Manis javanica (Malayan pangolin): 108390012
Help
Entry
108390012 CDS
T06054
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01521
EGFR tyrosine kinase inhibitor resistance
mjv01522
Endocrine resistance
mjv01524
Platinum drug resistance
mjv04010
MAPK signaling pathway
mjv04012
ErbB signaling pathway
mjv04020
Calcium signaling pathway
mjv04066
HIF-1 signaling pathway
mjv04151
PI3K-Akt signaling pathway
mjv04510
Focal adhesion
mjv04518
Integrin signaling
mjv04520
Adherens junction
mjv04530
Tight junction
mjv05200
Pathways in cancer
mjv05205
Proteoglycans in cancer
mjv05206
MicroRNAs in cancer
mjv05212
Pancreatic cancer
mjv05213
Endometrial cancer
mjv05215
Prostate cancer
mjv05219
Bladder cancer
mjv05223
Non-small cell lung cancer
mjv05224
Breast cancer
mjv05226
Gastric cancer
mjv05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108390012 (ERBB2)
04012 ErbB signaling pathway
108390012 (ERBB2)
04066 HIF-1 signaling pathway
108390012 (ERBB2)
04020 Calcium signaling pathway
108390012 (ERBB2)
04151 PI3K-Akt signaling pathway
108390012 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
108390012 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
108390012 (ERBB2)
04520 Adherens junction
108390012 (ERBB2)
04530 Tight junction
108390012 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108390012 (ERBB2)
05206 MicroRNAs in cancer
108390012 (ERBB2)
05205 Proteoglycans in cancer
108390012 (ERBB2)
05230 Central carbon metabolism in cancer
108390012 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
108390012 (ERBB2)
05226 Gastric cancer
108390012 (ERBB2)
05219 Bladder cancer
108390012 (ERBB2)
05215 Prostate cancer
108390012 (ERBB2)
05213 Endometrial cancer
108390012 (ERBB2)
05224 Breast cancer
108390012 (ERBB2)
05223 Non-small cell lung cancer
108390012 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108390012 (ERBB2)
01524 Platinum drug resistance
108390012 (ERBB2)
01522 Endocrine resistance
108390012 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108390012 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mjv04147
]
108390012 (ERBB2)
04090 CD molecules [BR:
mjv04090
]
108390012 (ERBB2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
108390012 (ERBB2)
Protein kinases [BR:
mjv01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
108390012 (ERBB2)
Exosome [BR:
mjv04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
108390012 (ERBB2)
CD molecules [BR:
mjv04090
]
Proteins
108390012 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
RIFIN
EphA2_TM
Motif
Other DBs
NCBI-GeneID:
108390012
NCBI-ProteinID:
XP_017504077
LinkDB
All DBs
Position
4:159360354..159381798
Genome browser
AA seq
1261 aa
AA seq
DB search
MELAAWYRWGLLLALLPPGAAGTQVCTGTDMKLQLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPASASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIIRGTHLFEDNYALAVLDNG
DLLDSATPATGAAPGGLRELQLRSLTEILKGGVLIQRNLQLCHQDTVLWKDIFHKNNQLA
LTLIDTNSSRTCQPCSPACKTSHCWGESSEDCQSLTRTVCASGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPVNNQEVTSEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFKGDPASSTAPLQPEQLRVFETLEEITGYLYISAWPDSLS
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLHSLRELGSGLALIHRNAHLCFVHTV
PWDQLFRNPHQALLHSANRPEDECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLKGLPREYVKDRNCLPCHPECQPQNGSVTCFGSEANQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGMCQPCPTNCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLFVVIGLVLVLLIKRKRQKNRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPSSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAAGAGGTAHRRHRSSSTRSGGGELTLGLEHSEEEEPPKSPLTPSE
GAGSDVFDGELGMGTAKGLQSLPQHDPSSLQRYSEDPTVLLLPETDGYVAPLTCSPQPEY
VNQPEVRPQPPSPLEGPLSPCRPAGATLERPKTLSPKTLSHGKNGVVKDIFAFGSAVENP
EYLAPRGRAAPQPHTLPAFSPAFDNLYYWDQDPSDRGSPPSTFEGTPTVENPEYLGLDAP
