagtactgcaaccagctgccggtccacgagcgccacccc
tacggcggtgacctggtctacaccgcgttctccggtagccaccaggacgccatcaacaag
ggcctggaccagatgaaggtcgacgcggatgccgcggacaccgacgtcgaggacatgctc
tggcaggtgccgtatctgccgatcgaccccaaggatgtcgggcgcacctacgaggcggtg
atccgggtcaactcgcagtccggcaagggcggggtggcctacatcatgaaggccgatcac
ggcctggccctgccgcggcggctgcagatcgagttctcccaggtggtgcagaagatcacc
gacggcgagggcggcgaggtctcgccgaaggagatgtgggacgcgttctccgaggagtat
ctggccccggtgtggccgctggagcgggtgaagcagcgggtcgacgcttcggaggaggac
agcggcgtcaccagcatcgccgcgaccgtcaagatcaacggggtggagaccgagatcagt
gggtccggcaacggcccgctggccgcgttcgtccacgcgctgggcgatgtcggattcgac
gtggccgtgctggattactccgagcacgcgatgagttccggtgacgacgcgcaggccgcg
gcctacgtggaggcgtcggtgtcgatcgcgagcgcggcggagccgggcgaagcgggtcgg
cacccatcggatccggtgtcgatcgcgagcgcggcggagccgggcgaagcgggtcggcac
ccatcaggcccggtgtcgatcgcgagcgcggcggagccgggcgaagcgggtcggcaccca
tcgggtccggtgggcgctcgcacggtgtggggtgtcggcatcgcgccgtcgatcaccaca
gcgtcgctgcgtgcggtcgtgtcggcggtcaaccgcgcggctcgcgcctga
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