KEGG   Manis javanica (Malayan pangolin): 108383520
Entry
108383520         CDS       T06054                                 
Symbol
ADCY6
Name
(RefSeq) adenylate cyclase type 6 isoform X1
  KO
K08046  adenylate cyclase 6 [EC:4.6.1.1]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv00230  Purine metabolism
mjv01100  Metabolic pathways
mjv01522  Endocrine resistance
mjv04015  Rap1 signaling pathway
mjv04022  cGMP-PKG signaling pathway
mjv04024  cAMP signaling pathway
mjv04062  Chemokine signaling pathway
mjv04072  Phospholipase D signaling pathway
mjv04081  Hormone signaling
mjv04082  Neuroactive ligand signaling
mjv04114  Oocyte meiosis
mjv04211  Longevity regulating pathway
mjv04213  Longevity regulating pathway - multiple species
mjv04261  Adrenergic signaling in cardiomyocytes
mjv04270  Vascular smooth muscle contraction
mjv04371  Apelin signaling pathway
mjv04540  Gap junction
mjv04611  Platelet activation
mjv04713  Circadian entrainment
mjv04714  Thermogenesis
mjv04723  Retrograde endocannabinoid signaling
mjv04724  Glutamatergic synapse
mjv04725  Cholinergic synapse
mjv04727  GABAergic synapse
mjv04742  Taste transduction
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04911  Insulin secretion
mjv04912  GnRH signaling pathway
mjv04913  Ovarian steroidogenesis
mjv04914  Progesterone-mediated oocyte maturation
mjv04915  Estrogen signaling pathway
mjv04916  Melanogenesis
mjv04918  Thyroid hormone synthesis
mjv04921  Oxytocin signaling pathway
mjv04923  Regulation of lipolysis in adipocytes
mjv04924  Renin secretion
mjv04925  Aldosterone synthesis and secretion
mjv04926  Relaxin signaling pathway
mjv04927  Cortisol synthesis and secretion
mjv04928  Parathyroid hormone synthesis, secretion and action
mjv04934  Cushing syndrome
mjv04935  Growth hormone synthesis, secretion and action
mjv04961  Endocrine and other factor-regulated calcium reabsorption
mjv04962  Vasopressin-regulated water reabsorption
mjv04970  Salivary secretion
mjv04971  Gastric acid secretion
mjv04972  Pancreatic secretion
mjv04976  Bile secretion
mjv05032  Morphine addiction
mjv05163  Human cytomegalovirus infection
mjv05166  Human T-cell leukemia virus 1 infection
mjv05200  Pathways in cancer
mjv05207  Chemical carcinogenesis - receptor activation
mjv05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    108383520 (ADCY6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    108383520 (ADCY6)
   04371 Apelin signaling pathway
    108383520 (ADCY6)
   04072 Phospholipase D signaling pathway
    108383520 (ADCY6)
   04024 cAMP signaling pathway
    108383520 (ADCY6)
   04022 cGMP-PKG signaling pathway
    108383520 (ADCY6)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    108383520 (ADCY6)
   04081 Hormone signaling
    108383520 (ADCY6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    108383520 (ADCY6)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    108383520 (ADCY6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108383520 (ADCY6)
   04062 Chemokine signaling pathway
    108383520 (ADCY6)
  09152 Endocrine system
   04911 Insulin secretion
    108383520 (ADCY6)
   04923 Regulation of lipolysis in adipocytes
    108383520 (ADCY6)
   04912 GnRH signaling pathway
    108383520 (ADCY6)
   04913 Ovarian steroidogenesis
    108383520 (ADCY6)
   04915 Estrogen signaling pathway
    108383520 (ADCY6)
   04914 Progesterone-mediated oocyte maturation
    108383520 (ADCY6)
   04921 Oxytocin signaling pathway
    108383520 (ADCY6)
   04926 Relaxin signaling pathway
    108383520 (ADCY6)
   04935 Growth hormone synthesis, secretion and action
    108383520 (ADCY6)
   04918 Thyroid hormone synthesis
    108383520 (ADCY6)
   04928 Parathyroid hormone synthesis, secretion and action
