Methanotorris igneus: Metig_1057
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Entry
Metig_1057 CDS
T01510
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mig
Methanotorris igneus
Pathway
mig00290
Valine, leucine and isoleucine biosynthesis
mig00620
Pyruvate metabolism
mig01100
Metabolic pathways
mig01110
Biosynthesis of secondary metabolites
mig01210
2-Oxocarboxylic acid metabolism
mig01230
Biosynthesis of amino acids
Module
mig_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Metig_1057
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Metig_1057
Enzymes [BR:
mig01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Metig_1057
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Radical_SAM
SpoU_sub_bind
DUF3349
Motif
Other DBs
NCBI-ProteinID:
AEF96596
UniProt:
F6BDN5
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All DBs
Position
1054643..1056199
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AA seq
518 aa
AA seq
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MEPYCKINDIIKEAIKDITPPESIKIFDTTLRDGEQTPGVSLTPDEKVEIAIALNNIGVD
VIEAGFPVSSLGEQEAVKKITSLDLDAEICGLARAVKKDIDVAIDCGVDRIHTFIATSPL
HRKYKLKMDKEEVINKAVEAIEYIKSHGIKVEFSAEDATRTEIDYLIEVYKNAVDAGADV
INVPDTVGVMIPKAMEYLIREIKKEIDVPISVHCHNDFGLAVANSIAAVEAGAEQIHCTV
NGIGERAGNASLEEVVMILKSIYGLNTKIKTEKLTDLSRLVSRLTGIKTQPNKAVVGENA
FAHESGIHAHGVLEHALTYEPIPPELVGQKRKIILGKHTGAHAIKAKLKELGIEVGKNVT
EEQFKEIINRIKSLGDKGKRVTDADVEAIVEDVTKRTLKSERVVDLEQIAVMTGNRVIPT
ASVALRINEEVKKASAIGVGPVDAAVKAIQSVIGEKIKLKEYHINAITGGTDALAEVIVT
LEGYGKEVTTKAAREDIVRASVEAVIEGINKILRSQVK
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atggaaccttactgcaaaataaacgacataatcaaggaggcaataaaagatataacccca
ccagaaagcattaagatatttgatacaactctaagggatggagaacaaacaccaggagtt
tctttaacacctgatgagaaagttgaaattgctatagcgttaaacaatattggtgttgat
gttatagaggcgggatttcccgtatcttcccttggagaacaggaggcagtgaagaaaata
acttcccttgacttagatgcagaaatttgtggacttgcaagagcagtaaagaaagatatt
gacgtagctattgattgtggagttgataggatacacacatttatagcaacatctccattg
cataggaagtataagttaaagatggataaagaagaggttataaacaaggctgttgaggca
atagaatacataaaaagccatggcattaaagttgagttttcagcagaggatgcgacaaga
actgaaattgattatttgatagaggtttataaaaatgcggttgatgctggggcggatgtt
ataaacgtcccagatacagttggagttatgatacctaaggcaatggagtatttaataagg
gagattaaaaaagagatagatgttccaatttcagtgcactgccacaacgattttgggctt
gcagttgctaactccatagcagcagttgaggcaggggcagagcagatacattgcacagtg
aatggtattggagagagagcagggaacgcatcattagaagaggttgttatgattttaaag
agcatatatggactaaatacaaagataaaaactgaaaaattaaccgatttatcaagattg
gtatcaagattaacaggcataaaaactcagccaaacaaggcagtcgttggagaaaatgcc
tttgctcatgagagtggaatacatgcacacggtgttttagagcatgctttaacctatgaa
ccaattccacctgaactcgtagggcaaaaaagaaaaattatccttggaaaacacactgga
gcacatgcaataaaagcaaaacttaaagaactcggtattgaggttgggaaaaacgttaca
gaagagcaatttaaagagatcataaatagaataaaatcacttggagataaaggtaagaga
gtcactgatgccgatgttgaggcaatagtagaggatgttacaaaaagaacattaaaatca
gagagagttgtagatttagagcaaattgcagttatgacagggaatagggtaatcccaaca
gcatcagttgctttaaggataaatgaggaagttaagaaggcatctgctattggtgtaggt
ccagttgatgcagcagttaaggcaatccagtcagttattggggagaagataaagttgaaa
gaataccacataaatgccatcactggaggaactgatgcgttagcagaggtcattgttacg
ttagaaggttatggtaaagaggtaacaacaaaggcagcgagggaagatatcgttagggca
tcagttgaggcagtaattgaggggattaataagatattgaggtctcaagtaaagtaa
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