Manis javanica (Malayan pangolin): 108397113
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Entry
108397113 CDS
T06054
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04217
Necroptosis
mjv04380
Osteoclast differentiation
mjv04620
Toll-like receptor signaling pathway
mjv04621
NOD-like receptor signaling pathway
mjv04630
JAK-STAT signaling pathway
mjv04658
Th1 and Th2 cell differentiation
mjv04659
Th17 cell differentiation
mjv05145
Toxoplasmosis
mjv05160
Hepatitis C
mjv05161
Hepatitis B
mjv05162
Measles
mjv05164
Influenza A
mjv05165
Human papillomavirus infection
mjv05167
Kaposi sarcoma-associated herpesvirus infection
mjv05168
Herpes simplex virus 1 infection
mjv05169
Epstein-Barr virus infection
mjv05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
108397113 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
108397113 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
108397113 (TYK2)
04621 NOD-like receptor signaling pathway
108397113 (TYK2)
04658 Th1 and Th2 cell differentiation
108397113 (TYK2)
04659 Th17 cell differentiation
108397113 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
108397113 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
108397113 (TYK2)
05160 Hepatitis C
108397113 (TYK2)
05171 Coronavirus disease - COVID-19
108397113 (TYK2)
05164 Influenza A
108397113 (TYK2)
05162 Measles
108397113 (TYK2)
05168 Herpes simplex virus 1 infection
108397113 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
108397113 (TYK2)
05169 Epstein-Barr virus infection
108397113 (TYK2)
05165 Human papillomavirus infection
108397113 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
108397113 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108397113 (TYK2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108397113 (TYK2)
Protein kinases [BR:
mjv01001
]
Non-receptor tyrosine kinases
JAK family [OT]
108397113 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
108397113
NCBI-ProteinID:
XP_017515850
LinkDB
All DBs
Position
Unknown
AA seq
1220 aa
AA seq
DB search
MGGGVSVAIRWLLPVAAGRGPGFEPESPGKAKPAVKSMPLWHRRPATRASKPDEDETQPL
ATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ
VWLPPNHVLEVSRDISLTLYFRMRFYFRNWHGMNPQEPAVYRCAPPGTEASSEQAEQGVQ
LLDPASFEYLFEQGKHEFVNDVASLWELSNEEEIHHFKNESLGMAFLHLCHFAVCHGVPL
EKVAKKISFKDCIPRSFRLQIQQHNALTRLRLRSIFRRFLQAFQPGRLSQQVIMVKYLAT
LEQLAPRFGTERMPVCHLEPLARAEGEPCYIRDSSRAPPEPQPESAARAPTHEVLVTGTG
GIQWRQMEAEGPRGDGGGSSRNCHAGPFGKKAKAQEVGSQPADRPQEAPWTDFCDFRDIT
HVVLKERHVSVHCQDKCLELTLPSRAAALSLVSLVDGYFRLTADSSHYLCHEVAPPRLVM
SIQDGIHGPLMEPFVLAKLQPEDGLYLIHWSTSHLSRLILTVAQRDQAPGAGCLRLRRFP
IKLQAGVFRLEGWDRSFPSARELRAALQGCSLRTGNDCFSLRRCCLPRPGEISNLIIMRG
PRAKTRPLNLSQLSFHRICQDDITQLSHLGQGTRTNVYEGLLRVGGQGPKEGRADGGDSP
LPSGGRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHVHLAFMHGVCVHGSENIMVT
EFVERGPLDVWLRRERGHVPVAWKVVVAQQLASALSYLEDKSLVHGNVCGRNILLARLGL
AEGTSPFIKLSDPGVGLSVLSREERVERIPWTAPECLSGGANSLSTAADKWGFGATLLEI
CFDGEAPLQGRGPSEKERFYQKQHQLPEPSCPDLATLTSQCLTYEPAQRPSFRTILRDLT
RLQPQNLVDVLAVNPDSSASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV
AVKALKAGCGPQLRRGWRREIDILRTLYHEHIVKYKGCCGDQGEKSVQLVMEYVPLGSLR
DYLPRHSVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA
VPEGHEYYCVREDGDSPVFWYAPECLKECKFYYSSDVWSFGVTMYELLTYCDSSQSPPSK
FIELIGLTQGQMTVLRLTEVLERGERLPRPEKCPCEIYVLMKNCWEADASFRPTFQNLIP
ILKMAHEKYQGQPPSVFSVC
NT seq
3663 nt
NT seq
+upstream
nt +downstream
nt
atgggaggcggtgtctcggtggcgatcagatggctgctgccggtggcagcggggcggggt
cccgggttcgagcctgagtccccgggcaaggccaagccagctgtcaagagcatgccactg
tggcaccggaggcccgccaccagggccagcaagcccgatgaagatgaaactcagcccctg
gccaccagaggtggtctgaaggtccttctgcactgggctggccctggtggtggggagccc
