Manis javanica (Malayan pangolin): 108404522
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Entry
108404522 CDS
T06054
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04066
HIF-1 signaling pathway
mjv04137
Mitophagy - animal
mjv04140
Autophagy - animal
mjv04148
Efferocytosis
mjv04659
Th17 cell differentiation
mjv04919
Thyroid hormone signaling pathway
mjv05167
Kaposi sarcoma-associated herpesvirus infection
mjv05200
Pathways in cancer
mjv05205
Proteoglycans in cancer
mjv05208
Chemical carcinogenesis - reactive oxygen species
mjv05211
Renal cell carcinoma
mjv05230
Central carbon metabolism in cancer
mjv05231
Choline metabolism in cancer
mjv05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
108404522 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108404522 (HIF1A)
04137 Mitophagy - animal
108404522 (HIF1A)
04148 Efferocytosis
108404522 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
108404522 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
108404522 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108404522 (HIF1A)
05205 Proteoglycans in cancer
108404522 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
108404522 (HIF1A)
05230 Central carbon metabolism in cancer
108404522 (HIF1A)
05231 Choline metabolism in cancer
108404522 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108404522 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
108404522 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
108404522 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mjv03000
]
108404522 (HIF1A)
Transcription factors [BR:
mjv03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
108404522 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
108404522
NCBI-ProteinID:
XP_017527630
LinkDB
All DBs
Position
Unknown
AA seq
821 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNNNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPDELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGGSDTET
DDQQLEEVPLYNDVMLPSSTEKLRSMNLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQNQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPQSASTITVFQ
PTPMQEPITATPIATTDELKTVTKDGMEDIKILIASPSPTHVPKETTSATTSLYSDTGSR
TASPSRAGKGVIEQTEKPHPRSPNLLSVTLSQRSTIPEEELNPKILALQNAQRKRKIEHD
GSLFQAVGIGTLLQPPDDHATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQ
SMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaaaaaaaagataagttctgaacgtcgaaaagaa
aagtctagagatgcagcgaggtctcggcgaagtaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccataatgtgagctcgcatcttgataaggcttctgttatg
aggcttaccatcagttatttgcgtgtgaggaaacttctggatgctggtgacttggatatt
gaagatgaaatgaaggcacagatgaactgcttctacttgaaagccttggatggttttgtt
atggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatacatg
gggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacgcacagaaatggccttgtgaaaaagggtaaagag
caaaatacacagcgaagctttttcctcagaatgaagtgtaccctaactagccgagggaga
actatgaacataaagtctgcaacatggaaagtacttcactgcacaggccatattcatgta
tatgataccaacaataaccaatctcagtgtgggtataagaaaccacctatgacatgcttg
gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag
acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatgggctatgagccagatgaacttttgggccgctcaatttatgaatattatcat
gctttggactctgatcatctgaccaaaactcatcatgatatgtttactaaaggacaggtc
accacaggacagtacaggatgcttgccaaaagaggaggatatgtctgggttgaaactcaa
gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat
gttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca
gaagatacaagtagtctttttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagctgctggagacacaatcatatctttagattttggcggcagtgacacagaaact
gatgatcaacaacttgaggaagttccgctgtataatgatgtgatgctcccctcatccacc
gaaaaactgcgaagtatgaatttggcaatgtctccattacctgcttctgaaactccaaaa
ccacttcgaagtagtgctgatcctgcactcaatcaggaagttgcattaaaattagaacca
aatccagagtcattggaactttcttttaccatgccccagattcaaaatcagccagctagt
ccttctgatggaagcactagacaaagttcaccggagcccaacagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaattcaagttggaattggtagagaaacttttt
gctgaagacacggaagcaaagaatccattttccactcaggacactgatttagacttggag
atgttagctccttatatcccaatggatgacgacttccagttacgttccttcgatcagttg
tcaccattggaaagcagttctgcaagccctcaaagtgcgagcacaattacagtattccag
ccgactccaatgcaggaacctattaccgccactcccattgccaccactgatgaattaaaa
acagtgacgaaagatggtatggaagacattaaaatattgattgcatctccatctcctact
catgtacctaaagaaactactagtgccacaacatcactatatagtgatactggaagtcgg
acagcttcaccaagtagagcaggaaaaggagtcatagaacagacagaaaaacctcatcca
aggagccctaacctgttatctgtcactttgagtcaaagatctaccattcctgaggaagaa
ctaaatccaaagatactagctttgcagaatgctcaaagaaagcgaaaaatagaacatgat
ggttccctttttcaagcagtaggaattggaacattattacagccgcctgatgatcatgca
actactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgaacagaatgga
atggagcaaaagacaattattttaataccctctgatttagcatgtagactgttggggcaa
tcaatggatgagagtggattaccacagctgaccagttatgattgtgaagttaatgctcct
gtacaaggcagcagaaacctactgcagggtgaagagttactcagagctttggatcaagtt
aactga
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integrated database retrieval system
