Micromonospora sp. L5: ML5_1227
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Entry
ML5_1227 CDS
T01379
Name
(GenBank) D-alanine/D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mil
Micromonospora sp. L5
Pathway
mil00470
D-Amino acid metabolism
mil00550
Peptidoglycan biosynthesis
mil01100
Metabolic pathways
mil01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mil00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
ML5_1227
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ML5_1227
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ML5_1227
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mil01011
]
ML5_1227
Enzymes [BR:
mil01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
ML5_1227
Peptidoglycan biosynthesis and degradation proteins [BR:
mil01011
]
Precursor biosynthesis
Amino acid ligase
ML5_1227
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
Motif
Other DBs
NCBI-ProteinID:
ADU06766
LinkDB
All DBs
Position
1235192..1236325
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AA seq
377 aa
AA seq
DB search
MRETVRIGVVFGGPSAEHEVSCASALGVARALAEQGHRVVALGITRTGGIRLLPEPVLAQ
HLGTVTAGRAIDDRLPVTGPAVELRRGTTTGTVAVGAADAPATVHAELDVVFPVLHGPYG
EDGVVQGLLESLGVPYVGCGILASAVGMDKVAMKRALRAEDVPTTPYVWFDEPTWRAASD
PEKLVVGLRGPLFVKPARMGSSIGISRVADGDNLIAAVEEAFRHDHVVLVEQGVTGRELE
CGVLGGWQPEASAVGEVRVAGGWFDYRQKYFGDADPMIVPAPLPDEVTERIRELSVRAFT
AIGGWGLARVDFLYDETTSDLFVNELNTLPGFTAHSMYPKVWAESGVAYPDVVDRLVALA
FTRHAARPSREHPGGTP
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgagagagacagtgcggatcggtgtcgtgttcggaggcccgtcggcggaacacgaggtc
tcctgcgcctcggcgctcggcgtggcccgggccctggccgagcaggggcaccgggtggtg
gcgctcggcatcacccgcaccggcgggatccggctgctgcccgaaccggtgctcgcgcag
cacctcggcaccgtgacggccgggcgggcgatcgacgaccggctgccggtcaccggtccg
gcggtcgagctgcgacgcggaacgacaaccggcaccgtcgcggtcggcgcggccgacgcc
cccgcgactgtgcacgccgaactggacgtggtgttcccggtgctgcacggcccgtacggc
gaggacggcgtggtgcaggggctgctggagtcactgggcgtgccgtacgtcgggtgcggc
atcctcgcctccgcagtcggcatggacaaggtggcgatgaagcgggcgctgcgggccgag
gacgtgccgaccacgccgtacgtctggttcgacgaaccgacctggcgggccgcgtccgac
ccggagaagctggtggtcgggctgcgcgggccgctgttcgtcaagccggcccggatgggc
tcctcgatcgggatctcccgggtggccgacggcgacaacctgattgccgccgtggaggag
gcgttccggcacgaccacgtggtgctcgtcgagcagggcgtgaccggccgggaactggag
tgcggcgtgctcggcggctggcagccggaggcgtcggcggtcggcgaggtccgggtcgcg
ggcggctggttcgactaccggcagaagtacttcggcgacgccgacccgatgatcgtcccg
gcgccgctgccggacgaggtcaccgagcggatccgcgagctgtcggtgcgggcgttcacc
gcgatcggcggctggggcctggcccgtgtcgacttcctctacgacgagaccaccagcgac
ctgttcgtcaacgagctgaacacgctgccgggcttcaccgcccactcgatgtacccgaag
gtgtgggccgagtccggcgtcgcgtaccccgatgtggtggaccggctcgtcgcgcttgcc
ttcaccaggcacgcggcccggccgtcgcgcgaacaccccgggggtacgccgtga
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