Manis javanica (Malayan pangolin): 108395294
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Entry
108395294 CDS
T06054
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A isoform X1
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv03030
DNA replication
mjv03410
Base excision repair
mjv03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
108395294 (POLE)
03410 Base excision repair
108395294 (POLE)
03420 Nucleotide excision repair
108395294 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mjv03032
]
108395294 (POLE)
03400 DNA repair and recombination proteins [BR:
mjv03400
]
108395294 (POLE)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
108395294 (POLE)
DNA replication proteins [BR:
mjv03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
108395294 (POLE)
DNA repair and recombination proteins [BR:
mjv03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
108395294 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
GARP
Motif
Other DBs
NCBI-GeneID:
108395294
NCBI-ProteinID:
XP_036870223
LinkDB
All DBs
Position
Unknown
AA seq
2277 aa
AA seq
DB search
MVLRGGWRRRVEQGADGEASRDDGPSSSISALKRLERSQWTDKMDLRFGFERLKEPGERT
GWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFSTVEDLVRVRKEISPAVRKNREQ
GRASDAYTSMLSSVLQGGSVIIDEEEMSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
AHWYNIRYRGNAFPVEVTRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGCFCVFNEPDEVHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDSQGEYKAAQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKSKLGYDPVELDPEDMCRMATEQPQILATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFNFLLQRVEKTMRHAIEEEEKVPMEQVTNFQEVC
DQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTPEGSTRAFHELSREEQAKYEK
RRLADYCRKAYKKIHVTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAVEAGDEAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTTVKKPKVTISYPGAMLNIM
VKEGFTNDQYQELAEPASLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPTMRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFIREGRRQVSMAKA
PEDTQSLSAPDMEDFGLAKPLHSTVPMATKRKRVLWESQEESQDLELTVPWQEILGQPPA
LGTSQEEWLVWLRFHKKKWQLQARQRLVRRKRQRLETTKCAPRHGAPREGPTTGLGGFLR
KTAQSILDLPWQIVQISETSQAGLYRLWALISGDLHCFKLSIPRMFYVNQRVAKTEEGPS
YHKVNRVLPRSNMVYNLYEYSVPEDMYQKHINEINTELSAPDIEGVYETQVPLLFRALVQ
LGCVCVVSKQLVRQLSGWEAEPFALEHLEMRSLAQFSYLEPGSIRHIYLYHYMQGHKALF
GIFVPAQRRASVFVLDTVRSNQMPSLSALYSAEHSLLLEKVGSELLPPPKHTFEVRAETD
LKAICRAIQRFLLAYKEERRGPTLIAVQSCWELKRLVSEIPVLEEYPLVPVRVADTISYG
VLDWQRHGARRMICHYLNLDTYLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
NHLLWLSPTLRPDLGGKEADDNRLVMEFNDQATVEINSSGCYSTVCVELDIQNLAVNTIL
QSHHVNDMEGADSMGVSFDVIPQASLEDMITGNQAASAPASYDETALCSSTFRILKSMVV
GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHSMMKKLFLQLIAEFKRLG
SSVVYANFNRVILCTKKRRVEDAIAYVEYITSSVHSKELFHSLTISFSRCWEFLLWMDPS
NYGGVKGIIPSSIHCGQNSQKEGHVEEEKENGDEGDGGQEPDVEELLENNWNILQFLPQA
ASCQSYFLMIISAYIVAVYHSMKEELRRSAPGSTPLRRRGSSQLSQEAQGTSGALPGMIT
FSQDYVANELTQNVFTITQKIQKKVTGSRNSAELSEIFPVLPGSHLLLNNPALEFIKYVC
KVLSLDTNITNQVAKLNRDLLRLADVGEFSEEAQFRDPCRSYVLSEVICRSCNFCQDLDL
CKDSSFSQDGSVLPQWLCSNCQAAYDSSVIEMTLVEALHKKLMAFTLQDLICLKCRGVKE
TNMPVYCSCAGDFALTIHTTVLMEQIGIFRNIAQHYGMSYLMETLEWLLQKNPQLGH
NT seq
6834 nt
NT seq
+upstream
nt +downstream
nt
atggttctgagaggcggctggcggcggcgcgtggaacagggcgcggacggagaggccagt
cgggatgatggcccctcatcctccatttccgcactcaagcgcctggaacgcagtcagtgg
acggataagatggatttgcggtttggttttgagagacttaaggagcctggtgaaaggaca
ggctggctcatcaacatgcaccccactgagattttagatgaagataaacgcttagtcagt
