Manis javanica (Malayan pangolin): 108396821
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Entry
108396821 CDS
T06054
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00230
Purine metabolism
mjv00670
One carbon pool by folate
mjv01100
Metabolic pathways
mjv01523
Antifolate resistance
Module
mjv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108396821 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
108396821 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
108396821 (GART)
Enzymes [BR:
mjv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
108396821 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
108396821 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
108396821 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
108396821
NCBI-ProteinID:
XP_017515335
LinkDB
All DBs
Position
Unknown
AA seq
1012 aa
AA seq
DB search
MTARVLVVGNGGREHTLAWKLAQSDHVKQVLVAPGNAGTACSEKISNTGNAISISDHTTL
AQFCKDENIEFIVVGPEAPLAAGIVGNLMSAGVRCFGPTAEAAQLESSKRFAKEFMDRHG
IPTAQWRAFNKPEKAYSFIMSADFPALVVKASGLAAGKGVIVAESKEEACKAVQEIMQNK
AFGAAGETIVIEELLEGEEVSCLCFTDGRSVAPMPAAQDHKRLLEGDHGPNTGGMGAYCP
APQVSKDLLLKIKNTILQRTVDGMRQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPEC
QVILPLLKSDLYEVIQSTLDGQLCTSLPVWHENRTAVTVVMASKGYPGDYTKGVEITGFP
EAQALGLEVFQAGTTLKDGKVVTNGGRVLTVTAIRESLISALEEAKKGLAAIKFEGAIYR
KDIGYRAIALFQQPRGLTYKESGVDIAAGDMLVQKIKPSAKATSRPGCDVDLGGFAGLFD
LRAAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYF
SCGKLDLNTTETVVTGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQK
LPHLERITEGDVIIGVASSGLHSNGFSLVRKIIAKSFLQYSSPAPDGCGDQTLGDILLTP
TRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKLGVDLDAQTWRIPRIFSWLQQ
EGHLSEEEMARTFNCGIGAALVVSKDLTEQILRDIQQHKEEAWVIGRVVACPEGFPRVRV
KHLIDTMQINGSALENGILKNHSFVQPKRARVAVLISGTGSNLQALIDSTREPSSSAHIV
VVVSNNAAVAGLGRAERAGIPTRVINHKLYKSRIEFDTAIDQVLEEFSTDIVCLAGFMRI
LSGPFVRKWNGKMLNIHPSLLPSFKGSKAHEQALAAGVTVTGCTVHFVSEDVDAGQIILQ
EAVPVKRDDTVSTLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVREE
NT seq
3039 nt
NT seq
+upstream
nt +downstream
nt
atgacagcccgagtacttgtcgttggcaatggaggaagggaacatacactggcctggaaa
cttgcacagtctgatcatgtcaaacaggtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatactggtaatgccatctcaatcagtgatcacactaccctt
gctcagttctgcaaagatgagaacattgaattcatagttgttggaccagaagcacctctg
gctgctggaattgttgggaacctgatgtctgcaggagtgcgatgctttggccccacagca
gaagcagctcagttagagtccagcaaaagatttgccaaagagtttatggaccgacatgga
atcccaaccgcacaatggagagctttcaacaaacctgagaaggcctacagcttcattatg
agtgcagacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtg
attgttgcagaaagcaaagaagaggcctgtaaagctgtacaggaaatcatgcagaataaa
gcttttggagcagctggagaaacaattgtcattgaagaactccttgaaggagaagaggtg
tcttgtttgtgcttcactgatgggagatctgtggcccccatgcctgcagcacaggaccat
aaacggttgctggagggagatcatggccccaacacagggggaatgggagcctactgccca
gcacctcaggtttctaaggatttgttgctaaaaataaaaaataccattcttcagaggacg
gtggatggcatgcggcaggagggtatgccatacacaggtgttctctatgctggtataatg
ctgaccaaggatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgc
caagtgatcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagat
ggccagctctgcacatctctgcctgtttggcacgaaaaccgcactgccgtaactgttgtc
atggcaagtaaaggttacccaggagactacaccaagggtgtggaaataacagggtttcct
gaggctcaagctttaggactagaggtgttccaagcaggcactaccctaaaagatggcaaa
gtggtgactaatggaggtagagtccttacagtaacagccatccgggaaagtctcatctca
gcccttgaagaagccaagaaaggactagctgctataaagtttgagggagccatttacagg
aaggacattggctatcgtgccatagctctcttccaacagcccaggggcctgacttacaag
gaatctggggtagacattgcagctggagatatgcttgtccaaaaaattaagccttcagca
aaagccacctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgat
ctgagagcagctggtttcaaagatcctcttctggcctgtggaacagatggtgttggaact
aaactgaagattgcccagcagtgcaacaagcatgataccattggtcaagatttggttgca
atgtgtgtaaatgatattctggcacaaggagcagaacccctcttcttccttgattacttt
tcctgtggaaaacttgacctcaatacaactgaaactgttgtcactggaatcgctaaagct
tgtggaaaagctggatgtgctcttcttggaggtgaaacagcagaaatgcctgacatgtat
ccccctggagagtatgacctagctggttttgctgtgggtgccatggaacgggatcaaaaa
ctccctcacttggaaagaatcaccgaaggggatgttattattggagtggcttcatctggt
ctacacagcaatgggtttagccttgtgaggaaaattattgcaaaatctttcctccagtac
tcctctccagcaccagatggctgtggtgaccagaccttaggggacatacttcttactcca
accagaatttacagccattcactgttacctgtcctacgttcagggcacgtcaaggccttt
gcccatattactggtggaggattgctagaaaacatccccagagtccttcctcagaaactt
ggggtggatttagatgcccagacctggagaatccccaggatcttctcgtggttacagcag
gaaggacatctctctgaagaagagatggccagaacatttaactgtggcattggggctgcc
ctcgtggtatcaaaggatctgacagagcagattctgagggacattcagcagcacaaggaa
gaagcctgggtgattggcagggtggttgcatgtcctgaaggttttcctcgtgtgagagtc
aagcatctgattgacaccatgcaaataaatggatcagctttggagaatggcatcctgaaa
aatcattcatttgtccaaccaaaaagggcaagagtggctgtcttaatatctggaacagga
tctaacctccaagctctcattgacagtactagggaaccaagtagctctgcacacattgtt
gtagttgtctctaacaatgctgctgtggctggcttaggtagagcagaaagagccgggatt
cccaccagagtaattaatcataagttatataaaagtcgtatagaatttgacactgccatt
gaccaagtcctagaagagttctccacagacatagtctgtcttgcaggattcatgagaatt
ttatctggcccctttgtgagaaaatggaatgggaaaatgctcaacatccacccatccttg
cttccatcttttaagggttcaaaagcccatgaacaggccctggctgctggtgtcacagtc
actgggtgcactgtgcactttgtatctgaagatgtggatgctggacaaattattttacaa
gaagctgttcctgtgaagagggatgacacggtttcaactctgtctgaaagagtaaaatta
gcagaacataagatatttcctgcagccctccagctggtggccagtggaactgtacagctg
ggagaaaatggcaagatctgctgggtcagagaggaatga
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