Manis javanica (Malayan pangolin): 108391436
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Entry
108391436 CDS
T06054
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
KO
K04348
serine/threonine-protein phosphatase 2B catalytic subunit [EC:
3.1.3.16
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04010
MAPK signaling pathway
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04114
Oocyte meiosis
mjv04218
Cellular senescence
mjv04310
Wnt signaling pathway
mjv04360
Axon guidance
mjv04370
VEGF signaling pathway
mjv04380
Osteoclast differentiation
mjv04625
C-type lectin receptor signaling pathway
mjv04650
Natural killer cell mediated cytotoxicity
mjv04658
Th1 and Th2 cell differentiation
mjv04659
Th17 cell differentiation
mjv04660
T cell receptor signaling pathway
mjv04662
B cell receptor signaling pathway
mjv04720
Long-term potentiation
mjv04724
Glutamatergic synapse
mjv04728
Dopaminergic synapse
mjv04921
Oxytocin signaling pathway
mjv04922
Glucagon signaling pathway
mjv04924
Renin secretion
mjv05010
Alzheimer disease
mjv05014
Amyotrophic lateral sclerosis
mjv05020
Prion disease
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05031
Amphetamine addiction
mjv05152
Tuberculosis
mjv05163
Human cytomegalovirus infection
mjv05166
Human T-cell leukemia virus 1 infection
mjv05167
Kaposi sarcoma-associated herpesvirus infection
mjv05170
Human immunodeficiency virus 1 infection
mjv05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108391436 (PPP3CA)
04310 Wnt signaling pathway
108391436 (PPP3CA)
04370 VEGF signaling pathway
108391436 (PPP3CA)
04020 Calcium signaling pathway
108391436 (PPP3CA)
04022 cGMP-PKG signaling pathway
108391436 (PPP3CA)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
108391436 (PPP3CA)
04218 Cellular senescence
108391436 (PPP3CA)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
108391436 (PPP3CA)
04650 Natural killer cell mediated cytotoxicity
108391436 (PPP3CA)
04660 T cell receptor signaling pathway
108391436 (PPP3CA)
04658 Th1 and Th2 cell differentiation
108391436 (PPP3CA)
04659 Th17 cell differentiation
108391436 (PPP3CA)
04662 B cell receptor signaling pathway
108391436 (PPP3CA)
09152 Endocrine system
04922 Glucagon signaling pathway
108391436 (PPP3CA)
04921 Oxytocin signaling pathway
108391436 (PPP3CA)
04924 Renin secretion
108391436 (PPP3CA)
09156 Nervous system
04724 Glutamatergic synapse
108391436 (PPP3CA)
04728 Dopaminergic synapse
108391436 (PPP3CA)
04720 Long-term potentiation
108391436 (PPP3CA)
09158 Development and regeneration
04360 Axon guidance
108391436 (PPP3CA)
04380 Osteoclast differentiation
108391436 (PPP3CA)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108391436 (PPP3CA)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
108391436 (PPP3CA)
05170 Human immunodeficiency virus 1 infection
108391436 (PPP3CA)
05163 Human cytomegalovirus infection
108391436 (PPP3CA)
05167 Kaposi sarcoma-associated herpesvirus infection
108391436 (PPP3CA)
09171 Infectious disease: bacterial
05152 Tuberculosis
108391436 (PPP3CA)
09164 Neurodegenerative disease
05010 Alzheimer disease
108391436 (PPP3CA)
05014 Amyotrophic lateral sclerosis
108391436 (PPP3CA)
05020 Prion disease
108391436 (PPP3CA)
05022 Pathways of neurodegeneration - multiple diseases
108391436 (PPP3CA)
09165 Substance dependence
05031 Amphetamine addiction
108391436 (PPP3CA)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108391436 (PPP3CA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mjv01009
]
108391436 (PPP3CA)
Enzymes [BR:
mjv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
108391436 (PPP3CA)
Protein phosphatases and associated proteins [BR:
mjv01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
108391436 (PPP3CA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Metallophos
Motif
Other DBs
NCBI-GeneID:
108391436
NCBI-ProteinID:
XP_036875985
LinkDB
All DBs
Position
Unknown
AA seq
521 aa
AA seq
DB search
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgtccgagcccaaagcaatagaccccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatgggaag
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataataacagagggggcttcaattctccgacaggaaaaaaatttgctggat
atcgatgcaccagtcacagtttgtggtgacatccatggacaattctttgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagaggatacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttt
acgtttaaacaagaatgtaaaataaagtattcagaacgtgtttacgatgcctgtatggat
gcctttgactgcttgcccctggctgccctgatgaaccagcagttcctgtgtgtacacggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aacgagaagactcaggaacatttcactcacaacaccgtcagggggtgttcgtacttctac
agttacccagctgtctgtgagttcctgcagcacaataacttgttatctatactccgagca
catgaagcccaggatgcagggtatcgcatgtataggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtgtacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaacttcatggatgttttcacttggtccctgccatttgttggggaaaaa
gtgactgagatgctggtgaatgtcctaaatatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggagcaacagctgcagcccgcaaagaggtgataaggaacaagatc
cgagcaataggcaaaatggcccgagtgttctcagtgctcagagaagagagtgagagcgtg
ctgacgctgaaaggcttgactcccacgggcatgctccccagcggggtgctttctggaggg
aagcaaacgctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacagcataagatcactagcttcgaggaggccaagggcttagaccgaattaat
gaaaggatgccacctcgcagagatgccatgccctccgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagtaatatt
cagtga
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