Manis javanica (Malayan pangolin): 108392197
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Entry
108392197 CDS
T06054
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
108392197 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mjv03032
]
108392197 (TOP2A)
03036 Chromosome and associated proteins [BR:
mjv03036
]
108392197 (TOP2A)
Enzymes [BR:
mjv01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
108392197 (TOP2A)
DNA replication proteins [BR:
mjv03032
]
Eukaryotic type
DNA Topoisomerases
108392197 (TOP2A)
Chromosome and associated proteins [BR:
mjv03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
108392197 (TOP2A)
Centrosome formation proteins
Centriole proteins
108392197 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
108392197
NCBI-ProteinID:
XP_017507778
LinkDB
All DBs
Position
Unknown
AA seq
1532 aa
AA seq
DB search
MEVSPLQPVNENMQINKTKKNEDSKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREITFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKVYIPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGKAGQMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALML
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKTHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKNFGSTCQLSEKFIKAATGCGIVESVLNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINSIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRVQFKYSGPEDDAAISLAFSKKHTDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRCLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVRFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENQDSDNEKETERSDSVTDSGPTFNYLLEMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPRKGGKG
KGKKTQMAEVLPSPCGKRVIPQVTVEMKAEAEKKIKKKIKNENNEGGSQEDGMEVEGLKQ
RLEKKPKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESNFDVPPRETEPRRA
KAKTKFTVELDSDEDFSDFDEKDQDEDFVPSDASPPKTKTSPKHSNKELKPQKSATSEEL
EVAGLGADDAGVDPADSPAARFPAETKTLNPVSKKDVKKTAAKSQSSTSTAGVKKRAAPK
GTKKDLGLNSDTSQKPDPPKAKNRRKRKPSTSDDSDSNFEKMISKAAANKKSKGESDDLH
LDLNSALAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4599 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtgaatgaaaatatgcaaatcaacaaaacaaagaaa
aatgaagattctaagaaaagactgtctattgaaagaatctatcaaaagaaaacacaactg
gaacatattttgctccgcccagatacctacattggctctgtggaattagtgacccagcaa
atgtgggtttatgatgaagatgttggcattaactatagagaaatcacatttgttcctggt
ttgtacaaaatctttgatgagattctagtaaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaaggtgtacatcccagccctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggttacggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
actgctagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaaa
gctggtcagatggaactcaagccctttaatggggaagattatacatgtattaccttccac
cctgatttatctaagtttaaaatgcagagcctagacaaagatattgttgcactgatgctc
agaagagcgtatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat
aagctgccagtaaagggattccgtagttatgtagatatgtatttgaaggacaaggtagat
gaaactggcaatccattgaaaattatccatgaacaagtaaaccacagatgggaagtatgt
ttaaccatgagtgaaaaaggcttccagcaaatcagctttgtcaatagcattgctacttcc
aagggtggcagacatgttgactatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaaacacatcaggtgaaaaatcacatg
tggatttttgtgaacgccttaattgaaaacccaacctttgactctcaaacaaaagaaaac
atgactttacaagtcaagaactttggatcaacatgccaattaagtgaaaaattcattaaa
gctgcaactggctgtggtattgtagaaagcgttctgaactgggtgaagtttaaggcccaa
gtccaattaaacaagaaatgttcagctgtaaaacataacagaatcaagggaattccaaaa
cttgatgatgctaatgatgcagggggccgaaactccactgagtgtactcttatcctaact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggtcgggagagacaaa
tacggggtttttcctctcagaggaaaaatgctcaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacagtatcatcaaaattgtgggtcttcagtacaagaaa
aactatgaagacgaagattcgttgaagactcttcgttatgggaaaataatgattatgaca
gatcaggatcaagacggttcccatatcaaaggcttgctgataaattttattcatcacaac
tggccctctcttctgcgacatcgttttctagaggaatttatcactcccattgtaaaggtg
tctaaaaataagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtattacaaaggtctgggcactagcact
tcgaaagaagccaaagaatactttgcagatatgaaaagacatcgtgtccaattcaaatat
tctggtcccgaagatgatgctgcaatcagcctggcctttagcaaaaagcatacagatgat
cgaaaggaatggttaactcatttcatggaggatagaaggcaacggaaattacttggcctt
cctgaggattacttatatggacaaactactacgtatctcacatacaatgacttcattaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttatttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcatatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttgactcggttgttatttccacca
aaagatgatcacacattaaaattcttatacgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctcgtaaatggtgctgaaggaatcggtactgggtgg
tcttgcaaaatccccaattttgatgttcgtgaagttgtgaataacatcaggtgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaatttcaagggtactattgaa
gagctggctccaaatcaatatgtgattagtggtgaagttgccattctcaattccacaacc
attgaaatctcagagctgcccatcagaacatggactcagacatacaaagagcaggtcctg
gaacccatgctgaatggcactgagaagacgccgccactcatcacagattacagggagtac
cacacagacaccaccgtgaggttcgtggtgaagatgaccgaagaaaagctggcagaggca
gagagagctggactacacaaagtcttcaaactccagactagtctcacatgcaactctatg
gtgctttttgaccatgtaggttgtttaaagaaatatgacacggtgttggatattctaaga
gatttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcctagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaggagttaattaaagttctgattcagagg
ggatatgattcagatcctgtgaaggcttggaaagaagcccagcaaaaggttccggatgaa
gaagaaaatcaagacagtgataatgagaaggaaactgaaaggagtgactctgtaacagat
tctggaccaaccttcaactacctccttgaaatgcctctctggtatctcaccaaggaaaag
aaagatgagctgtgcaaactaagaaatgagaaagagcaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaggagctggaggct
gttgaagcaaaggagaaacaagatgaacaagtaggacttcctaggaaaggggggaaagga
aaggggaagaaaacacaaatggctgaagtgttgccttctccatgtggaaaaagagtcatc
ccccaagtgacagtagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
aatgaaaataatgaaggaggctcacaagaggatggtatggaagtagaaggcctgaaacaa
agattagaaaagaaaccgaaaagagaaccaggtaccaagacaaagaaacaaactacattg
ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat
atgagcagtaatgaaagtaattttgatgtgcctccgcgagaaacagagcctcggagagca
aaagcaaaaaccaaattcacagtggagttggattcagatgaagatttctcagattttgat
gaaaaagatcaagatgaagattttgtcccatcagatgctagtccacctaagaccaaaact
tccccaaaacatagcaacaaagaactgaagccgcagaaaagtgccacatcagaagaactg
gaagtagcaggccttggtgcagatgatgctggggtcgatcccgcagactctcctgccgcc
cgtttcccagctgaaactaaaactttaaaccctgtttctaaaaaggatgtgaagaagaca
gcagcaaaaagtcagtcttccacctccactgcaggtgtgaagaaacgggctgcaccaaaa
ggaaccaagaaggatctgggcttaaattctgatacctctcaaaagcctgatcctcccaaa
gccaagaatcgccgcaaaaggaagccatccacttctgatgattctgactctaattttgag
aaaatgatttctaaagcagccgcaaacaagaaatccaagggagagagtgatgacctccat
ctggacttaaactcagctttggctcctcgggcaaaatctggacgggcaaagaaacctata
aagtacctcgaagaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
