Manis javanica (Malayan pangolin): 108387496
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Entry
108387496 CDS
T06054
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv02010
ABC transporters
mjv04024
cAMP signaling pathway
mjv04152
AMPK signaling pathway
mjv04530
Tight junction
mjv04971
Gastric acid secretion
mjv04972
Pancreatic secretion
mjv04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
108387496 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
108387496 (CFTR)
04152 AMPK signaling pathway
108387496 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
108387496 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
108387496 (CFTR)
04972 Pancreatic secretion
108387496 (CFTR)
04976 Bile secretion
108387496 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mjv02000
]
108387496 (CFTR)
Enzymes [BR:
mjv01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
108387496 (CFTR)
Transporters [BR:
mjv02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
108387496 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_21
AAA_29
T2SSE
RsgA_GTPase
DO-GTPase2
AAA_16
DUF87
MeaB
MMR_HSR1
NACHT
AAA_30
NTPase_1
Zeta_toxin
Intein_splicing
AAA_23
Motif
Other DBs
NCBI-GeneID:
108387496
NCBI-ProteinID:
XP_036879377
LinkDB
All DBs
Position
Unknown
AA seq
1494 aa
AA seq
DB search
MGDLKWYLVLRLHWRPNQVNIYLSHALYFSWTRPILRKGYRQRLELSDIYQIPSSDSADN
LSEKLEREWDRELASKKNPKLINALRRCFFWRFMFYGILLYLGEVTKAVQPLLLGRIIAS
YDPDNKVERSIAIYLGIGLCLLFIVRMLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLS
SRVLDKISIGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWELLQAFTFCGLA
FLIVLALLQAGLGRMMMKYRDQRGGKINERLVITSEMIENIQSVKAYCWEEAMEKIIENL
RQTELKLTRKAAYVRYFNSSAFFFSGFFVVFFSVLPYALIKGIILRKIFTTISYCIVLRM
AVTRQFPWAVQTWYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGYGEL
FEKAKQNNNNRRISNSDNSLFFSNFSLLGAPVLKDINFKIERGQLLAVAGSTGAGKTSLL
MMIMGELEPSEGKIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDEYRYTSVIKACQLEE
DISKFAEKDNIVLGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFE
SCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSKLMGFE
SFDQFSAERRNSILTETLRRFSLEGDAAVTWNETKRQSFKQTGEFGEKRKNSILNPINSI
RKFSIVQKTPLQMNGIEENSDEPLERRLSLVPDSEQGEAILPRSNVINTGPTFQGRRRQS
VLNMMTCSSVNQGQNTHRKKAASTRKMSLAPQANLTETDIYSRRLSQESGLEISEEINEQ
DLKECFFDDLESIPAVTTWNTYLRYLTVHKSLIFVLIWCLVIFLVEVAASLVVLWLLRKT
PPQDKGNSTKNANNSYAVIITSTSSFYVFYIYVGVADTLLALGVFRGLPLVHTLITVSKI
LHHKMLHSVLQAPMSTLNTLKAGAILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAVAV
VSVLQPYIFLATVPVIAAFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRA
FGRQSYFETLFHKTLNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEG
TVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFVDMPTEESKPTKSIKLSKDGQ
LSKVMIIKNQHVNKDDIWPSGGQMIVKDLTAKYTDGGNAILENISFSISPGQRVGLLGRT
GSGKSTLLSALLRLLNTEGEIQVDGVSWDSITLQEWRKAFGVIPQKVFIFSGTFRKNLDP
YGQWNDQEIWTVADEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLSKAKI
LLLDEPSAHLDPITYQVIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENKVRQYES
IQRLLSEKSLFRQAISHSDRLRFFPHRNSSKQKSRSQIAALKEETEEEVQETRL
NT seq
4485 nt
NT seq
+upstream
nt +downstream
nt
atgggagatttgaaatggtatctggttctacgtctacactggagaccaaatcaagtgaat
atttatctttcccatgctctttattttagctggaccagaccaattttgaggaaagggtat
agacaacgcctggaattgtcagacatataccagattccttcttctgattctgctgacaat
ctctctgaaaaactggaaagagaatgggacagagaactggcatcaaagaaaaatccaaaa
ctcattaatgcccttcggcggtgctttttctggagatttatgttctatggaatcttatta
tatttaggggaagtcaccaaagcagtccagcctctcttactgggaagaatcatagcctcc
tatgatccagataacaaggtggagcgctccattgcgatttacctaggcataggcttatgc
cttctcttcattgtgagaatgctgctcctgcacccagccatttttggccttcatcacatt
ggaatgcagatgaggatagctatgtttagtctcatttataagaagactttaaagctgtca
agccgtgttctagataaaataagtattggacaacttgttagtctcctttccaacaacctg
aacaaatttgatgaaggacttgcattggcacattttgtgtggatcgctcctttacaagtg
actctcctgatggggctgctctgggagctgctccaggccttcactttctgtgggcttgct
ttcctcatcgtcctcgccctccttcaagccggcttggggagaatgatgatgaagtacaga
