Manis javanica (Malayan pangolin): 108400537
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Entry
108400537 CDS
T06054
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04020
Calcium signaling pathway
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04148
Efferocytosis
mjv04260
Cardiac muscle contraction
mjv04261
Adrenergic signaling in cardiomyocytes
mjv04380
Osteoclast differentiation
mjv04919
Thyroid hormone signaling pathway
mjv04972
Pancreatic secretion
mjv05010
Alzheimer disease
mjv05017
Spinocerebellar ataxia
mjv05022
Pathways of neurodegeneration - multiple diseases
mjv05410
Hypertrophic cardiomyopathy
mjv05412
Arrhythmogenic right ventricular cardiomyopathy
mjv05414
Dilated cardiomyopathy
mjv05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
108400537 (ATP2A2)
04024 cAMP signaling pathway
108400537 (ATP2A2)
04022 cGMP-PKG signaling pathway
108400537 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
108400537 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108400537 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
108400537 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
108400537 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
108400537 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
108400537 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
108400537 (ATP2A2)
05017 Spinocerebellar ataxia
108400537 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
108400537 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
108400537 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
108400537 (ATP2A2)
05414 Dilated cardiomyopathy
108400537 (ATP2A2)
05415 Diabetic cardiomyopathy
108400537 (ATP2A2)
Enzymes [BR:
mjv01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
108400537 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
108400537
NCBI-ProteinID:
XP_036870141
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKIEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGSTKIPMTPGV
KQKVMSVIREWGSGSDTLRCLGLATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRTEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFRQDEDVAAKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSYYQLSHFLQCKEDNPDFVGVDCAVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagtttggagcaggtcaagaagctgaaggagagatggggctccaacgag
ttaccggctgaagaagggaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtgtggcaggaaagaaatgctgaaaatgcaattgaagcccttaag
gagtatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtacagcgaatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgacataaggctaacttccatcaagtctactactctcagagtggaccagtccattctc
acaggtgagtctgtctctgtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgctcttttctggtaccaacattgctgctggtaaagccatg
ggagttgtggtggcaactggagtgaacactgaaattggcaagatccgggatgaaatggtg
gcaacagaacaggagagaacacccctccagcagaaactagatgaatttggggaacagctt
tccaaagtcatctcccttatttgcattgccgtctggatcataaatattgggcatttcaat
gacccagttcatggaggctcctggatcagaggtgctatttactactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggtctacctgctgtcatcaccacctgcctggcc
ctgggaacacgcagaatggcaaagaaaaatgccattgttcgaagccttccttccgtagaa
acccttggttgtacttctgttatctgctcagacaaaactggtacacttacgacaaaccag
atgtcagtctgcaggatgttcattctggacaaaattgaaggtgatacttgttcccttaat
gagtttaccataactggatcaacatatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcagtatgacggtcttgtagaattggcaacaatttgtgctctttgt
aatgactctgctttagattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaacgagcaaatgcctgcaactcggtcattaaacagttgatgaaa
aaagaatttactctagagttttcacgtgacagaaaatcaatgtcggtttattgtacacca
aacaaaccaagccggacatcaatgagcaaaatgtttgtgaagggggctcctgaaggtgtc
attgacaggtgcacccatgtccgagttggaagtactaaaatccctatgacccctggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagtggcagcgataccctgagatgc
ctgggtctggccactcatgacaatccactgagaagagaagaaatgaacctcgaggactct
gccaactttattaaatacgagaccaatctgacttttgtgggctgcgtgggcatgttggat
cctccaagaactgaagtggcctcttctgtgaagctttgccgacaagcaggcatccgggtc
atcatgatcacaggggacaacaaaggcaccgctgtggccatctgtcgccgaattggcatc
ttcaggcaggacgaggatgtggcagcaaaggcttttacaggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgcctgaatgcccgctgttttgctcgagttgaacct
tcccataaatctaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggatggtgtgaatgatgctcctgccctgaagaaatctgagattggcattgccatgggc
tctggcaccgcagtggctaaaactgcctccgagatggtcctggcagacgacaacttctcc
accattgtggccgccgtcgaggaggggcgggcaatatacaacaatatgaagcagttcatc
cgctacctcatctcatcaaacgtgggggaagttgtctgtattttcctgacagcagctctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaacctggtgacagacggc
ctgcctgctactgccctggggttcaaccctcctgacctggacatcatgaataaaccaccc
cggaacccaaaggaaccactaatcagtgggtggctctttttccgttacctggctattggc
tgttacgttggtgctgctactgtgggtgctgctgcgtggtggttcattgctgcagacggc
ggtccaagagtgtcctactaccagctgagtcatttcctacagtgtaaagaggacaatcca
gacttcgtaggagtggattgtgcagtctttgaatccccatacccgatgacaatggcgctc
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccttgggagaatatctggctcgtgggctccatctgcctgtccatg
tcgctgcacttcctaatcctctatgtggaacctttgccacttattttccagatcacaccg
ctgaatttgacccagtggctaatggtgctgaaaatctccctgcctgtgattctaatggac
gagacactcaagtttgtggcccgcaactacctggaacctgcaatactggagtaa
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