Manis javanica (Malayan pangolin): 108393144
Help
Entry
108393144 CDS
T06054
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00230
Purine metabolism
mjv01100
Metabolic pathways
mjv04927
Cortisol synthesis and secretion
mjv04934
Cushing syndrome
mjv05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108393144 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
108393144 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
108393144 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
108393144 (PDE8A)
Enzymes [BR:
mjv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
108393144 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PAS_4
PAS_3
PDE8
DUF5894
PAS_8
Motif
Other DBs
NCBI-GeneID:
108393144
NCBI-ProteinID:
XP_036856441
LinkDB
All DBs
Position
Unknown
AA seq
830 aa
AA seq
DB search
MGCAPSIHVSEGRAAHPGGREAEDAPGGPSLPHGQRTTASLVARGAGLVGSEPRGGSGHG
SSEKAAADVQFGPMRFHPDQLQVLLVFTKEDKQCNGFCRACEKAGFRCTVTKEAQAVLGC
FLDKHHDIVIIDHRNPRQLDAEALCRSIRSSKLSENTIIIGVVRRADREEPSVMPLIAAG
FTRRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSVFTALEKSQEAIEITSEDRIVQY
ANPAFESTMGYQAGELIGKELAEAPVNEKKADLLETVNSCIRIGKEWQGIYHAKKKNGDN
IQQNVKIIPVLGQGGKIRHYVSIIRVCNGNNKAEKITECVQSDTQTDTQSGKHKDRRKSS
LDVRTMASRASEAASQRRPSSAARVHSVTIEAPISKVINIINAAQESSPMPVIEALDRVL
EILRTTELYSPQLGAKDDDPHASALVEGLMSDGLRRLSGNEYVLSTKNLQQVSGSITTPI
TLHDVPPRIARAMENEECWDFDIFELEAATHKRPLIYLGLKMSARFGICEFLNCSETTLR
SWLQIIEANYHSSNPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAATIHDVD
HPGRTNSFLCNAGSELAILYNDTAVLESHHAAVAFQLTTRDDKCNIFKNMERNDYRALRQ
GIIDMVLATEMTRHFEHVNKFVNSINKPLAALEENGETGKDREAINTMLRTPENRTLIKR
MLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQGLPVVMPVFDRHTCSVPKAQI
SFIDYFITDMFDAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPPPE
NT seq
2493 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcgccgagcatccacgtttccgagggccgggcggcgcaccccggcggcagg
gaggccgaggacgcgccgggcgggccgagcctcccgcacggccagcggacgaccgcctcg
ctcgtggcccgcggcgccggcctcgtggggtccgagcctcgtggcggcagcggccacggc
agcagcgagaaggcggcagccgatgtgcagttcggccccatgagatttcatccagatcag
ctccaggtacttttagtgtttaccaaagaagataaacagtgtaatggattctgtagggca
tgtgaaaaggcagggtttcgctgcacagttaccaaggaggcccaggctgtcctaggctgt
ttcctggacaagcatcacgacatcgtcatcatagaccacagaaatccccgacagctggat
gccgaggcgctgtgcaggtctatcagatcatcaaaactctcagaaaacacaattataatc
ggtgtagtacgcagggcggacagagaagagccctctgtgatgcccctcatcgctgctggc
tttacgaggaggtatgtggaaaaccccagtctcatggcctgttacaacgaactgctgcag
ctggagtttggagaggtgcgatcgcagctaaaactcagggcctgtaactcagtgttcacg
gcattagagaaaagtcaggaagcgattgaaatcacaagcgaagaccgcattgtacagtat
gcaaatcctgcatttgaatccacgatgggctatcaggcaggtgaattaatagggaaggag
ttagcggaagcacctgtgaatgaaaaaaaggccgatctgcttgaaactgtaaattcgtgc
atcaggataggcaaggagtggcaaggaatttaccatgccaagaagaaaaatggagataac
atacagcaaaatgtgaagataatacctgtccttggacagggaggaaaaattagacactat
gtgtccattatcagagtgtgcaatggcaacaataaggctgagaaaataactgaatgtgtt
cagtctgacactcaaacagatactcagtcaggcaaacacaaagacaggcgaaagagctcg
ctagacgtcaggactatggcctcacgcgcgagtgaagctgccagccagaggcgaccctct
tccgcggcccgggtacattccgtgacgattgaggcgcccatctccaaggtaatcaatatc
atcaatgctgcccaggagagcagccccatgcctgtgatagaagccttagaccgtgtgctg
gaaatcctaagaaccactgaactgtactcgccacagctgggcgctaaggacgacgaccca
cacgccagcgccctggtcgagggcttgatgtcggatggtttacgacgattatctgggaat
gaatatgttctttcaacaaaaaacctccagcaggtttcaggcagtataaccactcccatc
acccttcacgacgtcccgccgcggatagctcgggccatggaaaatgaggaatgctgggac
tttgatatttttgaactggaggctgccactcataaaaggcctctgatctaccttggtctc
aaaatgtctgctcgcttcggaatctgtgaattcttaaactgctctgagacaacgctgaga
tcatggctgcaaattatcgaagccaattaccattcttctaacccctaccacaattccaca
cattctgctgatgtgcttcacgccactgcgtatttcctctgcaaagagaggataaagcaa
actttagatccagttgatgaggtcgccgccctcattgccgccaccattcacgacgtggac
caccccgggaggaccaactccttcctgtgcaacgcgggtagcgagctggccatcctgtac
aatgacactgccgtgctggagagccaccacgcggccgtggccttccagctgaccacccgg
gatgacaaatgcaacatcttcaaaaacatggagcggaacgactaccgggcgctgcgccag
ggcatcatcgacatggtcttggccacagaaatgacaaggcacttcgagcatgtcaacaaa
tttgtcaacagcatcaacaagcctttggcagccctggaagaaaatggggaaactggtaaa
gatcgggaagccataaacaccatgctcaggactccagagaacaggactctgattaaacgg
atgctgattaagtgcgctgacgtgtccaacccctgccggcccctggagcagtgcattgag
tgggctgcacgcatctcagaagagtatttctctcagacggacgaggagaagcggcagggc
ctgcccgtggtgatgccagtgttcgacaggcacacctgcagcgtccccaaggcccagatc
tccttcatcgattacttcatcacagacatgtttgatgcctgggacgcctttgtagacctg
cctgagttaatgcagcacctcgacaacaactttaaatactggaagggactggatgagatg
aagctcaggagcctccgaccgcctcccgaatag
DBGET
integrated database retrieval system
