Manis javanica (Malayan pangolin): 108402090
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Entry
108402090 CDS
T06054
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00230
Purine metabolism
mjv01100
Metabolic pathways
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04924
Renin secretion
mjv05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
108402090 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
108402090 (PDE3A)
04022 cGMP-PKG signaling pathway
108402090 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
108402090 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
108402090 (PDE3A)
Enzymes [BR:
mjv01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
108402090 (PDE3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
108402090
NCBI-ProteinID:
XP_036876247
LinkDB
All DBs
Position
Unknown
AA seq
1130 aa
AA seq
DB search
MAAPGEAARVGDQPGAGGVSPAPAAAGRRRRRWGDLALQPPRRSRKLSPALCAGSLPLLL
ALLVRLVRGETGCDPVQSKEAVAVAAAEAAAAPGAEGGVLPGPRGGAPGGGAPPSPWLQP
SALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCVGEALVQIGLGVGEDHLLSLPAAG
VVLSCLAAATWLVLKLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAYLAGVLGILLA
RYVEQILPQSAGAAPREHFGSQLIAGTKEDIPVFKRRRRSSSVVSAEMSGCSSKSHRRTS
LPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCT
SLRAVSNLLSTQLTFQAIHKPRVNPVVSFSENYTCSDSEENSEKDKLAIPKRLRRSLPPG
LLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSAVSSDSWNNPVMTTLTK
SRSFTSSYAVSAANHIKAKKPNRPGALAKISPLSSPCSSPLQGTPTSSPISKVSAVQFPE
SSDATAKQRLSSHRALTYTQSAPDLSPQILAPPVICSSCGRPYSQGSPADGSLERSGAAI
QTPGRPDDTAQVTSDYETNNNSDSSDIVQNEDETECVREPPRKTSACSTYTSETMIFLDK
PMLAPEPLVMDNLDPIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAFK
IPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSASDSD
SDSGFAHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLV
ATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATD
LKKHFDFVTKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKSKELHLQWTEGIV
NEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCSSYDSAGLMPGKWVED
SDESGDTDDPEEEEEEAPNEEEICESDESPRKKTFKRRKVYCQITQHLLQNHKMWKKAIE
EEQRLAGVEDQSLDQTPQQHPPEQIQAIREEEEEKGKPSGEGIPAPEPNQ
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcagcgcccggcgaggccgcccgggtcggggaccagcccggcgccgggggcgtgagt
ccggcccccgcggccgcgggccgccgccgccgccgctggggcgacctggcgctgcagccg
ccccggcgctcgcggaaactttccccggcgctgtgcgcgggctccctgcctctcctgctg
gcgctgctggtgaggctggtccgcggggagaccggctgtgacccggtgcagagcaaggag
gcggtggcggtggcggcggcggaggcggcagcggccccgggagcagaagggggcgttctc
ccggggcctcggggaggtgctcccgggggcggtgcgccgcccagcccctggctgcagccc
tcggcgttgctcttcagtctcctgtgtgccttcttctggatgggcttgtacctcctgcgc
gccggggtgcgcctgcctctggcggtcgcgctgctggccgcctgctgcgtgggggaagcg
ctcgtgcagattgggttgggcgtcggggaggatcacttactctcgctcccggccgcgggg
gtggtgctcagctgcctggccgccgcgacatggctggtgctgaagctgaggctgggcgtc
ctcatgatcgccttgactagcgcggtcaggaccgtgtccctcatttccttagagaggttc
