Micromonospora sp. L5: ML5_0563
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Entry
ML5_0563 CDS
T01379
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
mil
Micromonospora sp. L5
Pathway
mil00860
Porphyrin metabolism
mil01100
Metabolic pathways
mil01110
Biosynthesis of secondary metabolites
mil01120
Microbial metabolism in diverse environments
mil01240
Biosynthesis of cofactors
Module
mil_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mil_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mil00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ML5_0563
Enzymes [BR:
mil01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
ML5_0563
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
ADU06113
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Position
583023..584111
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AA seq
362 aa
AA seq
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MRDELAGFTIGVTADRRRDELAALLQRRGARVVLAPALRIVPLADDTDLREATRACLEHP
PDVLMANTGIGMRGWLEAAEGWGLAEPLRTTLARAYVVSRGPKATGAIRAAGLREHWSPD
SESCDEVVEHLVRRGVAGQVVAMQLHGERQPECADALVAAGATVIEVPVYRWAPPADPAP
LHRLIDLVAGRLVDAVTFTSAPAAEALLRAAGDRTETVLEALRGDVLAGCVGTVTAEPLV
RRGVPVSAPSRARLGALVRTIVEELPRRTVSVKAAGHVLTLRGHAAVVDGELRQLAPAPM
AVLRALAASPGKVLSRTALLRTLPRGADEHAVEMAVARLRAGLTAPRVVQTVVKRGYRLR
VD
NT seq
1089 nt
NT seq
+upstream
nt +downstream
nt
atgcgggacgagctggccggcttcaccatcggggtcaccgccgaccggcggcgcgacgaa
ctggccgcgctgctccagcggcgcggtgcgcgggtggtgctcgccccggcgctgcggatc
gtcccgctggccgacgacaccgacctgcgtgaggccacccgggcctgcctggaacacccg
ccggacgtgctgatggccaacaccggcatcggcatgcggggctggctggaggcggccgag
ggctgggggctggccgagccgctgcgcaccacgctcgcccgcgcgtacgtggtgtcccgc
ggtccgaaggcgaccggcgcgatccgtgccgccgggctgcgcgagcactggtccccggat
tcggagagctgcgacgaggtggtcgagcacctggtccggcgcggagtggccggccaggtc
gtggcgatgcaactgcacggcgagcggcagcccgagtgcgccgacgcgctggtggcggcc
ggcgccacggtgatcgaggtgccggtgtaccggtgggcgccgccggccgacccggcgccg
ctgcaccggctcatcgacctggtggccgggcgtctcgtcgacgcggtcacgttcacctcg
gccccggcggccgaggcgctgctgcgcgcggccggggaccgtaccgagacggtgctggag
gcgctgcgcggcgacgtgctggccgggtgcgtcggcaccgtcaccgccgagccgctggtg
cggcgcggggtgccggtgagcgcgccgagccgggcccggctgggcgccctggttcgcacc
atcgtcgaggagctgccccggcgcacggtctcggtgaaggcggccgggcacgtgctgacg
ctgcgcgggcacgccgcggtggtcgacggggagctgcgccagctggcgccggcgccgatg
gcggtgctgcgggcgctcgccgcgtcgccggggaaggtgctctcccgcaccgcgctgctg
cggacgctgccacgtggcgccgacgagcacgcggtggagatggcggtcgcccgcctgcgg
gcggggctgacggcgccccgcgtggtgcagacggtggtcaagcgggggtaccgcctgcgg
gtcgactga
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