Manis javanica (Malayan pangolin): 108394025 Help Entry 108394025         CDS       T06054                                  Symbol GCK Name (RefSeq) hexokinase-4   KO K12407   glucokinase [EC:2.7.1.2] Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv00010   Glycolysis / Gluconeogenesis mjv00052   Galactose metabolism mjv00500   Starch and sucrose metabolism mjv00520   Amino sugar and nucleotide sugar metabolism mjv00524   Neomycin, kanamycin and gentamicin biosynthesis mjv01100   Metabolic pathways mjv01200   Carbon metabolism mjv01250   Biosynthesis of nucleotide sugars mjv04910   Insulin signaling pathway mjv04911   Insulin secretion mjv04917   Prolactin signaling pathway mjv04922   Glucagon signaling pathway mjv04930   Type II diabetes mellitus mjv04950   Maturity onset diabetes of the young mjv05230   Central carbon metabolism in cancer Module mjv_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mjv_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:mjv00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     108394025 (GCK)    00052 Galactose metabolism     108394025 (GCK)    00500 Starch and sucrose metabolism     108394025 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     108394025 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     108394025 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     108394025 (GCK)    04922 Glucagon signaling pathway     108394025 (GCK)    04917 Prolactin signaling pathway     108394025 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     108394025 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     108394025 (GCK)    04950 Maturity onset diabetes of the young     108394025 (GCK) Enzymes [BR:mjv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      108394025 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  108394025 NCBI-ProteinID:  XP_017510767 LinkDB All DBs Position Unknown AA seq 458 aa AA seqDB search MESAKKDKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPE GSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWNVKTKHQMYSIPEDAMTGTAEMLFDYIS ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRD AIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQNVELVEGD EGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLYEKLIGGKYMGELVRLVLL KLVDENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLCASAADCDLV RRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHSSV RRLTPSCEITFIESEEGSGRGAALVSAVACKKACLLGQ NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atggagagtgccaagaaggacaaggtggagcagatcctggctgagttccagctgcaggag gaagacctgaagaaggtgatgaggcggatgcagaaggaaatggaccgaggcctgaggctg gagacccacgaggaggccagtgtgaagatgctgcccacctatgtgcgctccacccctgaa ggctcagaagttggggacttcctctccttggacctgggcggcaccaacttccgggtgatg ctggtgaaggtgggggagggggaggcagggcagtggaacgtgaagaccaagcaccagatg tattccatccctgaggatgccatgactggcaccgctgagatgctcttcgattacatctcc gagtgcatctctgactttctggacaagcatcagatgaaacataagaagctgcccttgggc tttaccttttcctttcctgtgaggcacgaagacatcgacaagggtattcttctcaactgg accaagggcttcaaggcctcaggagcagaggggaacaacatcgtgggactcttgagggat gccatcaaacggagaggggactttgaaatggatgtggtggcgatggtgaatgacaccgtg gccacaatgatctcctgctactatgaagaccgccggtgtgaggttggcatgattgtgggc acaggctgcaatgcctgctacatggaggagatgcagaatgtggagctggtggaaggggat gagggccgtatgtgcgtcaacaccgagtggggcgcctttggggactctggcgagctagac gagtttctgctggagtacgaccgcgtggtggatgagaactcgctgaacccaggccagcag ctgtacgagaagctcatcggcggcaaatacatgggcgagctggtgaggctcgtgctgctc aagctcgtggacgaaaacctgctcttccacggggaggcctcggagcagctgcgcacgcgc ggtgccttcgaaacacgcttcgtgtcgcaggtggagagcgactcgggcgaccgcaagcag atctacaacatcctaagcacgttggggctgtgcgcctcggccgccgactgcgacctggtg cgccgcgcctgcgagagcgtgtccacgcgcgccgcgcgcatgtgcgccgcggggctggcg ggcgtcatcaaccgcatgcgggagagccgcagtgaagacgtgatgcgcatcaccgtgggc gtggacggctcggtgtacaagctgcaccccagcttcaaggagcggttccactccagcgtg cgcaggctgacgcccagctgcgagatcaccttcatcgagtccgaggagggcagcggccgg ggcgcggccctggtttctgcggtggcctgtaagaaggcctgcctgctgggccagtga

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