gatcagagaggtggaaagatcaatgaaagacttgtgatcacctcagaaatgattgaaaat
attcagtctgttaaggcatactgctgggaggaagcaatggaaaaaattattgaaaacctg
agacaaacagaactgaaactgacccggaaggcagcctacgtgagatacttcaacagctca
gccttcttcttctcgggattctttgtggtgtttttttctgtgcttccctatgcactgatc
aaaggaatcatccttcgaaaaatattcacaaccatctcctactgcattgttctgcgcatg
gcagtcacccggcagttcccctgggctgtgcaaacatggtatgactctcttggagcaatt
aacaaaatacaggatttcttacaaaagcaggagtataagacattggaatataacttaaca
actacagaagtagtgatggagaatgtaacagccttctgggaggagggatatggggaatta
tttgagaaagcaaaacaaaacaataataatagaagaatttccaacagtgataacagtctc
ttcttcagtaacttctcactccttggtgctcctgtcctgaaagatatcaatttcaagata
gaaagaggacagttgctggcagttgctggatccactggagcaggcaagacttcacttcta
atgatgattatgggagaactggagccttcagagggtaaaattaagcacagtggaagaatt
tcattctgctctcagttttcctggattatgcctggcaccattaaggaaaacatcatcttc
ggtgtttcctatgatgaatatagatacacaagtgtcatcaaagcctgccagctagaagag
gacatttccaagtttgcagagaaggacaatatagttcttggagaaggtggagtcacactg
agtggaggtcagagagcaagaatttctttagcaagagcagtatacaaagatgctgattta
tacctactagactccccttttggatacttagatgttttaacagaaaaagaaatatttgaa
agctgtgtctgtaagttgatggctaacaaaactaggattttggtcacttctaaaatggaa
catttaaagaaagctgacaaaatattaattttacatgaaggtagcagctatttttatggg
acattttctgaattacaaaatctacggcctgacttcagctcaaagctcatgggatttgag
tctttcgaccagtttagtgcagaaagaagaaattcaatcctaacagagacgttaaggcgt
ttctcattagaaggagatgctgctgtcacctggaatgaaacaaaaagacaatcttttaaa
cagactggagagtttggtgaaaaaaggaagaactctattcttaatccaatcaactctata
aggaaattttcaattgtacaaaagactccattacaaatgaatggcattgaagaaaattct
gatgagcctttagagagaaggttgtccttagttccagattctgagcagggagaggctatt
ctgcctcgaagcaacgtgatcaacactggccccacgtttcagggacgaaggaggcagtca
gttctgaatatgatgacatgctcctcagtgaaccaaggtcagaacactcaccgaaagaaa
gcagcatccacacggaaaatgtcactggcccctcaggcaaacttaactgaaacggatata
tattcaaggcggttatctcaagagagtggcttggaaataagtgaagaaattaatgaacaa
gatttaaaggagtgtttttttgatgacttggagagcataccagcagtgactacatggaac
acataccttcgatatctcactgtccataagagtttaatttttgtgcttatttggtgctta
gttatttttctggttgaggtggctgcttctttggttgtgttgtggctacttagaaaaaca
ccccctcaagacaaggggaatagtactaagaatgcaaataacagttacgcagtgatcatc
accagcaccagctcattttatgttttttacatctatgtgggagtagctgacactttgcta
gccctgggagtcttcagaggtttaccactggtgcacactctaatcacagtatcgaagatt
ttacaccacaaaatgttacattctgttcttcaagcacctatgtcaaccctcaacacgttg
aaagcaggtgcaattcttaatagattctccaaagatatagcaattttggatgatcttctg
cctcttaccatatttgacttcatccagctgttattaattgtgattggagcggtggcagtt
gtctcagttttacaaccttacatcttcctggcaacagtgccagtgatagctgcttttatt
ctgctgagagcctacttcctccatacctcacagcaactcaaacaactggaatctgaaggc
aggagtcctattttcactcatcttgttacaagcttgaaaggactgtggacactacgtgcc
tttggacggcagtcttactttgaaactttgttccacaaaactctgaatttacatactgcc
aactggttcttgtacctgtcaacactgcgctggttccaaatgaggatagaaatgattttt
gtcatcttcttcattgctgttaccttcatatccattttgacaacaggtgaaggagaagga
acagttggcattattctaactttagccatgaatatcatgagtacattgcagtgggctgta
aattccagcatagatgtggatagcttgatgcgatctgtgagccgagtcttcaagtttgtt
gacatgccgacagaagaaagtaagcctactaagtcaatcaaactatcaaaagatggccag
ctgtcaaaagttatgattatcaagaaccaacatgtgaacaaagatgacatctggccctca
ggaggccaaatgattgtcaaagatctcacagcgaaatacacagatggtgggaatgccata
ttagagaacatttccttctccattagtcctggacagagggtcggcctcttgggaagaacg
ggatcagggaagagtactttgttatcagccttgttgagactgttgaacactgaaggagaa
atccaagtagatggggtgtcttgggattcaataactttgcaagagtggaggaaagccttt
ggagtcatccctcagaaagtatttatcttttctggaacattcagaaaaaacttggatccc
tatggacagtggaatgatcaagaaatatggacagttgcagatgaggttggactcagatca
gtgatagagcaatttcctgggaagcttgattttgtccttgtggatgggggatatgtccta
agccatggccacaagcagttgatgtgcttggccagatccgttctcagcaaggcaaagatc
ttgctgcttgacgaacccagtgctcatttggatccaataacatatcaagtcatccgaaga
accctaaaacaagcatttgctgattgcacggtaatcctctgtgaacacaggatagaagca
atgttggaatgccaacgatttttggtcatagaggagaacaaagtgcggcagtacgagtcc
atccagaggctgctaagcgagaagagcctcttccggcaggccatcagccactctgaccgg
ctgaggttcttcccgcaccgcaactccagcaagcagaagtctcggtcccaaatcgctgcc
ttgaaggaggagacggaagaagaggtgcaagaaacaagactttag
DBGET
integrated database retrieval system
