| Entry |
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| Symbol |
HIF1A
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| Name |
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
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| KO |
| K08268 | hypoxia-inducible factor 1 alpha |
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| Organism |
mjv Manis javanica (Malayan pangolin)
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| Pathway |
| mjv04919 | Thyroid hormone signaling pathway |
| mjv05167 | Kaposi sarcoma-associated herpesvirus infection |
| mjv05208 | Chemical carcinogenesis - reactive oxygen species |
| mjv05230 | Central carbon metabolism in cancer |
| mjv05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mjv00001]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
108404522 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108404522 (HIF1A)
04137 Mitophagy - animal
108404522 (HIF1A)
04148 Efferocytosis
108404522 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
108404522 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108404522 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108404522 (HIF1A)
05205 Proteoglycans in cancer
108404522 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
108404522 (HIF1A)
05230 Central carbon metabolism in cancer
108404522 (HIF1A)
05231 Choline metabolism in cancer
108404522 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108404522 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
108404522 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
108404522 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:mjv03000]
108404522 (HIF1A)
Transcription factors [BR:mjv03000]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
108404522 (HIF1A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
821 aa
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNNNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPDELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGGSDTET
DDQQLEEVPLYNDVMLPSSTEKLRSMNLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQNQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPQSASTITVFQ
PTPMQEPITATPIATTDELKTVTKDGMEDIKILIASPSPTHVPKETTSATTSLYSDTGSR
TASPSRAGKGVIEQTEKPHPRSPNLLSVTLSQRSTIPEEELNPKILALQNAQRKRKIEHD
GSLFQAVGIGTLLQPPDDHATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQ
SMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN |
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| NT seq |
2466 nt +upstreamnt +downstreamnt
atggagggcgccggcggcgcgaacgacaaaaaaaagataagttctgaacgtcgaaaagaa
aagtctagagatgcagcgaggtctcggcgaagtaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccataatgtgagctcgcatcttgataaggcttctgttatg
aggcttaccatcagttatttgcgtgtgaggaaacttctggatgctggtgacttggatatt
gaagatgaaatgaaggcacagatgaactgcttctacttgaaagccttggatggttttgtt
atggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatacatg
gggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacgcacagaaatggccttgtgaaaaagggtaaagag
caaaatacacagcgaagctttttcctcagaatgaagtgtaccctaactagccgagggaga
actatgaacataaagtctgcaacatggaaagtacttcactgcacaggccatattcatgta
tatgataccaacaataaccaatctcagtgtgggtataagaaaccacctatgacatgcttg
gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag
acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatgggctatgagccagatgaacttttgggccgctcaatttatgaatattatcat
gctttggactctgatcatctgaccaaaactcatcatgatatgtttactaaaggacaggtc
accacaggacagtacaggatgcttgccaaaagaggaggatatgtctgggttgaaactcaa
gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat
gttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca
gaagatacaagtagtctttttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagattttggcggcagtgacacagaaact
gatgatcaacaacttgaggaagttccgctgtataatgatgtgatgctcccctcatccacc
gaaaaactgcgaagtatgaatttggcaatgtctccattacctgcttctgaaactccaaaa
ccacttcgaagtagtgctgatcctgcactcaatcaggaagttgcattaaaattagaacca
aatccagagtcattggaactttcttttaccatgccccagattcaaaatcagccagctagt
ccttctgatggaagcactagacaaagttcaccggagcccaacagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaacttttt
gctgaagacacggaagcaaagaatccattttccactcaggacactgatttagacttggag
atgttagctccttatatcccaatggatgacgacttccagttacgttccttcgatcagttg
tcaccattggaaagcagttctgcaagccctcaaagtgcgagcacaattacagtattccag
ccgactccaatgcaggaacctattaccgccactcccattgccaccactgatgaattaaaa
acagtgacgaaagatggtatggaagacattaaaatattgattgcatctccatctcctact
catgtacctaaagaaactactagtgccacaacatcactatatagtgatactggaagtcgg
acagcttcaccaagtagagcaggaaaaggagtcatagaacagacagaaaaacctcatcca
aggagccctaacctgttatctgtcactttgagtcaaagatctaccattcctgaggaagaa
ctaaatccaaagatactagctttgcagaatgctcaaagaaagcgaaaaatagaacatgat
ggttccctttttcaagcagtaggaattggaacattattacagccgcctgatgatcatgca
actactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgaacagaatgga
atggagcaaaagacaattattttaataccctctgatttagcatgtagactgttggggcaa
tcaatggatgagagtggattaccacagctgaccagttatgattgtgaagttaatgctcct
gtacaaggcagcagaaacctactgcagggtgaagagttactcagagctttggatcaagtt
aactga |
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