Manis javanica (Malayan pangolin): 108391841
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Entry
108391841 CDS
T06054
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00220
Arginine biosynthesis
mjv00330
Arginine and proline metabolism
mjv01100
Metabolic pathways
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04066
HIF-1 signaling pathway
mjv04071
Sphingolipid signaling pathway
mjv04151
PI3K-Akt signaling pathway
mjv04370
VEGF signaling pathway
mjv04371
Apelin signaling pathway
mjv04611
Platelet activation
mjv04915
Estrogen signaling pathway
mjv04921
Oxytocin signaling pathway
mjv04926
Relaxin signaling pathway
mjv04931
Insulin resistance
mjv04933
AGE-RAGE signaling pathway in diabetic complications
mjv05415
Diabetic cardiomyopathy
mjv05417
Lipid and atherosclerosis
mjv05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
108391841 (NOS3)
00330 Arginine and proline metabolism
108391841 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
108391841 (NOS3)
04371 Apelin signaling pathway
108391841 (NOS3)
04066 HIF-1 signaling pathway
108391841 (NOS3)
04020 Calcium signaling pathway
108391841 (NOS3)
04071 Sphingolipid signaling pathway
108391841 (NOS3)
04022 cGMP-PKG signaling pathway
108391841 (NOS3)
04151 PI3K-Akt signaling pathway
108391841 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108391841 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
108391841 (NOS3)
04921 Oxytocin signaling pathway
108391841 (NOS3)
04926 Relaxin signaling pathway
108391841 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108391841 (NOS3)
05418 Fluid shear stress and atherosclerosis
108391841 (NOS3)
05415 Diabetic cardiomyopathy
108391841 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
108391841 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
108391841 (NOS3)
Enzymes [BR:
mjv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
108391841 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DEC-1_N
Motif
Other DBs
NCBI-GeneID:
108391841
NCBI-ProteinID:
XP_036855092
LinkDB
All DBs
Position
Unknown
AA seq
1200 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPAPAPQPALDHSPPLTRAP
EGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPSQAPPPAEQL
LSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVVATGTYQLRESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCSSAQEMFTYICSHVKYATNRGNLRSAITVFPQRSPGRGDFRI
WNSQLVRYAGYRQQDGSVRGDPANVEITELCVQHGWTPGNGRFDVLPLLIQAPDEPPELF
ALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIG
TRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAA
TASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPTFRYQPDPWKGN
AVKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFR
KAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRP
EQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAF
ARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAARDI
FSPRRSWKRQRYRLSAQAEGLQLLPGLTHVHRRKIFQATVLSVENLQSSKSTRATILVRL
NTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGPPPN
WVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQELETLSQDPRRYEEW
KWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHITVAVLAYR
TQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRG
FWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREPNS
PKTYVQDLLRTELATEVHRVLCLERGHLFVCGDVTMATSVLQTVQRILATEGVMELDEAG
DVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPDTPGP
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggtcaggagcctgggccgccctgcggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagcctccccagcacctgagcccagccgg
gcaccagcacctgcaccccagcctgcactagaccacagccccccgctcacccgggcccca
