Mycolicibacterium insubricum: MINS_11300
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Entry
MINS_11300 CDS
T06933
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mij
Mycolicibacterium insubricum
Pathway
mij00860
Porphyrin metabolism
mij01100
Metabolic pathways
mij01110
Biosynthesis of secondary metabolites
mij01120
Microbial metabolism in diverse environments
mij01240
Biosynthesis of cofactors
Module
mij_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mij_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mij00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MINS_11300 (hemD)
Enzymes [BR:
mij01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MINS_11300 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MINS_11300 (hemD)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBZ65701
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Position
1205510..1207141
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AA seq
543 aa
AA seq
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MTTRGRKAKPGRITFVGSGPGDPGLLTMRAKSVLCNAALTFTDPDVPEAVLAIVGSELPP
TVGPAPATDTPDGDAPAVVTGGADVRPALGAPAEVVKTMVAEARAGADVVRLVLGDPLSL
DSVLAEVNAVAKSQVAFEIVPGLPATTAVPTYGGLPLGSSHTVADVRGDVDWAALAAAPG
PLILQAGPEHLADAARTLIDYGLSDSTPCVVTAQGTTCQQRSVETTLAGLTERAALGSSD
PAGPLTGPLVVTIGRTVAHRAKLNWWESRSLYGWTVLVPRTKDQAGEMSERLVGHGALPI
EVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFAEFGLDARAFSGVK
IACVGEATADRVRAFGISPELVPAGEQSSLGLLDEFPPYDDIFDPVNRVLLPRADIATET
LAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTSSSTVRNLVGIAGKP
HARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAEGALPPPRKKS
RRR
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
atgaccacgcgagggcgtaaggccaagccgggccgcatcacgttcgtgggatcggggccg
ggcgatccgggcctgctcacgatgcgggcgaaatcggtgttgtgcaatgccgcgttgacg
ttcaccgaccccgacgtgcccgaggcggtgctggccatcgtcggctccgagctgccgccg
acggtcgggccggcaccggccaccgacacccccgacggcgatgccccggccgtggtgacc
ggcggcgccgacgtccgcccggccctcggcgcgcccgccgaggtcgtcaagaccatggtc
gccgaggcccgcgccggcgccgacgtcgtgcggctggtcctcggtgacccgctgtcgctg
gactcggtgctggccgaggtcaatgccgtcgccaagagccaggtggccttcgagatcgtg
cccgggctgcccgccaccaccgcggtgcccacctacggcggcctcccgctgggctcctca
cacaccgtcgccgacgtccgcggtgacgtcgattgggccgcactggccgccgcgcccgga
ccgctgatcctgcaggccggccccgagcatcttgccgatgccgcccgcaccctcatcgac
tacggcctgtccgactcgacgccctgcgtggtcaccgcgcagggcaccacctgccaacag
cgctcggtggagaccacgctggccgggctgaccgaacgcgccgcgctgggcagctccgac
ccggccggcccgctgaccggcccgctggtggtgaccatcggccgcaccgtggcccatcgc
gccaagctgaactggtgggagagccgctcgctgtacggctggaccgtgctggtgccgcgc
accaaggaccaggccggcgagatgagcgagcggctggtcggccacggcgccctgccgatc
gaggtgccgaccatcgccgtcgaaccgccgcgcagccccgcccagatggaacgcgccgtc
aagggcctggtcgacggccgcttccagtgggtggtgttcacctccaccaacgccgtgcgc
gcggtgtgggagaagttcgccgaattcggcctggacgcccgggcgttctccggggtgaag
atcgcctgcgtcggtgaggccaccgcggaccgggtgcgcgccttcggcatcagccccgag
ctggtgcccgccggtgaacagtcctcgctgggcctgctcgacgagttcccgccgtacgac
gacatcttcgacccggtgaaccgggtgctgctgccgcgcgccgacatcgccaccgagacc
ctcgcggagggcctgcgcgagcgcggctgggagatcgaggacgtcaccgcctaccgcacc
gtgcgcgcggccccgccgccggcgcacacccgcgagatgatcaagaccggcggcttcgac
gcggtctgcttcacctccagctccacggtccgcaacctggtcggcatcgccggcaagccg
cacgcgcggaccatcgtggcgtgcatcgggcccaagaccgccgagacggcagccgaattc
ggactgcgggtcgacgtgcagccggagacggccgccgtcgggccgctggtcgacgcgctc
gccgagcacgccgcccggctgcgcgccgagggcgcactgcccccgccccgcaagaagagc
cggcgccgctag
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