tgggtcaccttcagtgaggccacactgactgcagaggaggtctgcatccacattgcacac
aaagtcggcatcactcctccctgcttcaatctctttgccctctttgatgctcaggcccag
gtctggctgcccccaaaccatgtcctggaggtctccagagacataagcctgacattgtac
ttccgtatgaggttttatttccggaactggcatggcatgaatcctcaggagccggctgtg
tatcgctgtgcacccccagggactgaggcttcctcagaacaggcagagcagggggtgcaa
ctcctggacccagcctcctttgagtacctctttgagcagggcaagcatgagtttgtaaat
gatgtggcatcactgtgggagctgtcaaatgaagaagagatccaccactttaagaacgag
agtctgggcatggcctttcttcacctctgccactttgctgtctgccacggtgttcccctg
gagaaggtggccaagaaaatcagcttcaaggactgcatcccacgctccttccgcctgcag
atccagcagcacaatgcgctgacccggttgcgcctacggagcatcttccgcaggttcctg
caggccttccagccaggccgcctctcccagcaggtcatcatggtcaagtacctggccaca
ctcgagcagctggcgccccgcttcggcacagagcgcatgcccgtgtgccacctggagccg
ctggcccgggcggagggagagccctgctacatccgggacagcagccgggcccctccggag
ccccagcccgagtccgccgccagagcccccacccatgaggtgctggtgacgggcactggt
ggtatccagtggcggcagatggaggcagagggtccccgtggtgatggcgggggcagcagc
cggaattgccatgctggcccatttgggaagaaagctaaggcccaagaggtgggcagccag
ccagcagacaggcctcaggaggcaccgtggactgacttctgtgacttccgggacatcacc
cacgtggtgctgaaagaacgccacgtcagcgtgcactgtcaggacaagtgcctggagctg
accctgccttcccgggctgcagccctgtccttggtgtcgctggtggatggctatttccgc
ctgacagctgactcaagccactacctgtgccacgaggtggcccctccacggctggtgatg
agcatccaggacggcatccacgggcccctgatggagccattcgtgctggccaagctgcag
cctgaggatggcctctacctcatccactggagcaccagccacctcagccgcctcatcctc
acggtggcgcagcgcgaccaggcacctggcgccgggtgcttgcgtctgcgcaggttcccc
atcaagctgcaggctggggtcttcaggctagagggctgggaccggtccttccccagcgcg
cgggagctgcgggctgccctgcaaggctgctcgctgcggaccggcaatgactgcttctcc
ttgcgccgctgctgcctgccacggccaggagaaatctccaatctcatcatcatgcgggga
cctcgggccaaaaccaggccactcaacctcagccagctcagcttccaccggatctgccag
gacgacatcacccagctgtcccacctgggccagggcaccaggaccaacgtgtatgaaggc
ctcttgcgagtggggggccaaggccccaaggagggcagggcagatggtggggactctccc
ttgcccagcgggggccgcgggcaagaactgcgagtggtactcaaggtgctggaccccagc
catcacgacatcgccctggccttctatgagacagccagcctcatgagccaggtctcccac
gtgcacctggccttcatgcatggcgtctgcgtgcatggctccgagaacatcatggtgacg
gagttcgtggagcgtgggcccctggatgtgtggctgcggcgggagaggggccatgtacct
gtggcctggaaggtggtggtggcccagcagctggccagcgccctcagctacctggaagac
aagagcctggttcatggaaatgtgtgtggccggaacatcctgctggcacggctggggctg
gcggaaggcaccagcccattcatcaagctgagtgaccccggagtgggtctgagtgtcctc
tccagggaggagcgggtagagcggatcccctggacagcgcccgagtgcctgtctggtggg
gccaatagcctaagcactgcggctgacaagtggggctttggcgccactctgctggagatc
tgcttcgacggggaggcccccctgcagggccgtggcccctctgagaaagagcgcttctac
cagaagcagcaccagctgccagagccctcttgcccagacctggcaacgctcaccagtcaa
tgcctgacctacgagccggcacagcggccgtctttccgtaccatcctgcgggacctcact
aggctgcagccccagaatctcgttgacgtcttggcggtgaacccggactcgtcagcgtca
gaccccacggtttttcataagcgctatttgaagaagatccgggatctgggcgagggccac
tttggcaaggtcagcctgtactgctacgacccgaccaacgacggcactggcgagatggtg
gccgtcaaggccctcaaggctggctgcgggccccagcttcgcaggggctggaggcgggag
atcgacatcctgcgcacgctgtatcacgagcacatcgtcaagtacaagggctgctgcggg
gatcaaggcgagaaatccgtgcagctcgtcatggagtacgtgcctctgggcagcctccga
gactacctgccccggcacagcgtcgggctggcccagcttctgctcttcgcccagcagatc
tgcgagggcatggcctacctacacgcacagcactacatccatcgcgacctggctgcccgc
aacgtgttgttggacaacgacaggctggtcaagatcggggactttggcctagccaaggct
gtgcctgaaggccatgagtactactgcgtgcgagaggatggggacagccccgtgttctgg
tacgccccagagtgcctaaaggaatgtaagttctactattcatctgacgtctggtctttt
ggagtcaccatgtatgagctcctgacctactgtgactccagtcagagccctccttcgaaa
ttcatcgaactcatcggcctcacgcagggacagatgacggtgctgaggctcaccgaggtg
ctggaacgaggggagaggctgcctcggccggagaaatgtccctgtgagatctacgtcctg
atgaagaactgctgggaggccgacgcctcattccgccccaccttccagaacctcataccc
atcctcaagatggcccacgagaagtaccaaggccagcccccctcagtgttcagcgtgtgc
tga
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integrated database retrieval system