V
NT seq
3786 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtaccgctgggggctcctccttgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcagctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggttgtcaggtggtacagggtaacctg
gagctcacctacctgcctgccagtgccagcctctccttcctgcaggatatccaggaggtc
cagggctatgtgctcatcgcccacaaccaagtgagacaggtcccgctgcagaggctgcga
atcatacgaggcacccatctctttgaggacaactatgccctggccgtgcttgacaatgga
gacctgctagatagtgccacccccgctacaggggctgccccggggggactgcgggagctg
cagctgcgaagcctcacagagatcttgaagggaggggtcttgatccagcggaaccttcag
ctctgccaccaggacaccgttttgtggaaggacatcttccacaagaacaaccagctggcc
ctcacgctgatagacaccaacagctcacggacctgccaaccctgttctccagcttgtaag
acctcccactgctggggagagagttccgaggactgtcagagcttgacgcgaactgtctgt
gccagtggctgtgcccgctgcaagggcccgctgcccacagactgttgccatgagcaatgt
gctgctggctgcacgggccccaaacactccgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacacgtttgag
tccatgcctaaccctgagggccgttacaccttcggcgccagctgtgtgaccacctgtccc
tacaactacctgtctacggatgtggggtcctgcaccctggtctgccctgtgaacaaccaa
gaggtgacatctgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcagtcaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttcttccagagagc
tttaagggggacccagcctccagcacggctcccctgcagcctgagcagctcagagtgttt
gagactctggaggagatcacaggttacctgtacatctcggcgtggccagacagcctgtct
aacctcagtgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcactgaccctgcaagggctaggcatcagctggctggggctgcactccctgcgagaa
ctgggcagtggcctggccctcatccaccgcaatgcccacctctgcttcgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtgccaaccggcca
gaggatgagtgtgtgggtgagggcctggcctgctacccactgtgcgcccacgggcactgc
tggggtccggggcccacccagtgtgtcaactgcagccagttccttcgtggccaggagtgc
gtggaggaatgccgagtactgaaggggcttccccgggagtacgtgaaggacaggaactgt
ctgccgtgccaccctgagtgtcagccccagaatggctcagtgacctgctttggatcggag
gccaaccagtgtgtggcctgcgcccactacaaggaccctcccttctgcgttgctcgctgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagttcccagatgaggag
ggcatgtgccagccatgccccaccaactgcacccactcctgtgtggacctggatgacaag
ggttgccctgctgagcagagagccagccctgtgacatccatcattgctgctgtggtgggc
attctgctgttcgtggtcatagggctggtcctggtcctcctaattaagcgaaagcggcag
aagaaccgcaagtacacgatgcggcggctgctgcaggaaactgagctggtggagccgctg
actcctagtggagcaatgcctaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaagtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggatgaagcatatgtgatggctggcgtgggctcccca
tatgtgtcccgcctcctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcttagaccacgtccgagaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggaagtgcgg
cttgtgcacagggacctggctgcccggaacgtgctggttaagagtcccaaccatgtcaag
attacagactttgggctagcacggctgctggatattgatgagacggagtaccacgcagat
gggggcaaggtgcccatcaagtggatggcattggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagttatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttatgatgggatcccagcccgagagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atcgactccgaatgtcggccaaggttccgggagctggtggccgagttctcgcgcatggcc
agggacccccagcgttttgttgtcatccagaatgaggacttgggcccttccagccccttg
gacagcaccttctaccgctcgctgctggaggatgatgacatgggggacctggtagatgct
gaggagtacctagttccccagcagggcttcttctgcccagaccctgcggccggcgctggg
ggcacggcccaccgcaggcaccgtagctcatccaccaggagtggcggtggtgagctgacg
ctggggctggagcactccgaggaggaggagccccccaagtccccactgacaccctcagaa
ggggctggctctgatgtgtttgatggcgagttgggaatggggacagccaaggggctgcag
agcctcccccaacatgaccccagctctctacagcgttatagcgaggaccccacagtactc
ctgctccctgagactgatggctacgttgcccccctcacctgcagcccccagcctgaatat
gtgaaccagccagaagttcggccacaacccccctcacccctagagggccctctgtctcct
tgtcgacctgctggtgccactctggaaaggcccaagactctttccccaaaaaccctctcc
catggaaagaatggggttgtcaaagacatttttgcctttgggagtgccgtggagaaccct
gagtacttggcaccccggggcagggctgcccctcagccccacactctaccagccttcagc
ccagcctttgacaacctctattactgggaccaggacccatcagatcggggctctccaccc
agcacctttgaagggacccctacggtggagaatcctgagtacctgggcctggatgcgcca
gtgtga
DBGET
integrated database retrieval system
