Mycobacterium intracellulare subsp. intracellulare: MIP_02457
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Entry
MIP_02457 CDS
T02325
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mid
Mycobacterium intracellulare subsp. intracellulare
Pathway
mid00280
Valine, leucine and isoleucine degradation
mid00640
Propanoate metabolism
mid00785
Lipoic acid metabolism
mid01100
Metabolic pathways
mid01110
Biosynthesis of secondary metabolites
mid01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mid00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MIP_02457
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MIP_02457
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MIP_02457
Enzymes [BR:
mid01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MIP_02457
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
DUF4219
Motif
Other DBs
NCBI-ProteinID:
AFS13682
UniProt:
J9WGT9
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All DBs
Position
1776870..1777961
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AA seq
363 aa
AA seq
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MAQMSSMPMAVDLEPVQLVAADGSPSPERRYGRDLPAETLSWLYELMVITRELDAEFVNL
KRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYRELGAFLVRGIPPGHVGAVWRGTW
HGGLEFTKKCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTLAFLGDGATSTGDVHEALN
FAAVFTTPCVFLVQNNQWAISTPIHKQTAAPSLAHKAIGYGMPGVRVDGNDVLACYAVTA
EAAARARAGGGPTLIEAITYRMGPHTTSDDPSRYRTQDEVDHWAALDPIARYRSYLRAQG
LWSERLEERVIGRAQRMRTELRDAVVDAPDFDIDEVFTSVYAEITPGLQAQRQQLRAELD
RSD
NT seq
1092 nt
NT seq
+upstream
nt +downstream
nt
gtggcgcagatgtcttcgatgcccatggcggtcgacctcgaaccggtccaactcgtggcc
gccgatggctcgccgtcacccgaacgccgttacggccgcgaccttcccgcggagacgctg
agctggctctacgagctgatggtgatcacccgggaactcgacgccgaattcgtgaacctc
aagcgccaaggcgaactggcgctctttgcgtcgtgccgcggtcaggaagccgcccagatc
ggtgcggcggcgtgcctgcgcaaaaccgactggttgttccctcaatatcgcgagctgggc
gcctttttggtgcgcggcatcccgcccgggcacgtcggggccgtgtggcgcggaacctgg
catggcggcctggaattcaccaagaagtgctgcgccccgctctcgattccgatcggcacc
cagaccctgcacgccgtgggcgccgcgatggccgcgcaacggctgggcgaagattcggtg
acgctggcctttctcggtgacggagccaccagcacaggagacgtgcacgaggcgctgaac
ttcgccgccgtgttcaccacgccctgcgtgttcctcgtgcagaacaaccagtgggcgatc
tcgacgccgatccacaaacagaccgccgcaccgtcgctggcgcacaaggcgattggctac
ggcatgcccggagtccgggtagatggcaatgacgtcttggcctgctacgccgtgacggcc
gaggccgccgcccgtgcccgcgccggcggcggcccgacattgatcgaggcgatcacctac
cggatgggcccacacaccacctccgatgacccgagtcgataccggacgcaggacgaggtc
gatcactgggcggcgctggacccgatcgcgcggtaccgctcctacctgcgggcccagggc
ctgtggtcggaacgcttggaggaacgggtcattggccgcgcacagcggatgcgcaccgaa
ttgcgcgacgcggtggtcgatgcgcccgatttcgacatcgacgaggtgttcacctcggtg
tacgccgaaatcacgccgggactgcaggcacagcgacagcagcttcgggccgaactcgac
cgaagcgattga
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