    108383520 (ADCY6)
   04916 Melanogenesis
    108383520 (ADCY6)
   04924 Renin secretion
    108383520 (ADCY6)
   04925 Aldosterone synthesis and secretion
    108383520 (ADCY6)
   04927 Cortisol synthesis and secretion
    108383520 (ADCY6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108383520 (ADCY6)
   04270 Vascular smooth muscle contraction
    108383520 (ADCY6)
  09154 Digestive system
   04970 Salivary secretion
    108383520 (ADCY6)
   04971 Gastric acid secretion
    108383520 (ADCY6)
   04972 Pancreatic secretion
    108383520 (ADCY6)
   04976 Bile secretion
    108383520 (ADCY6)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    108383520 (ADCY6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    108383520 (ADCY6)
  09156 Nervous system
   04724 Glutamatergic synapse
    108383520 (ADCY6)
   04727 GABAergic synapse
    108383520 (ADCY6)
   04725 Cholinergic synapse
    108383520 (ADCY6)
   04723 Retrograde endocannabinoid signaling
    108383520 (ADCY6)
  09157 Sensory system
   04742 Taste transduction
    108383520 (ADCY6)
   04750 Inflammatory mediator regulation of TRP channels
    108383520 (ADCY6)
  09149 Aging
   04211 Longevity regulating pathway
    108383520 (ADCY6)
   04213 Longevity regulating pathway - multiple species
    108383520 (ADCY6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    108383520 (ADCY6)
   04714 Thermogenesis
    108383520 (ADCY6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108383520 (ADCY6)
   05207 Chemical carcinogenesis - receptor activation
    108383520 (ADCY6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108383520 (ADCY6)
   05163 Human cytomegalovirus infection
    108383520 (ADCY6)
  09165 Substance dependence
   05032 Morphine addiction
    108383520 (ADCY6)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    108383520 (ADCY6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108383520 (ADCY6)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108383520 (ADCY6)
Enzymes [BR:mjv01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     108383520 (ADCY6)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC DUF5134
Other DBs
NCBI-GeneID: 108383520
NCBI-ProteinID: XP_017495566
LinkDB
Position
Unknown
AA seq 1235 aa
MGGPRTAWGEPAAVGAGGQGDGEARTPSSPPSPGAACLPASPSARASSWLLRSGESMSWF
GGLLVPKVDERKTAWGERNGQKRLRHGPRTSGFCTPRYMSCLRDAQPPSPTPAAPPQCLW
QNEAFTRRGGLGKSTELGLRAVALGFEDTEATVAVGAAEVAPDVAPRSRRSCWRRLARVF
QSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLLLLMAVLLAFHAAPAVPQPAYVALLAC
AAALFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCPVFFV
YITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRWDAFLWKQLGANMLLFLCTNVIGICT
HYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMM
FHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKIL
GDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLG
LRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQH
TETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDD
SSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKGRAYCP
AQPPLPQYSRKVDPRFGAYVACALLVFCFICFIQLLVFPRSTLLLGIYASIFLLLLITVL
TCAIYSCGSLFPVALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPLRTCA
ARMLNLTPAIITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFIGNMLLSLLASSVFLHI
SSIGKLAMVFALGLVYLALLLLGPPATIFDNYDLLLGVHGLASSNGTFDGLDCPAAGRVA
LKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILP
KDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIA
DFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQAGRSHITALADYAMRLMEQMKHI
NEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLY
QVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3708 nt   +upstreamnt  +downstreamnt
atgggtgggccccgtacggcctggggggagcctgcggccgtgggggctggaggtcaggga
