Manis javanica (Malayan pangolin): 108393532
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Entry
108393532 CDS
T06054
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00562
Inositol phosphate metabolism
mjv01100
Metabolic pathways
mjv04014
Ras signaling pathway
mjv04015
Rap1 signaling pathway
mjv04020
Calcium signaling pathway
mjv04024
cAMP signaling pathway
mjv04070
Phosphatidylinositol signaling system
mjv04919
Thyroid hormone signaling pathway
mjv04933
AGE-RAGE signaling pathway in diabetic complications
mjv05205
Proteoglycans in cancer
Module
mjv_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
108393532 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
108393532 (PLCE1)
04015 Rap1 signaling pathway
108393532 (PLCE1)
04020 Calcium signaling pathway
108393532 (PLCE1)
04070 Phosphatidylinositol signaling system
108393532 (PLCE1)
04024 cAMP signaling pathway
108393532 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108393532 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
108393532 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
108393532 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mjv04131
]
108393532 (PLCE1)
Enzymes [BR:
mjv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
108393532 (PLCE1)
Membrane trafficking [BR:
mjv04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
108393532 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
108393532 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
108393532
NCBI-ProteinID:
XP_036871552
LinkDB
All DBs
Position
Unknown
AA seq
2300 aa
AA seq
DB search
MTSEEMATSVLIPVTQRKMISAQLAIDESSEKVSDISVPKVHPGRQSEQTSHTISQLNKF
KEESSGSSLPKILSIAREKTVSDKNSNGKCWENSMPDSVKNLNINCNNILKSHQRGLPQS
QFYETCDSVTEEGLCLETGNPSSLERKVFPGIQLEIDRPPMGISTLGNQAEVIEMGKAHP
DSNMAVFHFHYEVDKRMSDTFCTLSDNLILDDCGNCISLASVGGEQKKNYMAYTCKLMGL
AKNCNNGQLQCDHCDTLNDKYLCFEGSCQKANVVCSSDSFCREDFTESPPAETFLSHFED
FPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLEAWS
YIDQKRTGFLLPHGRVKEQLSTVVIRQDGSQCLSEAQWYPIYTAVRRGEETEDTIASLLH
FFTKLPGSETAHGRISIGPCLKNCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARS
GLLSTFGGSTGRMMLKERQPGTSVANSSALPSSSAGISKELLDLQPLIQFPEEVASTLME
QEQNIYRRVLPVDYLCFLTRGLGTSEYQTSLPCLRASISASILTSQNGEHNALEDLVMRF
NEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQ
FMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGAS
GLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSL
ETEEEDGPSEGSSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDPHGLEEPQKAFNH
GTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDSSTLTWIKPTTASP
AITKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNK
LGSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTANMLFSGLLELTRAVRKMRKFPDQRQQ
WLRKQYVSFYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNAQRNNTLGI
STTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDANEQEESEVNAIMSPP
HPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMK
GFQSFMISDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCNQAGSESVPLYTNLTID
ENSSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGI
FGVGILQLNDFLVNCQGEHCSYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFA
SKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCW
DGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIF
KTVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLAS
LQAQAYNGGTGTPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNE
EIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLS
TLNASGSSRGKERKSRKSIFGNNPGRMSPGEAASFNKASGKSSYEGMRQAWEESSIPLNP
TTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNP
LMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLER
DLDNMEPTIYSLTIVSGQNVCPSNSTGSPCIEVDILGMPLDSCHFRTKPIHRNTLNPMWN
EQFLFRVHFEELIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSL
FINSRRMEENSSSNTMPASLMFSTEERKCLQSHRVTVHGAPGPEPFTVFSINGGTKAKQL
