Manis javanica (Malayan pangolin): 108396001
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Entry
108396001 CDS
T06054
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04010
MAPK signaling pathway
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04260
Cardiac muscle contraction
mjv04261
Adrenergic signaling in cardiomyocytes
mjv04270
Vascular smooth muscle contraction
mjv04723
Retrograde endocannabinoid signaling
mjv04725
Cholinergic synapse
mjv04726
Serotonergic synapse
mjv04727
GABAergic synapse
mjv04911
Insulin secretion
mjv04912
GnRH signaling pathway
mjv04921
Oxytocin signaling pathway
mjv04924
Renin secretion
mjv04925
Aldosterone synthesis and secretion
mjv04927
Cortisol synthesis and secretion
mjv04929
GnRH secretion
mjv04934
Cushing syndrome
mjv04935
Growth hormone synthesis, secretion and action
mjv05010
Alzheimer disease
mjv05020
Prion disease
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05207
Chemical carcinogenesis - receptor activation
mjv05410
Hypertrophic cardiomyopathy
mjv05412
Arrhythmogenic right ventricular cardiomyopathy
mjv05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108396001 (CACNA1S)
04020 Calcium signaling pathway
108396001 (CACNA1S)
04024 cAMP signaling pathway
108396001 (CACNA1S)
04022 cGMP-PKG signaling pathway
108396001 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
108396001 (CACNA1S)
04929 GnRH secretion
108396001 (CACNA1S)
04912 GnRH signaling pathway
108396001 (CACNA1S)
04921 Oxytocin signaling pathway
108396001 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
108396001 (CACNA1S)
04924 Renin secretion
108396001 (CACNA1S)
04925 Aldosterone synthesis and secretion
108396001 (CACNA1S)
04927 Cortisol synthesis and secretion
108396001 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
108396001 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
108396001 (CACNA1S)
04270 Vascular smooth muscle contraction
108396001 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
108396001 (CACNA1S)
04725 Cholinergic synapse
108396001 (CACNA1S)
04726 Serotonergic synapse
108396001 (CACNA1S)
04723 Retrograde endocannabinoid signaling
108396001 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
108396001 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
108396001 (CACNA1S)
05020 Prion disease
108396001 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
108396001 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
108396001 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
108396001 (CACNA1S)
05414 Dilated cardiomyopathy
108396001 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
108396001 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mjv04040
]
108396001 (CACNA1S)
Ion channels [BR:
mjv04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
108396001 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
108396001
NCBI-ProteinID:
XP_036860614
LinkDB
All DBs
Position
Unknown
AA seq
1859 aa
AA seq
DB search
MEPPSPQDEGLRKKPPKKPVPEVLPRPPRALLCLTLQNPLRKACISVVEWKPFEMIILLT
IFANCVALAVYLPMPEDDNNTLNLSLEKLEYFFLIIFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFTGTDIVATMENE
KPSPCARTGSGRPCTISGSECRGGWPGPNHGITRFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDAEDLREGRLSLDEGGSDTESLYEIEGLNKIVQFVRHWRRWNRV
FRWKCHEVVKSRVFYWLVILIVALNTLSIASEHHSQPLWLTHLQDVANRVLLSLFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCVRLLRIFKVTK
