Mycobacterium sp. JLS: Mjls_3271
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Entry
Mjls_3271 CDS
T00482
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mjl
Mycobacterium sp. JLS
Pathway
mjl00300
Lysine biosynthesis
mjl00550
Peptidoglycan biosynthesis
mjl01100
Metabolic pathways
mjl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mjl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mjls_3271
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mjls_3271
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mjls_3271
Enzymes [BR:
mjl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mjls_3271
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABN99049
UniProt:
A0A5Q5CI83
LinkDB
All DBs
Position
complement(3429715..3431208)
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AA seq
497 aa
AA seq
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MIELTLARVAEIVGGRLADITPEDAAATRITGTVEFDSRAVTAGGLFLALPGARSDGHDF
AAAAVAAGAAAVLAARPVGVPAVVVPPAAGPEGSGVLEHDTDGAGAAVLAALARLAAAVA
AELVDGGLRIVGITGSSGKTSTKDLVAAVLAPLGEVIAPPGSFNNELGHPWTVLRADRST
DFLVLEMSARHPGNIAALAAIAPPSIAVVLNVGTAHLGEFGSREAIAATKSELPQAVPES
GVVILNADDSAVAAMAEVTAARVVRVSREPGADIWADAVTLDELARPRFTLHAAGGEVPV
NLAVHGDHQVSNALCAAAVALECGATLDQVAAALAGAGPVSRHRMQVTTREDGVTVVNDA
YNANPDSMRAGLKALAWMSRGGAAKRRSWAVLGEMAELGDDSISEHDSIGRLAVRLDVSR
LVVVGTGRSASAMHQGAVMEGSWGAEATRVDDADAALALLSDELQPGDVVLVKASNSAGL
GALADSLTAGRDGTATR
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgaactgaccctggcccgggtggccgagatcgtcggcggccggctggccgacatc
acccccgaggacgccgccgccacccggatcaccggaaccgtcgaattcgactcgcgcgcc
gtcacggccggcgggctgttcctggcgctgccgggtgcccgctccgacggccacgacttc
gccgcggccgccgtcgccgcgggggccgcggcggtgctggccgcccgtccggtcggcgtg
cccgccgtcgtcgtccctcccgccgcggggcccgagggctccggtgtgctcgaacacgac
accgacggcgccggtgccgcggtgctggcggcgctggcccggttggccgccgcggtcgcc
gccgaactggtcgacggcgggctgcggatcgtcgggatcaccggatcgtcggggaagacc
tcgacgaaggatctggtggccgccgtactcgccccgctgggggaggtgatcgccccgccg
ggttcgttcaacaacgaactcggtcacccgtggacggtgctgcgcgccgaccgctcgacc
gacttcctggtgctggagatgtcggcgcggcatccgggcaacatcgccgcgctggccgcg
atcgccccgccgtcgatcgcggtggtgctcaacgtgggcaccgcccacctcggcgagttc
ggttcgcgcgaggccattgccgccacgaaatccgaactgccgcaggctgttccggaatcc
ggtgtggtgatcctcaatgccgacgacagtgcggtcgccgcgatggcggaggtgacggcg
gcccgggtggtgcgggtgtcgcgggaacccggcgccgacatctgggcggacgcggtgacg
ctcgacgaactcgctcgcccgcgtttcaccctgcacgccgcgggcggtgaggtgccggtg
aacctcgcggtgcacggcgaccaccaggtgtccaacgcactgtgtgcggccgcggtcgcg
ctggaatgcggggccaccctggaccaggtcgcggccgcgctcgccggggccggtccggtg
tcgcggcaccgcatgcaggtcaccacgcgcgaggacggcgtcaccgtggtcaacgacgcc
tacaacgcgaacccggactccatgcgggcggggctcaaggcgctggcatggatgagtagg
ggcggcgcggccaaacgccggagctgggccgtgctcggcgagatggccgaactcggtgac
gactcgatatccgagcacgacagcatcggccgactggcggtgcgcttagatgtgtcacga
ctcgtcgtcgtaggaaccgggaggtcggcaagcgccatgcatcagggggcggtcatggag
ggatcctggggggcggaggccacccgggtcgatgacgccgacgctgcgctggcgctgttg
agcgacgaactgcagcccggtgatgtcgtgctggtgaaggcgtcgaactcggcgggcctc
ggtgcgctggccgattcgctgaccgccggacgtgacgggaccgccacccgatga
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