gcagtggattactactttattcaagatgatggcagcagatttaaggtggcgttgccctac
aagccatatttctacattgcaaccagaaaaggttgtgagcgagaagtttcatctttcctc
tctaagaagtttcagggtaaaattgctaaagtagagactgtccctaaagaggatctggac
ttgccaaatcacttagtgggtttgaagcgaaattacattaagctgtccttcagcactgtg
gaggaccttgtcagagtgaggaaggagatctcccctgcggtgaggaagaaccgggagcag
ggccgtgctagtgacgcctacacgtctatgctctccagtgttctgcaagggggtagtgtg
attattgatgaagaggaaatgtccaagaagattgcagaccaactggacaacattgtggac
atgagagagtatgatgttccctaccacatccgcctctccatcgacctgaagatccatgtg
gctcactggtacaacatcagataccgaggaaacgcctttccagtggaagtcacccgccga
gatgaccttgtggaacgacctgaccctgtggttttggcatttgacattgagacgaccaag
ctgcctctcaaatttcctgatgctgagactgaccagattatgatgatttcctatatgatt
gacggtcagggctacctcatcaccaacagggagattgtttcagaagatattgaagatttt
gagttcacccccaagccagaatatgaagggtgcttctgtgtcttcaatgaacctgatgag
gttcatctaatccagagatggtttgagcatgtccaggagactaaacccactatcatggtc
acctacaatggggacttctttgactggccttttgtggaggccagagctgcagtccatgga
ctgagcatgtaccaggagataggattccagaaggacagccagggggagtataaggcagcc
cagtgcatccacatggactgtctcaggtgggtgaagagggacagttaccttccagtgggc
agtcacaacctcaaggcagctgccaaatccaagctgggctatgatcctgtggagctggat
cctgaggatatgtgccggatggccaccgagcagccccagattctggcaacatactctgtg
tcagatgcggtggccacctactacctttacatgaagtatgtccacccctttatatttgcc
ctctgcaccatcatccccatggaacctgatgaggtgctgcggaagggctccggaacacta
tgtgaggccttgctgatggtgcaggccttccacgccaacatcatcttccccaataagcag
gagcaggagttcaacaagctgacggatgacggccatgtgctggatgccgagacctatgtg
ggtggccacgtggaggccctcgaatcaggcgtgttccgcagtgacatcccctgtcgcttc
aggatgaatcctgctgctttcaacttcctgctgcagcgggtagagaagactatgcgtcat
gccattgaggaagaggagaaggtgcccatggagcaggtcaccaacttccaagaggtgtgt
gatcagattaaaaccaagctcacctccctgaaagatgttcctaaccgaatcgaatgtccc
ctcatctaccacctggatgtgggggccatgtaccctaatatcatcctgacaaaccgccta
cagccctctgccatggtggatgaggccacctgtgctgcctgtgacttcaacaagcctgga
gcaaactgccagaggaagatggcctggcagtggaggggcgagttcatgccagccagtcgc
agtgaataccatcggatccagcaccagctggagtcagagaagttccctccattgaccccg
gagggctcaacacgggcttttcatgagctgtcccgcgaagaacaggctaaatatgaaaag
aggagactagcagattactgccggaaggcatataagaagatccatgtgaccaaggtagag
gagcgcctcaccaccatctgccagcgggagaactcattctacgtggacacagtgcgtgcc
ttccgggacaggcgctatgagttcaaaggtctccacaaggtgtggaagaaaaagctctct
gcggctgtggaggcaggcgatgaggcggaagtgaaacgttgcaagaacatggaggtcctg
tatgactcgctgcagctggcacacaagtgcatcctcaactccttctatggctatgtcatg
cgcaaaggggcccgctggtactccatggagatggctggcatcgtctgcttcacgggggcc
aacatcatcacccaagcgcgagagctgatcgaacagatagggaggcccttagagctggat
acagatggaatatggtgtgtcctacccaacagcttccctgaaaattttgtcatcaagacg
actactgtaaaaaagcccaaggtgaccatctcctaccctggtgccatgttaaacatcatg
gtcaaggaaggcttcaccaatgatcagtaccaggagctggctgagcctgcctcgctcacc
tatgtcacccgctcagagaacagcatcttttttgaggttgatgggccctaccttgccatg
atccttccagcctctaaagaagaaggcaagaaactgaagaagagatatgctgtgttcaat
gaggatggttccctggctgagctgaagggcttcgaagtcaaacgccgtggagaactacag
ctgatcaaaatcttccagtcctcggtgttcgaggccttcctcaagggcagcaccctggaa
gaagtatatggctccgttgccaaggtggctgattactggctggatgtgctgtatagcaag
gctgctaacatgcctgattctgagctgtttgagctgatctctgagaaccgttccatgtct
cggaagctggaagattatggggagcagaagtccacatccatcagcacagccaagcgcctg
gccgagttcctgggagaccagatggtaaaagacgcggggctgagctgccgctacatcatc
tcccggaagccggaggggtctccagttacagagagggccatcccacttgccattttccag
gcagagcccacaatgaggaagcactttctccggaagtggctgaagagttcttctcttcaa
gactttgatattcgggcaatcctggactgggactactacattgagcggctgggaagtgcg
atacagaagatcatcaccatacctgcggctctgcagcaggtgaagaacccagtgcctcgt
gtcaaacaccctgactggctgcataaaaagctgctggagaagaatgatgtctataagcag
aagaagatcagtgagcttttcatccgtgaaggcaggagacaggttagcatggccaaggct
