KEGG   Manis javanica (Malayan pangolin): 108393155
Entry
108393155         CDS       T06054                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv03015  mRNA surveillance pathway
mjv04022  cGMP-PKG signaling pathway
mjv04024  cAMP signaling pathway
mjv04114  Oocyte meiosis
mjv04218  Cellular senescence
mjv04261  Adrenergic signaling in cardiomyocytes
mjv04270  Vascular smooth muscle contraction
mjv04390  Hippo signaling pathway
mjv04510  Focal adhesion
mjv04611  Platelet activation
mjv04720  Long-term potentiation
mjv04728  Dopaminergic synapse
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04810  Regulation of actin cytoskeleton
mjv04910  Insulin signaling pathway
mjv04921  Oxytocin signaling pathway
mjv04931  Insulin resistance
mjv05031  Amphetamine addiction
mjv05034  Alcoholism
mjv05168  Herpes simplex virus 1 infection
mjv05205  Proteoglycans in cancer
mjv05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    108393155 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    108393155 (PPP1CA)
   04024 cAMP signaling pathway
    108393155 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    108393155 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    108393155 (PPP1CA)
   04218 Cellular senescence
    108393155 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108393155 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108393155 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108393155 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    108393155 (PPP1CA)
   04921 Oxytocin signaling pathway
    108393155 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108393155 (PPP1CA)
   04270 Vascular smooth muscle contraction
    108393155 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    108393155 (PPP1CA)
   04720 Long-term potentiation
    108393155 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108393155 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108393155 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    108393155 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    108393155 (PPP1CA)
   05034 Alcoholism
    108393155 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    108393155 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    108393155 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mjv01009]
    108393155 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mjv03021]
    108393155 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:mjv03019]
    108393155 (PPP1CA)
   03041 Spliceosome [BR:mjv03041]
    108393155 (PPP1CA)
Enzymes [BR:mjv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     108393155 (PPP1CA)
Protein phosphatases and associated proteins [BR:mjv01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     108393155 (PPP1CA)
Transcription machinery [BR:mjv03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     108393155 (PPP1CA)
Messenger RNA biogenesis [BR:mjv03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     108393155 (PPP1CA)
Spliceosome [BR:mjv03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    108393155 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 108393155
NCBI-ProteinID: XP_017509280
LinkDB
Position
Unknown
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKVKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaaactcaacctggactctattatcgggcgcctgctggaagtgcag
ggctcgaggcctggaaagaatgtgcagctgacagagaacgagatacgtggtctgtgcctc
aaatcccgggagattttcctgagccagccaattcttctggagctggaggcacccctcaag
atctgtggtgacatccacggccagtactacgaccttctgcggctgttcgagtacggcggc
tttcctccagagagcaactacctcttcctgggggactatgtggaccggggcaagcagtct
ctggagaccatctgcctgctgctggcctataaaatcaagtacccagagaacttcttcctg
ctccgtgggaaccatgagtgtgccagcatcaaccggatctacggtttctatgatgagtgc
aagagacgctacaacattaaactgtggaaaacctttaccgactgcttcaactgcctgccc
attgctgccatcgtggacgagaagatcttctgctgccacggaggcctatctccagacctg
cagtccatggagcagattcggcgtatcatgcggcccacagacgtacctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtgtcctttactttcggggctgaggtggtggccaagttcctgcacaagcatgac
ttggacctcatctgccgggcgcaccaggtggtagaagatggctacgaattctttgccaag
cgacagctggtcacactcttctcagctcccaactactgtggcgagtttgacaatgcgggc
gccatgatgagtgtggacgagacactcatgtgctccttccagatcctcaagccagccgac
aagaacaaggggaaatatgggcagttcagtggcctgaaccctggagggcggcccatcacc
ccaccccgcaactccgccaaagtcaagaaatag

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