Methanocaldococcus infernus: Metin_0455
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Entry
Metin_0455 CDS
T01234
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mif
Methanocaldococcus infernus
Pathway
mif00290
Valine, leucine and isoleucine biosynthesis
mif00620
Pyruvate metabolism
mif01100
Metabolic pathways
mif01110
Biosynthesis of secondary metabolites
mif01210
2-Oxocarboxylic acid metabolism
mif01230
Biosynthesis of amino acids
Module
mif_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mif00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Metin_0455
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Metin_0455
Enzymes [BR:
mif01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Metin_0455
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
ADG13125
UniProt:
D5VRC2
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All DBs
Position
412936..414471
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AA seq
511 aa
AA seq
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MILYKEENEIIKEALKGLKLPDRVYIFDTTLRDGEQTPGVSLTVDEKVEIAINLDKLGVD
IIEAGFPISSSGEYEAVKKIASLNLDAEICALARAVKEDIDRAIDCGVDRIHTFIATSPL
HRKYKLKMSKEEIVEKAVNAIEYIKEHGIKVEFSAEDATRTEIDYLKEVYKKAVEAGADI
INVPDTVGVMIPRATYYLISELRKEIDNISVHCHNDFGLAVANSLAAVEAGAIQCHVTVN
GLGERGGNAALEEVVTSLHFIYGIKTKVKTEELYNISKLVEKLTEVKVQPNKAVVGDNAF
AHESGIHAHGVLAHALTYEPIPPELVGQRRRIILGKHTGTHAIEAKLKELGYTNINKEQF
KEIVKRIKSLGDKGKRVTDKDVEAIVEDVIGRVSKRERVVDLEQIAVMTGNKVIPTASVA
LKINDNLIKTSAIGVGPVDAAVKAIQKAIGEKIKIKEYHIDAITGGTDALAEVVVTLEGY
GKEITTKAAREDIVRASVEAVIDGINKILKK
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgatactatacaaggaggagaatgaaataattaaagaagctctaaaaggactaaagctt
ccagatagggtttatatttttgacaccactctaagggatggagagcaaactccaggggtt
tcactaactgtagatgagaaggttgagatagctatcaacttagataagttaggggttgat
attatagaggctggtttcccaatatcatcaagtggagagtatgaagctgtaaagaagata
gcttctctaaacttagatgctgaaatctgtgcattagcaagggctgttaaggaagatatt
gatagggctatagactgtggagttgatagaatccatacttttatagccacttccccacta
cacagaaagtataagttaaagatgagcaaggaggagattgtagagaaagctgttaatgcc
attgaatatataaaggagcatgggattaaggtagagttctcagctgaagatgctacaagg
actgaaattgattatttaaaggaggtttataagaaagctgttgaagctggagcagatatt
ataaatgttcctgacactgttggggttatgattccaagggctacctattacttaataagt
gagctaaggaaagagattgataatatatctgtccattgtcataatgactttggtttagct
gtagccaacagcttagcagcagttgaagctggagcaattcagtgccatgtaacagttaat
ggcttaggagagagaggaggaaatgctgccttagaagaggttgtcacttccctacacttc
atatatggaataaaaactaaagtgaagacagaagagctttacaatatttcaaagcttgtt
gagaaattaacagaggttaaggttcagcctaataaggctgtggttggagataatgccttt
gcacatgaatctggaattcatgcacatggagttttagcccatgctcttacctatgagcca
atccctccagagttggttgggcaaagaagaagaattattttagggaagcatacagggaca
catgcaatagaggctaagttaaaagaacttggctacaccaacataaataaagagcaattt
aaggagattgtgaagagaataaagagcttaggagataagggtaagagggttacagataaa
gatgttgaagccatagttgaggatgtcattggaagggttagcaagagagaaagagtggtt
gatctggaacagatagctgtgatgacaggaaataaggtgattccaacagcttcagtagct
ctaaaaattaatgataacttgataaaaacctcagccattggtgttggaccagttgatgct
gctgtcaaagctatacagaaggctataggagagaagattaagattaaagagtatcatata
gatgctataactggaggaacagatgccttagctgaggttgttgttaccttagagggatat
ggaaaggagataactactaaagcagcaagagaggatattgtaagagcctcagttgaagct
gtgatagatggaattaacaaaattcttaaaaaataa
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