ccagaagacacccagagccttagtgctcctgacatggaggactttggccttgcgaagcca
ctgcactcaactgttcccatggctactaagaggaagcgtgtcctctgggagagccaggag
gagtcacaggacctggagctaactgtgccttggcaggaaatcctggggcagcctccggcc
cttggaaccagccaggaagagtggctagtctggctccgcttccacaagaagaagtggcag
ttgcaggcccgccagcggcttgtgcgcaggaagaggcagcgtttggagacaacaaagtgt
gcaccacggcacggggccccccgtgaagggcccactacagggctggggggcttcctgcga
aaaactgcccagagcattttggaccttccatggcagattgtacagatcagtgagaccagc
caggccggcttatacaggctgtgggctcttatcagtggcgacttgcactgcttcaaactg
agcatcccccgcatgttctatgtgaatcagagggtggccaaaacagaggaggggccttca
taccacaaggtgaaccgagtccttcctcgctccaacatggtctacaacctctatgagtac
tccgtgccggaggacatgtaccaaaaacatatcaatgagatcaacactgagctgtccgcc
ccagacattgagggcgtgtatgagacccaggttccattactgttccgggccctagtgcaa
ctgggctgtgtgtgtgtggtcagtaagcagttggtgaggcagctctcaggctgggaagca
gaaccctttgctcttgagcacctggagatgcgctctctggcccagttcagctacttggaa
ccaggaagcatccgccacatctacctgtaccattacatgcagggccacaaagcactcttt
ggcatctttgtgcctgcacagcgcagggcatctgtgtttgtgttggatactgtgcgaagc
aaccagatgcccagcctcagtgccctatactctgctgaacacagcctcttgctggagaaa
gtgggctccgagctcctgcccccccccaaacacacttttgaagttcgagctgaaacagat
ttgaaggccatctgtagagccatccagcgtttcctgctggcctacaaagaggagcgccgc
gggcccaccctcatcgctgttcagtcttgctgggagctgaagaggctagtcagcgagatc
cccgtcttagaggaatatccgctggtacctgtccgtgtggctgatacaatcagctatgga
gtcctggactggcagcgccatggggcccggcgcatgatctgccactacctcaacctggat
acctatctgtcccaggccttcgagatgagcaggtacttccacatccccattgggaatcta
cccgaggacatctccaccttcggctccgacctcttctttgcccgtcatctgcagcgccac
aaccacctgctctggctgtccccaacattgcgccctgatctaggcggaaaggaggctgat
gacaaccgtcttgtcatggagttcaatgaccaagccactgtggagatcaacagttcaggc
tgttactccacagtgtgtgtggagctggacattcagaacctcgccgtcaacaccatcctg
cagtctcaccatgtcaatgacatggagggggctgatagcatgggagtgagcttcgacgtg
atcccgcaggcctccctggaggacatgatcactggcaatcaggccgccagcgccccagcc
agttacgatgagacggctctctgctccagcaccttcaggattctgaagagcatggtggta
ggttgggtaaaggagataacccagtaccataacatctacgccgacaaccaggtgatgcac
ttctaccgctggcttcggtccccatcctcactgctgcatgatcctgccctgcatcgcaca
ctccacagcatgatgaagaagctcttcctgcagctcattgccgagttcaagcgactgggg
tcgtcggtcgtctatgccaacttcaaccgtgtcatcctctgcacgaagaagcggcgggtg
gaggatgccattgcctacgtggagtacatcaccagcagtgtccattctaaagagctattc
cactccttgaccatctccttctcacgatgctgggaatttcttctctggatggacccatct
aactatggaggagtcaaaggaatcattccgtcaagtattcactgtggtcagaactcccaa
aaagagggccatgtggaggaggagaaggagaatggtgacgagggggatggtggccaggag
cctgatgtggaagagttgctggaaaacaactggaacatcctgcagtttctgccacaggct
gcctcttgccagagctacttcctcatgatcatttcagcatacatcgtggccgtctaccat
agcatgaaggaggaactaaggcgcagtgccccagggagcaccccgttgaggaggaggggg
tccagccagctctcccaggaggctcaggggacgtctggagcccttcctggaatgatcaca
ttctctcaagattatgtggcaaatgaacttactcagaatgtcttcaccatcactcagaag
attcagaagaaagtcacaggctctaggaactcggctgagctctcggaaatattcccagtc
ctccctgggtctcacttgctgctcaataaccctgctctggagttcatcaaatatgtgtgc
aaggtcctgtctctggacacgaacatcacaaaccaggtggccaaactgaatcgggacctg
ctgcgccttgcagatgttggcgagttctcggaggaggcccagtttcgggacccctgccgc
tcctatgtgctctctgaggtcatctgccgcagctgtaacttctgccaggacctggacctg
tgcaaagactcctccttctctcaggatgggtctgtgttgcctcagtggctctgttccaac
tgccaggctgcctatgactcatcagtcatcgagatgaccctggtggaagctctgcacaag
aagctgatggccttcaccctgcaggacctgatctgcctgaagtgccgaggtgtgaaggaa
accaacatgcctgtgtactgcagctgtgctggagacttcgccctcaccatccacaccacg
gtcctcatggagcagattggaatcttccggaacattgcccagcactatggcatgtcgtac
ctcatggagaccctggagtggcttctgcagaagaaccctcagctgggccattag
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integrated database retrieval system