LQQILTIEQDTKPIATDYFLMEEKYFISKEKIECRKQPFQRAIGPEEEIMQILNSWFPEE
GYVGRIVLKTQQESLEEKTIVQDDKEVILSSEESFFVQVHDVSPEQPRTVIKAPRVSTAQ
DVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTINKKSSIPKSSQRVLLDQECVFQAQ
SKWKGAGKFILKLKEQVQASREDKRKGVSFASELKKLTKSTKQPRGPTSPSQVLASESVQ
NKEEKSMGCMSSSDTIDYRQ
NT seq
6903 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcaacctctgttctcattcctgtgactcagagaaaaatgata
tctgctcagttggctatagatgaaagtagtgaaaaggtctcagacatcagtgttccaaag
gtgcatccaggtaggcagagtgagcagacttctcataccatctcacaactgaacaagttt
aaagaagaatcttctggaagcagcttgcccaagattctctctatagcaagggagaaaaca
gtgagtgataagaatagtaatggaaagtgctgggagaacagcatgccggattctgtgaaa
aaccttaacattaactgtaacaacatactgaaaagccatcagcgtggccttcctcagagc
cagttttatgaaacatgtgattctgtcacagaggaaggcctgtgtttggaaactggaaac
ccttcttcactggaaagaaaggtgttccctggaattcaactggaaatagacagacctccc
atgggcattagtaccttaggaaatcaagcagaggtcatagagatgggcaaggcacaccct
gacagcaacatggcagtatttcactttcattatgaagttgacaaaagaatgtcagatact
ttctgtaccctatcagataacttgattttggatgattgtggaaactgcatatcacttgct
agtgttggtggggagcaaaagaaaaattacatggcatatacttgtaaactgatgggattg
gcaaagaactgtaataatgggcagctgcagtgtgatcattgtgacaccttgaatgacaaa
tacttatgctttgaaggttcttgccaaaaggccaatgtggtatgttcaagtgacagcttt
tgcagggaggattttactgagagtccacctgccgagacctttctgagccattttgaggac
ttccctgataattgtgaagatgtagaggaagacttttttaaaagcaaaaaggagcggtcc
actttgttagtgaggagattttgtaaaaatgatagagaagttaagaaatctgtgtatacc
gggacaagagcaattgtgagaactctgccttctggtcacattgggctggaagcttggagt
tacattgatcagaagagaactggtttcttattgcctcatgggagagtaaaagaacagctg
tcaacagtggtaattaggcaagatgggagtcaatgtctgtcagaagcccagtggtatccg
atctacactgcagtgagaaggggagaagaaacagaagatacaattgcatctctccttcat
ttcttcacaaagctcccaggctctgaaacagcccatggaagaattagcattggtccctgc
ttaaagaattgtgtccgagataccgtgtgtgagtatcgcgccaccctccaaaggacttct
atatctcagtacatcaccggttctctcctagaagcaaccacatctttaggagcaagaagt
ggccttcttagtacttttggaggctccactggacgaatgatgctgaaagaacgtcagcca
ggaacctctgtggccaattccagtgccctcccttcaagttcagctggtatcagtaaggaa
ctgcttgacctacagcccctcatccaattcccagaggaagtcgccagcaccctgatggag
caggagcagaatatttatcgaagggtcttgccggttgactacctttgcttcttgacccgg
ggcttgggcacttcggaataccagacctccctgccctgcctcagagcctccatctcagca
tcgattcttacctcccagaatggagagcacaatgcccttgaagatcttgtgatgagattt
aatgaggtgagctcctgggtgacatggctgatcctcacagcaggctccatggaggagaag
cgagaagtcttctcgtatttggtgcatgtggccaaatgctgctggaacatgggcaactac
aacgctgtcatggaattcttggccggcctcaggtcaagaaaagttttaaaaatgtggcag
tttatggaccagtctgacctggagaccatgaggagcctgaaggatgccatggctcagcac
gaatcttcctgtgaatacaggaaggtggtgacgcgggcgctgcacatccccggctgtaag
gtggtcccgttctgcggcgtgtttctgaaggagctctgtgaagtgctggacggagcctcg
ggcctcatgaagctttgcccgaggtataattcccaagaagaaactctagagtttgtagct
gattacagtggacaagataatttcctgcaacgagtgggacaaaatggcttaaagaattca
gagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagtctg
gagacagaagaggaggacggccccagtgaagggagcagctctaggaaaaattccttgaag
gataaagcccgatggcagtttataattggagatttgttagattctgaaaatgacatcttt
gagcaacccaaagagtgggaccctcatggattggaagagccacagaaggcctttaaccat
gggacagagctcattccatggtacgtgttgtccatccgagctgatgtgcaccagttcctg
ctgcaaggggccacggtcatccactatgaccaggacacgcacctctctgcccgctgcttc
ctccagcttcagcctgacagtagcaccttgacctggataaagcccaccactgcctcccca
gccattactaaagcaaaacttggtgtgctaagtaacacatctgagcctggcaaattccca
ttactgggcaatgctggattaagcggcctggtggagggagttttggatctgttctcagca
aaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaacaaa
ctgggcagcatgcttctctcagagactggtgtgacactgctctatgggcttcagaccaca
gacaatagattactgcactttgtggcaccaaaacatacagctaacatgctcttcagtgga
ttattggaacttactagagccgtgagaaagatgagaaagttccctgaccaaaggcaacag
tggctgcggaaacaatatgtcagcttctatcaggaagatggaaggtatgaagggccaact
ttggctcatgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccct
gggacatcagcaaaaagtgctgagaaacccaatgcacagagaaacaacaccttgggcata
agcaccaccaagaaaaagaagaaaatccttatgaggggtgagagcggagaggtgaccgat
gatgaaatggccacccggaaggccaaaatgcacaaagagtgccggagccggagtggttct