gatggggaagcaaggactccgagctccccgccctcacccggtgccgcatgcctccctgcc
tcaccctccgcccgggcgagttcctggctccttcgatcaggcgaaagcatgtcatggttt
ggtggcctcctggtccccaaagtggatgaacggaaaacagcctggggtgaacgcaatggg
cagaagcgtctgcgccatggccctcggaccagtggcttctgcacaccccgctacatgagc
tgcctccgggatgcacagccacctagccccacccctgcagctccccctcagtgcctgtgg
cagaacgaggccttcacgcggaggggtggcctgggcaagagcacggagctggggctgcgg
gcagtggctctgggctttgaggacactgaggcaacggtggctgtcggggcagctgaggtg
gcacctgatgtggcacccaggagcaggcgatcctgttggcgccgtctggcgcgggtattc
caatccaagcagttccgctcagccaagctggagcgcctgtaccagcggtacttcttccaa
atgaaccagagcagcctgacgctgctgatggcggtgctcctgctgctaatggcagtgctt
ctggcctttcatgctgcgcctgcggtccctcagccggcctatgtggccctgctggcttgt
gctgcggccctcttcgtggcactcatggtggtttgtaaccgacacagcttccgccaggac
tccatgtgggtggtgagctacgtggtcctgggcatccttgcggctgtgcaggtcgggggt
gccctggcagccaacccccacagcccctctgttggcctctggtgccctgtgttctttgtc
tacatcacctacacgctcctacccatccgcatgcgggcagctgtcttcagtggactgggc
ctctccaccttgcacctgatcttggcctggcaactcaaccggtgggatgccttcctctgg
aagcagctcggtgccaacatgctgctgttcctctgcaccaacgtcatcggtatctgcaca
cactacccagctgaggtgtctcagcgccaggcctttcaggagacccgtggttacatccag
gcccggctgcacctgcagcacgagaatcggcagcaggagcggctgctgctgtcggtattg
ccccagcatgttgccatggagatgaaagaagacatcaacacaaagaaagaagacatgatg
ttccacaaaatctacatccagaagcacgacaatgtcagcatcctgtttgcggacattgaa
ggcttcaccagcctggcatcgcagtgcactgctcaggagctggtcatgaccctgaacgag
ctctttgcccggtttgacaagctggctgcggaaaatcactgcctgaggatcaagatctta
ggggactgctactactgtgtgtcagggctgccagaggcccgggcagaccatgcccactgc
tgtgtggagatgggggtggacatgattgaggccatctcgctggttcgtgaagtgacgggt
gtgaatgtgaacatgcgtgtgggcatccacagtgggcgtgtgcactgcggcgtccttggt
ctgcggaaatggcagtttgatgtgtggtccaatgatgtgactctggccaaccatatggag
gcggggggccgggccggccgcatccacatcactcgggccacactgcagtacctgaacggg
gactacgaggtggagccaggtcgcggcggcgagcgcaatgcatacctcaaggagcagcac
actgagaccttcctcatcctgggagccagccagaaacggaaagaggagaaggccatgctg
gctaagctgcagcggacacgggccaactccatggagggactgatgccacgctgggtaccc
gaccgcgccttctcccggaccaaggactctaaggctttccgccagatgggcattgatgat
tccagcaaagacaaccggggcgcccaagatgccctgaaccctgaggatgaggtagatgag
ttcctgggccgtgccattgatgctcgtagtattgaccaactgcgcaaggaccatgtgcgc
cggtttttgctcaccttccagagagaggatcttgaaaagaagggcagagcctactgccca
gcccagcctcctctccctcagtactcgaggaaggtggacccccgcttcggagcctatgtg
gcctgtgccctgctggtcttctgcttcatctgtttcatccagctcctagtcttcccacgc
tcaaccctcctgcttgggatctatgccagcatctttctgctgttgctgatcacagtgctg
acctgtgccatatactcctgtggctctctcttccccgtggccctgcaacgcctgtcccgc
agcatcgtccgctcccgggcacacagcactgccgttggcatcttttcggtcctgcttgtg
ttcacctctgccattgccaacatgttcacctgtaaccacacccccttacggacctgcgca
gcccggatgctgaatttaacgccggccatcatcactgcctgccacctacagcagctcaat
tactctctgggcctggatgctcccctgtgtgagggcaccgcacccacctgcagcttcccc
gagtacttcatcgggaacatgctgttgagtctcttggccagctctgtcttcctgcatatc
agcagcattgggaagctggccatggtctttgctctggggctcgtctacttggcactgctg
ctgttgggtcccccagctaccatctttgacaactatgacctgctgcttggtgtccatggc
ttggcttcatccaatgggacctttgacgggctggactgcccagctgcagggagggtggca
ctcaaatatatgacccctgtgatactgctggtgtttgcgctggcgctgtatctgcatgcc
cagcaggtggaatccactgctcgcctggacttcctctggaaactgcaggcaacaggggag
aaggaggagatggaggagctccaggcatacaaccggaggctgctgcataacattctgccc
aaggacgtggctgcccacttcctggcccgggagcgccggaatgatgagctctactatcag
tcctgtgagtgtgtggccgtcatgtttgcttccattgccaacttctctgagttctacgtg
gagctggaggcaaacaatgagggtgtcgagtgcctgcggctgctcaatgaaatcatcgca
gactttgatgagatcatcagcgaggagcggttccggcagctggagaagatcaagacaatt
ggtagcacttacatggccgcctctgggctgaacgccagcacctatgatcaggcaggccgc
tcccacatcactgcgcttgcggactacgccatgcggctcatggagcagatgaagcacatc
aatgagcactccttcaacaacttccagatgaagatcgggctgaacatgggcccagtcgtg
gcaggcgtcattggggctcggaagccgcagtatgacatctgggggaacacagtgaatgtc
tctagccgtatggatagcacgggggtccctgaccgaatccaggtgaccacggacctgtac
caggttctagcggccaagggctaccagctggaatgtcgaggggtggtcaaggtgaagggc
aagggggagatgaccacctacttcctcaatgggggccccagcagttag

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