Manis javanica (Malayan pangolin): 108395451
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Entry
108395451 CDS
T06054
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4 isoform X1
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04012
ErbB signaling pathway
mjv04014
Ras signaling pathway
mjv04360
Axon guidance
mjv04510
Focal adhesion
mjv04660
T cell receptor signaling pathway
mjv04810
Regulation of actin cytoskeleton
mjv05170
Human immunodeficiency virus 1 infection
mjv05206
MicroRNAs in cancer
mjv05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
108395451 (PAK4)
04014 Ras signaling pathway
108395451 (PAK4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
108395451 (PAK4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108395451 (PAK4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
108395451 (PAK4)
09158 Development and regeneration
04360 Axon guidance
108395451 (PAK4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
108395451 (PAK4)
09162 Cancer: specific types
05211 Renal cell carcinoma
108395451 (PAK4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108395451 (PAK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108395451 (PAK4)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
108395451 (PAK4)
Protein kinases [BR:
mjv01001
]
Serine/threonine kinases: STE group
STE20 family
108395451 (PAK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
RIO1
KIND
Motif
Other DBs
NCBI-GeneID:
108395451
NCBI-ProteinID:
XP_017513243
LinkDB
All DBs
Position
Unknown
AA seq
589 aa
AA seq
DB search
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRKDSPPPPARVRQENGMPTE
QATTARGGPEKAGSQGRVARHSEAGGGSGDRRRVGPEKRPKSSREGSGVPQESARDKRPL
SGPDVGTPQPPGLASGVKVAAGRPFNTYPRADTDHPSRGAQGEPHNLAPNGPSAGGLAVP
RSSSSRPPARARGPPSPGVLGPHASEPQLAPSARPLTTPAVPPAPGPRSPQREPQRVSHE
QFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLRKQQRREL
LFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCL
AVLQALAVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWM
APELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVS
PSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQNRAR
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaagaagaagaagcgggtagagatctcggcgccatccaactttgaacaccgt
gtgcacacgggctttgaccagcacgagcagaagttcacgggcctgccccgccagtggcag
agcctgattgaggagtccgctcgccggcccaagcccctggtggaccctgcctgcatcacc
tctatccagcccggagcccccaagaccatcgtgcggggcagcaaaggcgccaaggatggg
gccctcacgttgctgctcgacgagtttgagaacatgtcggtgacgcgctccaactccctg
cggaaagacagcccaccaccacctgcccgtgtccgccaggaaaatgggatgcccacagag
caggccaccacggccagagggggcccagagaaggcgggcagccaaggccgggtcgcccgt
cacagcgaggcgggtggtggcagtggtgacaggcgacgggtggggccagagaagaggccc
aagtcttccagggagggctcaggggtaccccaggagtccgcccgggacaagcgccccctc
tctgggcctgatgtcggcaccccccagcctcctggtctggccagtggggtgaaagtggca
gctggccggccctttaacacgtacccgagggctgatacggaccacccgtcccgaggtgcc
cagggggagcctcacaacctggcccccaatgggccatctgcagggggcctggctgttccc
cggtcctcctcctcccggcctcctgcccgagcccgcggcccccccagccctggagtgctg
ggcccccatgcttctgagccccagctagcaccttcagcccgccccctcaccacccctgct
gtcccccctgcccccgggccccgctcaccacagcgggaaccccagcgagtatcccatgag
cagttccgggctgccctgcagctggtggtggatcccggtgacccccgctcctacctggac
aactttatcaagatcggggagggctccacaggtatcgtgtgcattgccaccgtgcgcagc
tcaggcaggctggtggccgtcaagaagatggacctgcgcaagcagcagaggcgtgagctg
ctgttcaatgaggtggtgatcatgagggactaccagcatgagaacgtggtggagatgtac
aacagctacctggtgggggatgagctctgggtggtgatggagttcctggagggaggtgcc
ctcaccgacatcgtcacccacaccaggatgaacgaggagcagatcgccgctgtgtgcctg
gccgtgctgcaggccttggccgtgctccacgcccagggtgtcatccaccgggacatcaag
agtgactccatcctgctgacccacgatggcagagtgaagctgtcagactttgggttctgt
gcccaggtgagcaaggaggtgccacggaggaagtcactggtcggcacaccctactggatg
gccccagagctcatctctcgcctcccctacgggccagaggtggatatctggtctctgggg
gtgatggtgatcgagatggtggatggggagcccccctacttcaacgagccacccctcaaa
gccatgaagatgatccgcgacaacctgccaccccgactgaagaacctgcacaaggtgtca
ccatccctgaagggcttcctggaccgcctgctggtgcgggacccagcccagcgggccacg
gctgctgagctgctgaagcacccgttcctcaccaaagcaggcccacccgccagtatcgtg
cccctcatgcgccagaaccgtgccagatga
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