gaggggcccaagttcccccgtgtgaagaactgggaggtgggcagcatcacctacgacacc
ctgagcgcccaggcacagcaggatgggccctgcaccccacgacgctgcctgggctcccta
gtatttccacggaaactgcagagccggccctcccaggcccctccacctgctgagcagctg
ctgagccaggccagggacttcatcaaccagtactacagctccatcaagcggagtggttcc
caggcccatgagcaacggcttcaggaggtggaagctgaggtggtggccacaggcacctac
cagcttcgggagagtgagctggtgttcggggccaagcaggcctggcgcaacgctccacgc
tgtgtgggtcggatccagtgggggaagctgcaggtgttcgatgcccgggattgcagctct
gcgcaggaaatgttcacctacatctgcagtcacgtcaagtacgccaccaaccggggaaac
cttcgctcggccatcacagtgttcccccagcgcagccccggccgtggggacttccgaatc
tggaacagccaactggtgcgctacgcgggctaccggcagcaggacggctccgtgcggggg
gacccggccaacgtggagatcaccgagctctgcgtccagcatggctggacccccggaaac
ggccgcttcgatgtactgcccctgctgatccaggccccagatgagcccccagaactcttt
gccctgccccctgagctggtcctcgaggtgcccttggagcaccccacgctggagtggttc
gcagccctgggcctgcgctggtatgccctcccagcggtgtccaacatgcttctggaaatt
gggggcttagagttccctgcagcccctttcagtggctggtacatgagcactgagatcggc
acgcggaacctgtgtgaccctcaccgctacaacatcctggaggatgtggccgtctgcatg
gacctggatacccggacgacctcttccctgtggaaagacaaggcagcagtggaaatcaac
ttggctgtcctgcacagttaccagctggccaaagtgaccattgtggatcaccatgctgcc
acagcctcctttatgaagcacctggagaatgagcagaaggcgagggggggctgccctgct
gactgggcctggatcgtgccccccatctcgggcagcctcacccccgtcttccatcaagag
atggtcaactatatcctgtcccctacattccgctaccagccagacccctggaaggggaat
gcagtcaagggtgccggcatcaccaggaaaaagacctttaaggaggtggccaatgcagtg
aagatctctgcctcactcatgggcaccgtgatggcaaagcgagtgaaggcaacgatcctg
tatggctccgagaccggcagggcccagagctacgcacagcagctggggaggctcttccgg
aaggctttcgacccccgggtcctgtgcatggatgagtatgacgtggtgtccctcgagcat
gagacgctggtgttggtggtgaccagcacatttgggaatggggatcccccagagaatgga
gagagttttgcagcggccctgatggagatgtcaggcccctacaacagctcccctcggcca
gaacagcacaagagttacaaaatccgcttcaacagcgtctcctgctcagacccactggtg
tcctcctggcggcggaagaggaaggagtccagtaacacagacagcgcaggggcactgggc
accctcaggttctgtgtgttcggcctgggctcccgggcatacccccacttctgtgccttt
gctcgggcggtggacacacggctggaagagctgggcggggagcggctgctgcagctgggc
cagggtgacgagctgtgtggccaggaggaggccttccgcggctgggcccaggccgccttc
caggcctcctgtgaaactttctgtgtgggcgaagatgccaaggctgccgcccgggacatc
ttcagccccagacggagctggaagcgccagaggtaccggctgagtgcccaggctgaaggc
ctccagctgctgccaggcctgacccatgtgcataggaggaagatattccaggctacagtc
ctctccgtggaaaacctgcagagcagcaagtccactcgagccacgattctggtgcgcctg
aacactggaggccaagaggggctccagtaccagccaggggaccacataggcatctgcccg
cccaaccggccaggcctcgtggaggcactgctgagccgcgtggaggatccacctccacca
ggagagcccgtggcagtggaacagctggagaagggcagccctggtggccctccccccaac
tgggtacgggacccccggctgcccccatgcacgctgcgccaggctctcaccttcttcctg
gacatcacttccccgcccagccctcaactccttcgactgctcagcaccctggccgaagag
tccagtgaacagcaggagctggagaccctcagtcaggacccccggcgctatgaggagtgg
aagtggttccgctgccccacgctgctggaagtactggagcagtttccgtcggtggcgctc
cctgctcccctgctcctcacccagctgcccctgctccagccccggtactactctgtcagc
tcagcacccagcgcccacccaggagagatccacatcacagtagctgtgctggcatacaga
acccaggatgggctgggccccctgcactatggagtctgctctacatggctaagccaactc
aagacaggagaccctgtaccctgcttcatccgaggggctccctccttccggctgccgcct
gatcccagcttgccctgcatcctcgtgggccccggtactggcatcgccccctttcgggga
ttttggcaggagcggctgcatgacattgacagcaaaggactgcaacccgcccccatgacc
ttggtgttcggatgccgatgctcccaactcgaccacctttaccgcgacgaagtgcaggat
gcccagcagcgcggggtgtttggtcgcgtcctcacagccttctcccgggaacccaacagt
cctaagacctacgtgcaggacctcctgcggacagagctggcaactgaggtgcaccgcgtg
ctgtgcctcgagcgcggccacttgtttgtctgcggcgatgtcaccatggcaaccagcgtc
ctgcagacggtacagcgtatcctggcgacggagggcgtcatggagctagacgaggccggt
gacgtcatcggcgtgctgcgggatcaacaacgctatcacgaggacattttcgggctcacg
ctgcgcacccaggaggtgacaagccgcatacgcacccagagcttttccctgcaggagcgt
catctgcggggcgcagtaccctgggcattcgatcctcccggcccagacaccccgggcccc
tga
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integrated database retrieval system