gatcctcaagatgctaatgagcaagaagaatcagaagtgaatgccatcatgagccctcct
caccccctcccttccagaagagcccactcgttgaccacagctgggtcccctaatttggct
gccgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaacaag
agcccatccagtgcttggagcagcagcagctggcacgggcggatcaaaggaggaatgaag
ggctttcagagcttcatgatttcagacagtaacatgagttttgttgaatttgttgagctc
ttcaaatcattcagtgtaaggagccgaaaggacctaaaggatctctttgacatctatgct
gtgccctgcaaccaagccggctccgagtcggtcccactctacaccaacctaaccattgac
gagaactccagtggtcttcagcctgacctagatttgttgaccagaaatgtctcggatttg
gggttgttcattaagagcaaacagcagctatcagataaccagaggcagatatctgatgcc
attgctgccgcgagtattgtgacaaacggcactggggtcgagagcacatccctgggcata
ttcggggttggcatcctccagctcaatgacttcctcgtgaattgccaaggagaacactgc
tcttacgatgaaatcctcagcatcattcagaagttcgagcctagtgttagtatgtgtcat
cagggcctaatgtcttttgaagggtttgcaaggtttctgatggataaagataattttgcc
tccaaaaatgatgagtcacaagagaacattaaagaattacagctgcccctctcctactac
tatattgaatcttcacataatacctacctcacaggccatcagctcaaaggagaatcctca
gtagaactctacagccaggtcctcctgcaaggctgtaggagcatagagttggactgctgg
gatggagatgacgggatgcccatcatttatcatggacatacactgaccaccaagatcccc
ttcaaggaagtggttgaagccattgaccgcagtgccttcatcaactctgacctgcctatc
attatatcaattgagaaccactgctcgttgcctcagcaacgaaaaatggcagaaattttc
aagactgtgtttggagaaaaactcgtggctaaattcttatttgagactgatttctcagat
gatccaatgcttccctcacctgaccaacttagaaggaaagtacttcttaaaaataagaaa
ctaaaagcccatcagacaccagtggatatattaaaacaaaaggctcatcagttagcatcc
ctgcaagctcaggcctataatggggggactggcacgccaccacctgctaataatgaggaa
gaggaagatgaggaggacgaatatgattatgactatgaatccctctctgatgacaacatt
ctagaagacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtataatgaa
gaaatccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtttat
gacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagcagacagatt
gcacctgagctttctgaccttgttatctattgccaagcagtaaaatttccaggcctgtca
actctaaatgcatctggctctagcagaggaaaagaaagaaaaagcaggaagtccattttt
ggcaacaatccgggcagaatgagccctggggaggcagcatcatttaacaaagcatctgga
aaaagttcctatgaaggaatgcggcaggcctgggaggaatcttctatccctctcaaccca
accacgtccctcagcgctatcattagaactcccaaatgttaccatatctcatcactgaat
gaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcc
tgccagctgctgaggacttacccagctgccacccgcatcgattcttccaaccccaacccc
ctcatgttctggctccatgggatacagctcgtggctctcaactaccagacagatgatctc
cccttacatttaaatgctgccatgtttgaggccaatggtggctgtggttatgttttgaaa
cccccagttttgtgggacaagaactgtcccatgtatcagaagttctctcccttagaaaga
gacctggacaacatggagcctaccatctattctttaactattgtctctggccaaaatgtg
tgcccaagtaacagcacaggaagcccatgtattgaagttgatatcctgggcatgcccctg
gacagctgccatttccgcacaaagcccatccatcgaaatactctgaaccccatgtggaac
gaacagtttctcttccgggttcactttgaagagctcatatttcttcgttttgcagttgtg
gaaaacaacagctcagcagtaactgctcaaagaatcattccactcaaggctttaaaacga
gggtatcgacatcttcagctgcgaaacctccacaatgaagtcttagaaatctctagttta
ttcataaacagcagaaggatggaagaaaattcctcaagcaatactatgccggcttctttg
atgtttagtacagaagaaagaaaatgtttgcagagtcacagagtcacagtgcatggggcc
ccagggccagagccctttacagttttctctataaatggaggcaccaaggcaaagcagctt
ctccagcaaattctgaccattgaacaagataccaaacctattgccacagattattttttg
atggaagagaaatattttatatctaaagaaaagattgaatgcagaaaacaaccattccag
agagccattggtccagaagaagagatcatgcagattttaaacagctggtttccagaagag
ggatatgttggcagaattgtcttaaaaacccagcaggaaagcctagaagagaaaaccatt
gttcaagatgataaagaggtgatcttgagctcagaggagagtttctttgttcaagtgcat
gacgtttctccagagcaacctcgaaccgtcatcaaagcgccccgtgtcagcactgcacag
gatgtcattcagcagactttatgcaaagccaagtattcctacagcatcctgagcaacccc
aacccaagtgactatgtgcttttggaagaggtggtgaaagacactatcaacaaaaagtct
tctatcccaaaatcctcccaacgggtccttttggatcaagagtgtgtgtttcaagcccaa
agcaagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggcatcc
cgagaagacaagagaaagggtgtttcttttgcaagtgaactcaagaagctcaccaagtca
acaaaacagccccgaggacccacctcaccttctcaggtcttagcctcagaaagcgtccaa
aacaaggaggagaaatctatgggctgcatgtcctctagtgacaccatagactatcgacag
tga
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integrated database retrieval system
