Manis javanica (Malayan pangolin): 108398314
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Entry
108398314 CDS
T06054
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv03060
Protein export
mjv04141
Protein processing in endoplasmic reticulum
mjv04612
Antigen processing and presentation
mjv04918
Thyroid hormone synthesis
mjv05012
Parkinson disease
mjv05014
Amyotrophic lateral sclerosis
mjv05020
Prion disease
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
108398314 (HSPA5)
04141 Protein processing in endoplasmic reticulum
108398314 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
108398314 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
108398314 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
108398314 (HSPA5)
05014 Amyotrophic lateral sclerosis
108398314 (HSPA5)
05020 Prion disease
108398314 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
108398314 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108398314 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
mjv03110
]
108398314 (HSPA5)
04131 Membrane trafficking [BR:
mjv04131
]
108398314 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mjv04147
]
108398314 (HSPA5)
Enzymes [BR:
mjv01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
108398314 (HSPA5)
Chaperones and folding catalysts [BR:
mjv03110
]
Heat shock proteins
HSP70 / DNAK
108398314 (HSPA5)
Membrane trafficking [BR:
mjv04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
108398314 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
108398314 (HSPA5)
Exosome [BR:
mjv04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
108398314 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
108398314 (HSPA5)
Exosomal proteins of colorectal cancer cells
108398314 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
108398314
NCBI-ProteinID:
XP_017517694
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEDDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEAADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggctgcggtgcttctgctgctcggcgcggcgcgggcggaggag
gacgacaagaaggaggacgtgggcaccgtggtcggtatcgacctgggaactacctactct
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgaccagggcaaccgc
atcacgccgtcgtacgtggccttcacccctgaaggggagcgactgatcggcgatgcagcc
aagaaccagctcacctccaaccctgagaacactgtcttcgacgccaagcgtctcatcggc
cgcacttggaatgacccatctgtgcagcaggacatcaagttcttgcctttcaaggttgtt
gaaaagaaaactaaaccatatatccaagtcgatattggaggtgggcagacaaagacgttt
gctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaagttacccatgcagtagttactgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgttatgaggataatcaat
gagcctacagcagctgctattgcttatggcctggacaagagggaaggggagaagaacatc
ctggtgtttgatctgggtggtggaaccttcgatgtgtctcttctaaccattgataacggt
gtctttgaagttgtggccactaatggagatactcatctgggtggagaagactttgaccag
cgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagcagtgcagaaactccgacgtgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgagattgagtctttctatgaaggagaagacttctctgag
accctgactcgggccaagtttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaagtgctggaagattctgatttaaagaagtctgatattgatgaaattgtt
cttgtcggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaggctgtagcatatggtgctgctgtt
caggctggtgttctctctggtgatcaagatacaggtgatctggtactgctggatgtatgt
ccccttacactcggtattgagactgtgggaggcgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcttctgataatcaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctcacgaaagacaatcaccttctggga
acttttgatctgacgggaattcctcctgctcctcgtggggttccacagattgaagtcacc
tttgagatagatgtgaatggcattcttcgcgtgacggctgaagacaaaggtacaggcaac
aaaaataagatcaccattaccaatgaccaaaatcgcctaacacctgaagaaattgaaagg
atggttaatgatgccgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
accagaaatgaattggaaagctatgcctattctctaaagaatcagattggggataaagaa
aagctgggaggcaaactttcttctgaagataaggagaccatggaaaaagccgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgtccagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaagcagcagacaaagatgagttgtag
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