Manis javanica (Malayan pangolin): 108385494
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Entry
108385494 CDS
T06054
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04148
Efferocytosis
mjv04260
Cardiac muscle contraction
mjv04261
Adrenergic signaling in cardiomyocytes
mjv04380
Osteoclast differentiation
mjv04919
Thyroid hormone signaling pathway
mjv04972
Pancreatic secretion
mjv05010
Alzheimer disease
mjv05017
Spinocerebellar ataxia
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05410
Hypertrophic cardiomyopathy
mjv05412
Arrhythmogenic right ventricular cardiomyopathy
mjv05414
Dilated cardiomyopathy
mjv05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
108385494 (ATP2A1)
04024 cAMP signaling pathway
108385494 (ATP2A1)
04022 cGMP-PKG signaling pathway
108385494 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
108385494 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108385494 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
108385494 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
108385494 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
108385494 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
108385494 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
108385494 (ATP2A1)
05017 Spinocerebellar ataxia
108385494 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
108385494 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
108385494 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
108385494 (ATP2A1)
05414 Dilated cardiomyopathy
108385494 (ATP2A1)
05415 Diabetic cardiomyopathy
108385494 (ATP2A1)
Enzymes [BR:
mjv01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
108385494 (ATP2A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
108385494
NCBI-ProteinID:
XP_017498429
LinkDB
All DBs
Position
Unknown
AA seq
1000 aa
AA seq
DB search
MEASHSKTTEECLAYFGVSETTGLTPDQVKRNLEKYGPNELPAEEGKSLWELVLEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPIPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGHTCDLNQFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNEAKGIYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTSRVPMTGPV
KDKIMSVIKEWGTGRDTLRCLALATRDTPPRREEMTLDDATRFMEYETDLTFIGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEDEEVRDRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRTPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYAEDGPRVTYSQLTHFMQCNEENPDFEGLDCEVFEAPEPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLMGSICLSMSLHFLILYVDPLPMIFKLRA
LDCNQWFMVLKISLPVIGLDEILKFVARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggcttcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggcctgaccccggaccaagttaagcggaatctggagaaatatggccccaatgag
ctccctgctgaggaagggaagtccctgtgggagctggtgttagagcagtttgaggacctc
ctggtgcggatcctcctcctggctgcctgcatttcctttgtgctggcctggtttgaggaa
ggtgaagagaccattaccgcctttgttgagccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggtgtttggcaggagcgaaatgcagagaatgctatcgaggctctgaag
gaatatgaacctgagatggggaaagtctaccgggctgaccgcaaatcagtgcaaagaatc
aaggctagggacattgtccctggagacattgtggaagtggctgtgggagacaaagtccct
gcagacatccgcatcctttccattaaatccaccaccctccgggtggaccagtccattctg
acaggtgagtctgtatctgtcatcaagcacacagaccctattcctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggcaccaacattgcagccggcaaggcttta
ggcatcgtggccaccactggtgtgagcaccgagattgggaagatccgtgaccaaatggcc
gccacagaacaggacaagacccctttgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgtgtggctgtctggcttatcaacattggccatttcaat
gatcccgtccatgggggctcttggatacggggtgccatctactactttaagattgctgtg
gccctggctgtggctgcaatcccggaaggccttcctgcagtcatcaccacctgcctggcc
ttgggcacccgccggatggcaaagaaaaatgcaattgtgaggagcctgccttctgtggag
actttgggctgcacctctgtcatctgttccgacaagacaggcaccctcaccaccaaccag
atgtcggtctgcaagatgttcatcattgacaaggtggatgggcacacctgcgacctgaat
cagttctctatcacaggctccacttatgctccagaaggagaggtcttgaagaacgataag
ccagtccgggcagggcagtatgatgggctggtggagctggccaccatctgtgccctctgc
aatgactcctccttggacttcaatgaggccaaaggtatttatgagaaggtgggtgaggcc
accgagacagcactcaccaccctggtggagaagatgaatgtattcaacactgatgtgaga
agcctgtcaaaggtggagagggccaatgcctgcaactcagtgatccgccagctaatgaag
aaggaattcaccctggagttctcccgagacagaaagtccatgtctgtctattgctcccca
gccaaatcccgggctgctgtgggcaacaagatgttcgtcaagggtgcccctgagggggtt
attgaccgctgtaactatgtgagagttggcacctcccgcgtgccgatgacagggccagtg
aaggacaagatcatgtcggtgatcaaggaatggggcactggccgggacaccctacgctgc
ctggccctggccacccgggacacccctccgagacgagaggagatgaccctggatgacgct
accaggttcatggagtacgagacggacctgacattcattggtgtggtgggcatgttggac
ccgccccgcaaggaggtcacgggctctatccagctgtgccgcgatgctggcattcgggtg
atcatgatcactggggacaacaagggcacagccattgccatctgccgacgaattggcatc
tttggggaggatgaggaggtgagagaccgagcctacactggccgggagttcgacgacctg
cccctggctgagcagcgggaagcttgccgtcgtgcttgctgctttgcccgtgtggagccc
tcccataagtccaagatcgtggagtatctgcagtcctttgatgagatcacagccatgaca
ggagatggcgtcaatgacgcccctgccctgaagaaggctgagatcggcattgccatgggg
tcgggcactgccgtggctaagaccgcctctgagatggtgctggctgatgataacttctcc
accatcgtggccgctgtggaggagggccgcgccatctacaacaacatgaagcagttcatc
cgctacctcatttcctccaacgtgggcgaggtggtctgcatcttcctgacagccgccttg
gggctgcctgaagccctgatccctgtgcaactgctgtgggtgaacttggtgactgatggg
ctcccagccacagccctgggcttcaacccaccagatctggacatcatggaccggcccccc
cggactcccaaggagcccctcatcagtggatggctcttcttccgctacatggcaattggg
ggttatgtgggtgcagccactgtgggagcagctgcctggtggttcctgtatgcggaggat
gggcctcgggtcacctacagccagctgactcacttcatgcagtgcaatgaagagaatcct
gactttgagggtctggactgtgaggtctttgaggccccagagcccatgaccatggccttg
tctgtgctggttaccatcgagatgtgcaatgcgctcaacagcctgtctgagaaccagtcc
ctcctgcggatgccaccatgggtgaatatctggctgatgggctccatctgcctgtccatg
tccctccatttcctcatcctctacgttgaccctctgccgatgatcttcaagctccgggcc
ctagactgcaaccagtggtttatggtcctcaagatctcattgccagtcattgggcttgat
gaaatcctcaagtttgttgctcgaaactacctggaggatccagaagatgaaagaaggaag
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