Manis javanica (Malayan pangolin): 108395479
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Entry
108395479 CDS
T06054
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00260
Glycine, serine and threonine metabolism
mjv00630
Glyoxylate and dicarboxylate metabolism
mjv00670
One carbon pool by folate
mjv01100
Metabolic pathways
mjv01200
Carbon metabolism
mjv01230
Biosynthesis of amino acids
mjv01240
Biosynthesis of cofactors
mjv01523
Antifolate resistance
mjv04981
Folate transport and metabolism
Module
mjv_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
108395479 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
108395479 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
108395479 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
108395479 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
108395479 (SHMT1)
Enzymes [BR:
mjv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
108395479 (SHMT1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
108395479
NCBI-ProteinID:
XP_017513294
LinkDB
All DBs
Position
Unknown
AA seq
517 aa
AA seq
DB search
MIAALHLATISSQQSCKATLNRVMATPVSRAHKDADLWSSHKKMLVQPLKDNDIEVYNII
KKESNRQKVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQ
KRALQVYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDK
KKISATSIFFESMPYKVNPDTGYINYEQLEENARLFHPKLIIAGTSCYSRNLDYARLRKI
AEDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVCTTTHKTLRGCRAGMIFYRRGVRSMD
PKTGKETLYNLESLINSAVFPGLQGGPHNHAIAVFPPGVAVALKQAMTPEFRVYQHQVVA
NCKALAETLMELGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPDPL
YLEGDRSALQPSGLRLGTPALTSRGLLEKDFQKVAQFVHRGIELTLQIQNDVGVKATLKE
FKEKVAGGEKHQEAMRALREEVESFASLFPLPGLPDF
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcagcccttcacctcgctacaatctcctcacaacagagctgcaaggcaactttg
aacagagtgatggcgactccagttagcagagctcacaaggatgctgacctgtggtcctcc
cacaaaaaaatgctggtgcagcccctgaaagacaatgacatcgaggtttacaacataatt
aagaaggagagtaaccggcagaaggttggattggagctgattgcctcagagaattttgcc
agccgagcagttttggaggccctaggctcttgcttaaataacaagtactctgaggggtac
ccaggccagaggtattatggtgggactgagtttattgatgagctggaggtcctctgccag
aagcgagcgctgcaggtctataaactggacccccagtgctggggggtcaatgtccagccc
tactcaggctcccctgcaaacttcgcagtgtacaccgccctggtggaacctcacgggcgc
atcatgggcctggatcttcccgatgggggccatctgacccacgggttcatgacagacaag
aagaaaatctctgctacgtccatcttttttgagtctatgccctataaggtgaacccggac
actggctacatcaactatgagcagctggaggagaatgcccgcctcttccacccgaagctg
attattgcaggaaccagctgctactcccgaaacctggactatgctcgattgcggaagata
gcagaggacaacggggcatacctcatggccgacatggcgcacatcagtgggctggtggct
gctggcgtggtgccctccccgtttgaacactgccatgtggtgtgcaccaccacccacaaa
accctgagaggctgccgtgccggcatgatcttctacaggagaggagtgcgcagcatggat
cccaagactggcaaagagactctgtacaacctggaatcactcatcaactctgccgtgttc
ccaggcctgcaaggaggtccccacaaccacgctattgctgtcttcccgccaggggttgct
gtggccctgaagcaagccatgactccagaattcagagtttatcagcaccaggtggtggcc
aactgcaaggctctggctgagaccttgatggagctgggctacaaagtggtgacaggtggt
tctgacaaccatttaatcctcgtggatctccgatccaaaggcactgatggtggcagagct
gagaaggtgctagaagcctgttctattgcctgcaacaagaacacctgcccagaccctctt
tatcttgaaggtgacagaagtgcactgcagcccagtggactgcgtctggggacccctgca
ctgacatcccgaggacttttggaaaaagacttccaaaaagtagcccaatttgttcacaga
gggatagaactgactctacagatccagaacgacgttggtgtcaaggccaccctgaaggag
tttaaggagaaagtagcagggggtgagaagcaccaagaggccatgagggccctcagggag
gaagtggagagctttgcatctctcttccctctgcccggcctgcctgacttttag
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