Manis javanica (Malayan pangolin): 108385826
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Entry
108385826 CDS
T06054
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00260
Glycine, serine and threonine metabolism
mjv00630
Glyoxylate and dicarboxylate metabolism
mjv00670
One carbon pool by folate
mjv01100
Metabolic pathways
mjv01200
Carbon metabolism
mjv01230
Biosynthesis of amino acids
mjv01240
Biosynthesis of cofactors
mjv01523
Antifolate resistance
mjv04981
Folate transport and metabolism
Module
mjv_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
108385826 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
108385826 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
108385826 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
108385826 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
108385826 (SHMT2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
108385826 (SHMT2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
DUF7548
Motif
Other DBs
NCBI-GeneID:
108385826
NCBI-ProteinID:
XP_017498901
LinkDB
All DBs
Position
Unknown
AA seq
533 aa
AA seq
DB search
MRCQISRFQSPSLTRPELVAGDLLRLGVAMLHFSLLWATRPLQRCGQLVRMAIRCQHSEA
AQTQTGETTRGWTGQERLSDSDPELWELLQKEKDRQCRGLELIASENFCSRAALEALGSC
LNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAY
TALLQPHERIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPQTGLIDYEQLAL
TARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFQHA
DVVTTTTHKTLRGARSGLIFYRKGVRTVDPKTGQEIPYTFEDRINFAVFPSLQGGPHNHA
IAAVAVALKQACSPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGL
DGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREVDFRRVVDFIDEG
VNIGLEVKSKTAKLQDFKSFLLKDPEIRHRLADLRQRVEQFARAFPMPGFHER
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgcgctgtcagatcagtcgttttcagtccccttccttaacccggccagagttggtggct
ggagacctcctgagacttggggtggcgatgctgcacttctctttgctctgggcgactcgg
cctctgcagagatgtggtcagctggtcaggatggccatacggtgccagcacagtgaggca
gcccagacccagactggagaaacaaccaggggctggacaggccaggagaggctgtcagac
agtgatcctgagctgtgggagctgctgcagaaagagaaggacaggcagtgtcgtggcctg
gagctcattgcttccgagaatttctgcagccgagctgcgctggaagctctggggtcctgt
ctgaacaacaaatactcggagggttatcctggcaagagatattacgggggagcagaggta
gtggatgaaattgagctgctgtgtcagcgccgggccctggaggcctttgatctggatcct
gcacagtggggagtcaatgtccagccctactcagggtccccagccaatctggccgcctac
acagccctcctgcagcctcacgaacgaatcatggggctggacctgccagatgggggccat
cttacccatgggtatatgtctgatgtcaagcggatctcagcgacatccatcttcttcgag
tctatgccttataagctgaatccccaaactggcctcatcgactatgagcagctggcactc
actgctcggcttttccggcctcggctcattatagctggcaccagtgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaggcacacctgctggcagac
atggcccacatcagtggcctggtggctgccaaggtgatcccctcacctttccagcatgca
gatgttgttaccaccaccactcacaagacccttcgaggggccaggtcaggactcatcttc
taccggaagggggttcggactgtggaccccaagactggccaggagatcccctacacgttt
gaagaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaaccatgcc
attgccgcagtagctgtggccctcaagcaggcctgtagccccatgttccgggaatactcc
ctgcaggttctgaagaatgctcgagccatggctgatgccctgctggagcggggctactcg
ctggtgtctggtggcactgacaaccacctagtgctagtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatctatcacagccaataagaacact
tgtcctggagaccgaagcgccatcacacctgggggcctaaggcttggggccccagccttg
acctctcggcagttccgagaggttgacttccggagagttgtggactttatagatgagggt
gttaacattggcttggaggtgaagagtaagactgccaaactccaggatttcaagtccttc
ctgctcaaagacccagaaataagacatcgtctggctgacctcagacaacgtgtggagcag
tttgccagggctttcccaatgcctggttttcatgagcgctga
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