Manis javanica (Malayan pangolin): 108385741
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Entry
108385741 CDS
T06054
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01521
EGFR tyrosine kinase inhibitor resistance
mjv04010
MAPK signaling pathway
mjv04014
Ras signaling pathway
mjv04015
Rap1 signaling pathway
mjv04020
Calcium signaling pathway
mjv04072
Phospholipase D signaling pathway
mjv04144
Endocytosis
mjv04151
PI3K-Akt signaling pathway
mjv04510
Focal adhesion
mjv04518
Integrin signaling
mjv04540
Gap junction
mjv04630
JAK-STAT signaling pathway
mjv04810
Regulation of actin cytoskeleton
mjv05163
Human cytomegalovirus infection
mjv05200
Pathways in cancer
mjv05206
MicroRNAs in cancer
mjv05214
Glioma
mjv05215
Prostate cancer
mjv05218
Melanoma
mjv05230
Central carbon metabolism in cancer
mjv05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108385741 (PDGFRA)
04014 Ras signaling pathway
108385741 (PDGFRA)
04015 Rap1 signaling pathway
108385741 (PDGFRA)
04630 JAK-STAT signaling pathway
108385741 (PDGFRA)
04020 Calcium signaling pathway
108385741 (PDGFRA)
04072 Phospholipase D signaling pathway
108385741 (PDGFRA)
04151 PI3K-Akt signaling pathway
108385741 (PDGFRA)
09133 Signaling molecules and interaction
04518 Integrin signaling
108385741 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
108385741 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
108385741 (PDGFRA)
04540 Gap junction
108385741 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108385741 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108385741 (PDGFRA)
05206 MicroRNAs in cancer
108385741 (PDGFRA)
05230 Central carbon metabolism in cancer
108385741 (PDGFRA)
05231 Choline metabolism in cancer
108385741 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
108385741 (PDGFRA)
05218 Melanoma
108385741 (PDGFRA)
05215 Prostate cancer
108385741 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
108385741 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108385741 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108385741 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mjv04090
]
108385741 (PDGFRA)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
108385741 (PDGFRA)
Protein kinases [BR:
mjv01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
108385741 (PDGFRA)
CD molecules [BR:
mjv04090
]
Proteins
108385741 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
Kinase-like
Motif
Other DBs
NCBI-GeneID:
108385741
NCBI-ProteinID:
XP_073093700
LinkDB
All DBs
Position
5:complement(131665773..131708510)
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHRALLVSGCLLTGLSLILCQLSLPSILPNENEKVVRLNSSFSLSCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVTVLAVVNASAAHTGLYTCYYNHTQTEENEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLLSSDGVVTASYDSRQGFNG
TFGVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGDTIVVTCAVFNN
EVVDLQWTYPGEVKGKGRTTLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSQLEAVDLHEVKHFVVDVEAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWMILANNISNIITEVHPRD
RSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEIKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKEWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatcgggccctcctggtctcaggctgtctgctcacagggctgagccta
atcctctgccagctttcattgccctctatccttccaaatgaaaatgaaaaggttgtgcgg
ctgaattcatccttttctctgagctgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaatgaggagaacaacagtggcctt
tttgtgacagtgctggcagtggtcaatgcctccgcagcccacacgggattgtacacttgc
tattacaaccacactcagacagaggaaaatgagattgaaggcagacgaatctacatctat
gtaccagacccagatgtagcctttgtacctctaggaatgacagattatttagtcattgtg
gaggatgatgattctgccatcataccttgtcgcacaactgatcctgagaccccggtgacc
ttactcagcagtgacggggtagtgacggcctcctatgacagcagacagggctttaacgga
accttcggtgttgggccctatatctgtgaggctactgtcagagggaagaagttccagacc
atcccatttaatgtgtatgctttaaaagcaacatcagaacttgatctagaaatggaagct
cttaaaactgtatataagtcgggggacacgattgtggtcacctgcgccgtctttaacaac
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggtaaaggccggacaacg
ctcgaggaaatcaaggtcccatccatcaaactggtgtacactctgacagtccctgaggcc
acagtgaaagacagcggagattacgaatgtgctgcacgccaggccaccaaggaggtcaaa
gaaatgaagaaagtcaccatctctgtccatgagaaagggttcattgaaatcaaacccaac
tttagccagttggaagctgtggacctgcatgaagtcaaacattttgtggtggacgtggag
gcctatccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
actgagatcaccactgacatagaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagacagtggccattatactattgtagttcaaaacgaagat
gacgtgaagagctatactttcgaactgttaactcaggttccctcatctattctggactta
gtggatgaccaccatggttctaccgggggacagaccgtgagatgcacagctgaagggaca
cctcttcctgatattgagtggatgatttgcaaggatatcaagaaatgtaataatgaaacc
tcgtggatgattttggccaacaacatctcaaacatcatcacagaggtccacccgcgagac
aggagtacggtggagggcagagtgactttcgccaaagtggaggagaccattgcggttcga
tgtctggcaaagaatctccttggggctgagaatcgagagctgaagctggtggctcccact
ctgcgttctgaactcacggtggcggccgcagtcctggtgctgttggtgattgtcatcatc
tcacttattgttctggttgtcatttggaagcagaaaccgaggtatgaaattcgttggagg
gtcattgaatcaatcagccctgatggacacgaatatatttatgtggatccgatgcagctg
ccttatgactcaagatgggagtttccgagagatggactagtgcttggtcgtatcctggga
tctggtgcatttgggaaagtggttgaaggaactgcctatggattaagccggtcccagcct
gtcatgaaagtagcagtgaagatgctaaaacccacagccagatctagtgaaaaacaagct
ctcatgtctgaactgaagataatgactcacctggggccgcatttaaatattgtaaacttg
ctgggagcctgtaccaagtcaggccccatttacatcatcaccgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgccacccagagaag
ccaaagaaagagctggacatctttggattgaaccctgctgatgagagcacacggagttac
gttattttatcttttgaaaacaatggtgactatatggacatgaagcaagctgataccaca
cagtatgtcccaatgctggaaaggaaagaggtttctaaatattcggacatccagagatca
ctgtatgatcgcccagcctcgtataagaagaaatccatgttagactcagagatcaaaaac
ctcctttcggatgataactcagaaggccttactttgttggatttgttaagctttacttac
caagttgcccgaggcatggagttcttggcttcaaaaaattgtgtccaccgggacctggct
gctcgcaatgtcctcctggcacaagggaaaattgtgaagatctgtgactttggcctggcc
agagacatcatgcacgactcgaactacgtgtcaaaaggcagtacttttctcccagtgaag
tggatggctccggagagcatctttgacaacctgtacactacactgagtgacgtctggtct
tacggcattctcctctgggagatcttttccctcggtggcaccccctaccccggcatgatg
gtggattctaccttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gctaccagtgaagtctatgagatcatggtgaagtgctggaacagtgagccagagaagaga
ccctccttttaccacctgagtgagattgtggagaatcttctgcctggacaatacaaaaag
agctatgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcacgcatg
cgcgtggactcggacaacgcctacattggcgtcacctacaagaacgaggaagacaagctg
aaggagtgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cctctgcccgacatagaccctgtaccggaggaagaagacctgggcaagaggaacagacac
agctcgcagacctctgaagagagtgccatcgagacaggttccagcagttctacattcatc
aagagagaggatgagaccattgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtagaggacagcttcctgtaa
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