HWTSLSNLVASLLNSVRSIASLLLLLFLFIVISALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALISVFQVLTGEDWNSVMYDGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKPEEEKSMMAKKLEQKPKGEGIPTTAKL
KIDEFESSVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPDASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESMRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDE
SKMTEKECRGYYYVYKDGDPTQMELRPRQWVHNDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDAYEEDTGPVYNHRVEMAVFFITYLILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTLIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIHRTISGDLIAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERTNSLPP
VMANQRPLQFAEIEMEEMESPVFLEDSPRAPNPNLLARANTNNANANVASSVHHERAFPG
ATGAPAAGRGAFSQPTAALGPPGQPWVEKPGQLSQRAVPRAGSPPAPCQRAMAEPPLPGS
WTPTPGPLPEGMAHRSRTQESPSGCQTPVTALLIQEALVQGGPDTWATDADFVMATGQAL
ADACWMEPEEVEVVATEMQRRQESPGGVASALGCPSLGSSLRSLGQKQGSQEALLPTRL
NT seq
5580 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccctcaccccaggacgagggcctgaggaagaagccgccaaagaagcctgtc
ccggaggttctgccgaggccgccccgggccctgctctgcctgacgctgcagaacccgctg
aggaaggcctgcatcagtgtcgtggagtggaaacccttcgagatgatcatcttactcacc
atctttgccaactgtgtggccctggctgtatacctgccaatgcccgaggacgacaacaac
actctgaacctcagcctggagaaactggagtatttcttcctcatcatcttctcgatcgaa
gccgccatgaagatcatcgcctacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggacttcaccatcgtctttctgggggtcttcaccgtgatcctggag
caggtgaacgtcatccagagcaacacagcccccatgagcagcaagggagccggcctggac
gtcaaggccctgagggccttccgcgtgctcagacccctccgcctggtgtcgggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctccccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctacgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgttacttcactgggacagacatcgtggccaccatggagaatgag
aaaccatcgccctgcgccaggacaggttcagggcgcccgtgcaccatcagtggcagcgag
tgccggggcggctggccgggtcccaaccacggcatcacccgctttgacaacttcggcttc
tccatgctcactgtgtaccagtgcatcaccatggagggctggacggacgttctttactgg
gtcaacgatgccattgggaatgagtggccgtggatctattttgtcaccctgattctgctg
gggtccttcttcatcctcaacctcgtcctgggtgtcctgagcggggagttcaccaaggag
cgggagaaggccaagtccaggggcaccttccagaagctccgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacgcagggcgaggtcatggacgccgaggac
ctgagggaaggcaggctgtctttggatgaaggcggttctgacacggagagcctgtatgaa
atcgagggcttgaacaaaatcgtccagtttgtccgacactggaggcggtggaaccgcgtc
tttcgctggaagtgccatgaggtggtgaagtccagggtcttctattggctggtgatcctg
attgtcgccctcaacaccctgtccatcgcctcagagcaccacagccagcctctctggctg
acccatttgcaagacgtcgccaaccgcgtgctgctgtccctcttcaccgtcgagatgctg
atgaagatgtacgggctgggcctgcgtcagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagtggcattctggagatcctcctggtggaatcgggtgccatgacc
cccctgggcatctccgtgctgcgctgcgtccgcctcctgaggatcttcaaggtcaccaag
cactggacgtcgctgagcaacctggtggcatccctgctcaactccgtccgctccatcgcc
tccttgctgctgctgctcttcctcttcatcgtcatctccgccctgctgggcatgcagctc
tttgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaacttcgacagcttc
ccacaggctctcatcagcgtcttccaggttctgacgggtgaggactggaactctgtgatg
tatgacgggatcatggcctacggcggtccgtcctaccccggcatgcttgtgtgcatttat
ttcatcatccttttcgtctgtggcaactacatcctgctcaacgtcttcctggccatcgct
gtggacaacctagccgaggcggagagcctgacctctgcccagaaggccaaggctgaggag
cgaaagcgcaggaagatgtccaggggccttccagacaagccagaggaggagaagtccatg
atggccaagaaactggaacagaaacccaagggggagggtatccccaccaccgccaagctg
aaaatagatgagtttgaatcgagtgtcaatgaggtgaaggacccctacccctcggctgac
