Mycobacterium intracellulare subsp. intracellulare: MIP_03221
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Entry
MIP_03221 CDS
T02325
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alaninligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mid
Mycobacterium intracellulare subsp. intracellulare
Pathway
mid00300
Lysine biosynthesis
mid00550
Peptidoglycan biosynthesis
mid01100
Metabolic pathways
mid01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mid00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MIP_03221
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MIP_03221
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MIP_03221
Enzymes [BR:
mid01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MIP_03221
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AFS14215
UniProt:
J9WB16
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Position
2365648..2367195
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AA seq
515 aa
AA seq
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MIELTVAEIADIVGGTLADISPQDAARRRVTGTVEFDSRAVGPGGLFLALPGARSDGHDH
AGAAIAAGAVAVLAARPVGVPAVVVAPAAASGSRAGVLEHDPDGSGAAVLAALAKLAQVV
AAELVAGGLRIVGITGSSGKTSTKDLVAAVLKPLGEVVAPPGSFNNELGHPWTVLRATPE
TDFLVLEMSARHPGNIAALAEIAPPAIGVVLNVGTAHLGEFGSREAIAQTKSELPQSVPA
SGVVILNADDPAVAAMAGVTAARVVRVSRAENTSAGPSQLWAGPVSLDEVARPCFTLHHR
DTSGTTQAQVRLGVYGDHQVTNALCAAAVALECGADVDQVAAALAGAGPVSRHRMHVTTR
ADGVTVIDDAYNANPDSMRAGLQALAWIAHGGGDRPAEKRRSWAVLGEMAELGEDAIAEH
DRIGRLAVRLDVSRLVVVGSGRSMSAMHHGAVMEGSWGSADKGAVNVADGEAALALLRAE
LQPGDVVLVKASNAAGLGALADALVSQGSQGGARP
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgatcgaattgaccgtcgccgagatcgccgacatcgtcggcggcaccctggccgacatc
tcgccgcaggacgccgcgcgacgccgcgtcaccgggacggtggaattcgactcgcgcgcc
gtcggacccgggggactgttcctggcgctgccgggcgcgcgctcggacggccacgaccac
gcgggcgcggcgatcgccgccggtgcggtggcggtgctggccgcccggccggtcggcgtt
cccgccgtcgtcgtcgcccccgcggccgcgtcgggatctcgggccggggtgctcgagcac
gacccggacggctcgggcgcggcggtgctcgccgcgctggccaagttggcccaggtggtg
gccgccgaactggtcgccggcgggctcaggatcgtcgggatcaccggatcgtcggggaag
acgtcgaccaaggacctggtggccgccgtgctgaaaccgctcggcgaggtggtcgccccg
cccggctcgttcaacaacgagctggggcatccgtggaccgtgttgcgcgcgacgcccgag
accgacttcctggtcctcgagatgtcggcgcgccacccgggcaacatcgccgcgctggcc
gagatcgccccgccggcgatcggcgtcgtcctcaacgtcggcaccgcgcacctgggcgag
ttcggctcgcgcgaggccatcgctcagacgaaatccgaactgccccaatctgttccggca
tccggggtggtgatcctcaatgccgacgacccggcggtggcggccatggcgggcgtgacc
gcggcccgggtggtgcgggtcagccgcgccgagaacaccagcgcgggccccagccagctg
tgggccgggcccgtctcgctcgacgaggtggccaggccatgcttcacgctgcaccaccgc
gacacctccgggaccacgcaggcgcaggtccggctcggcgtctacggcgaccaccaggtc
accaacgcgctgtgcgccgccgcggtcgcgctggaatgcggcgccgacgtcgaccaggtg
gcggccgcactcgccggcgccggccccgtctcacggcaccggatgcacgtcaccacgcgc
gccgacggcgtcaccgtgatcgacgacgcctacaacgccaaccccgattcgatgcgcgcc
gggctgcaggcgttggcctggatcgcccacggcgggggggaccggccggccgaaaagcgc
aggagttgggcggtgctcggtgagatggccgaactcggcgaggacgcgatcgccgagcat
gatcgcatcggccggctggccgtgcgcttagatgtgtctcgactcgttgtcgtgggaagt
gggaggtcgatgagcgccatgcaccacggagcggtcatggagggttcgtggggctcggcc
gataagggggccgtcaacgtggccgacggcgaggccgccctggcgttgctgcgggccgag
ctgcaacccggcgacgtcgtgctggtcaaggcctccaacgcggccgggctgggggcgctg
gccgacgccctggtatcacaaggctcgcagggcggtgcccgcccgtga
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