aaggtcgcctggagaccttacctggcgtacttggctggcgtgctggggatcctcctggcg
aggtacgtggagcaaatcttgccgcagtccgcgggggcggctccgagggagcattttggg
tcccagctaattgctgggaccaaggaagacatcccggtatttaagaggaggaggcggtcc
agctccgtggtgtccgccgagatgtccggctgcagcagcaagtcccatcggaggacctcc
ctgccctgcatacccagggaacagcttatggggcattcagaatgggaccacaaacgaggg
ccacgagggtcacagtcttcaggaaccagtatcactgtggatattgccgtgatgggtgag
gctcacggcctcattactgacctcctggcagacccctctctgccccccaatgtgtgcacg
tctttgagggcagtaagcaacctgctcagcacccagctcaccttccaggccattcacaag
cccagagtgaatcctgtcgtttccttcagtgaaaactatacctgttctgattctgaagaa
aactccgaaaaagacaagctggctattcccaagcgcctgagaaggagtttgcccccgggt
ttgttgagacgagtttcatcaacatggacaaccaccacgtcggccactggccttcccact
ctggagcccgccccagtacggagggaccgtagtgccagcatcaaactgcatgaagcacct
tcatccagtgctgttagttctgattcttggaataacccagtgatgacgaccctcaccaaa
agcagatccttcacttcgtcctatgctgtgtccgcagctaaccacataaaggctaaaaag
ccaaatcgaccaggtgccctggctaaaatctcacctctgtcctcaccctgctcctcacct
ctccaagggactcctaccagcagccccatcagcaaagtttctgcagtccagtttccagaa
tcttcagacgcaactgccaaacaacgcctaagttctcacagggccttaacttatactcaa
agtgcccctgacctctctcctcagatcctcgctccacctgttatatgtagcagctgtggc
agaccatattcccaaggcagtcctgctgatgggtccctggaaagaagtggtgcagccatt
cagaccccaggcagaccagatgacactgctcaggttacctctgattatgaaaccaataac
aacagtgacagcagtgacattgtacagaatgaagatgagactgagtgtgtgagggagcct
cccaggaaaacgtcggcttgcagcacctacacgtctgagaccatgatattcctggacaaa
ccaatgcttgctcctgaacctctcgtcatggacaacttggacccaattatggagcagcta
aatacttggaatttcccaatttttgatttagtggaaaaaataggaaggaaatgtggccgt
attcttagtcaggtatcatacagactttttgaagacatgggcctctttgaggcttttaaa
attccagtcagggaatttatgaattattttcatgctctggagattggatacagggaaatt
ccttatcataacagaatccatgccactgacgtcttacatgctgtttggtatcttaccacg
cagcccattccaggcctctcaactgtgattaatgatcacggatcagcaagtgattcagat
tctgacagtggatttgcacatggacatatgggatatgtattctcaaaaatgtataatgtg
ccagatgataaatacggatgcctgtctggcaatattcctgccctggagttgatggcactg
tatgtagcggctgccatgcatgattatgaccaccccggaaggactaatgctttcctcgtt
gctactagtgcccctcaggcggtgctgtacaacgatcgctcagttttggagaatcatcat
gcagctgctgcatggaatcttttcatgtcccggccagagtataacttcttagttaacctt
gaccatgtggaatttaagcatttccgtttccttgtcattgaagccattttggccactgac
ctgaagaaacactttgacttcgtaaccaaatttaatgccaaggtgaatgatgatgttgga
atagattggaccaatgaaaatgatcgtctactggtttgtcaaatgtgtataaagttggct
gatatcaatgggccagctaaaagtaaagagctccatcttcagtggacagagggtattgtc
aatgaattttatgaacagggtgacgaagaggccagccttggattaccaataagccctttc
atggaccgttccgctcctcagttggccaatcttcaggaatcctttatctctcatattgtg
ggtcctctgtgcagctcctatgactcagcaggactgatgccagggaaatgggtggaagac
agtgatgagtcaggagatacggatgacccagaagaggaagaggaggaagccccaaatgaa
gaggaaatctgtgaaagtgatgaatctccaagaaagaaaactttcaaaaggaggaaagtc
tactgccaaataactcagcacctcctgcagaaccacaagatgtggaagaaagccattgag
gaggaacagcggttggcaggcgtagaagatcagtccctagaccagaccccccagcagcat
cccccagagcagatccaggccatccgggaagaagaggaagagaaagggaagccgagcgga
gaggggatcccagctcctgagccgaatcagtga
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