ttcccaggggatgatgaagaagatgagccagagatcccggtgagcccccgcccgcgcccc
ctggctgagctgcagctgaaagagaaggcggtgcccattccagatgccagctccttcttc
atcttcagccccaccaacaagatccgtgtcctgtgtcatcgcattgtcaatgccacgtgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgccgccctggctgccgaggac
cccatccgggcagagtccatgaggaatcagatccttgggtattttgacatcgctttcacc
tctgtcttcactgtggagattgtcctcaagatgaccacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcaccatctccgtggtgaagatcctcagggtgctgagg
gtgctccgacccctccgggccatcaacagggccaaagggctgaagcacgtggtgcagtgt
gtgttcgtggccatccgcaccatcggcaacatcgtcctggtcaccactctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgacgag
tccaagatgacagaaaaggagtgcaggggctattactatgtgtacaaggacggggacccc
acgcagatggagctgcgtccccgccagtgggtgcacaacgacttccacttcgacaacgtg
ctctcagccatgatgtcgctcttcactgtctccaccttcgagggatggccccagctactg
tacaaggccatagacgcctacgaggaggacacgggccccgtctacaaccaccgcgtggag
atggccgtcttcttcatcacctacctcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggaacagggcgagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgtgtgcagtatgctctcaaggcccgcccactgcggtgc
tacatccccaagaacccataccagtaccaggtgtggtacgtcgtcacctcctcctacttt
gagtacctgatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccctcatc
ttcaccctggagatgatcctgaagctcatggcgttcaaggccagggggtattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagc
gagatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccgcatctccagcgccttcttccgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggtgtgcgcaccctgctgtggacattc
atcaagtccttccaggctctgccttatgtggctctgctcatcgtcatgctgttcttcatc
tacgcggtcatcggcatgcagatgtttggaaagatcgccttggtggatgggacccaaata
aaccgaaacaacaacttccagaccttcccgcaagctgtgctgcttctcttcaggtgtgca
acaggtgaggcgtggcaggagatcctgctggcctgcagctacggcaagctgtgcgaccct
gagtccgattacgccccaggcgaggagcatacgtgcggcaccaacttcgcctattactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtggccgtcatc
atggacaactttgactacctcactcgggactggtccatcctcggccctcatcacctggac
gagttcaaggccatctgggcagagtatgacccagaggctaagggcagaatcaaacaccta
gacgtggtgaccctgctgagaaggatccagcccccgctgggcttcgggaagttctgccca
caccgggtagcctgtaagcggctggtgggcatgaacatgcccctgaacagtgatggcacg
gtcaccttcaatgccactctcttcgccctggtacgcacggcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaaaatctggaagaga
accagcatgaagctcctggaccaggtcatccctccgataggagatgacgaagtgactgta
ggcaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaggagtattatgggtatcggcccaagaaggacacggtgcagatccaggctggactgcgg
accattgaggaggaggctgctcctgagatccaccgaaccatctcgggggacctgatagct
gaagaggagctggagagagccatggtggaggctgcaatggaggaagggatatttcggagg
actggaggcctctttggccaggtggacagcttcctggaaaggaccaactccctgcccccc
gtcatggccaaccagagacccctccagtttgctgagatagagatggaggagatggaatca
cctgtgttcctggaggactcccctcgagctccaaaccccaaccttcttgctcgtgccaat
actaataatgccaatgccaacgttgcctccagcgtccaccatgaaagggcattccctgga
gcgacaggggcacctgccgccggacgaggagccttcagccaaccaacggcagccttggga
ccccccggccaaccctgggtggagaagccaggacagctgagccagagagcagtgcccaga
gctgggtccccccctgccccctgccagcgtgccatggcggagcctcccctgcctgggagc
tggacccccactccagggcctctgcctgagggaatggcccaccgcagcaggacccaggag
agcccttctggctgccagaccccagtcacggccctgctcatccaggaggctctggtccaa
ggaggcccggacacctgggcaactgatgcggacttcgtcatggcaacaggccaggccctg
gctgatgcctgctggatggagccggaggaagtggaggtggtagcaaccgagatgcagaga
agacaggagtccccgggaggcgtggccagcgccctgggctgtccgagcctcgggtcttct
ctgcgcagcctcggccagaagcagggctcccaggaggcccttctccccaccaggctgtga
DBGET
integrated database retrieval system
