KEGG   Manis javanica (Malayan pangolin): 108405137
Entry
108405137         CDS       T06054                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04010  MAPK signaling pathway
mjv04015  Rap1 signaling pathway
mjv04218  Cellular senescence
mjv04380  Osteoclast differentiation
mjv04620  Toll-like receptor signaling pathway
mjv04664  Fc epsilon RI signaling pathway
mjv04668  TNF signaling pathway
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04912  GnRH signaling pathway
mjv04935  Growth hormone synthesis, secretion and action
mjv04936  Alcoholic liver disease
mjv05014  Amyotrophic lateral sclerosis
mjv05022  Pathways of neurodegeneration - multiple diseases
mjv05132  Salmonella infection
mjv05135  Yersinia infection
mjv05145  Toxoplasmosis
mjv05161  Hepatitis B
mjv05163  Human cytomegalovirus infection
mjv05167  Kaposi sarcoma-associated herpesvirus infection
mjv05169  Epstein-Barr virus infection
mjv05170  Human immunodeficiency virus 1 infection
mjv05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05417  Lipid and atherosclerosis
mjv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108405137 (MAP2K6)
   04015 Rap1 signaling pathway
    108405137 (MAP2K6)
   04668 TNF signaling pathway
    108405137 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    108405137 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    108405137 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    108405137 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108405137 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    108405137 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108405137 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108405137 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108405137 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108405137 (MAP2K6)
   05161 Hepatitis B
    108405137 (MAP2K6)
   05163 Human cytomegalovirus infection
    108405137 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108405137 (MAP2K6)
   05169 Epstein-Barr virus infection
    108405137 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108405137 (MAP2K6)
   05135 Yersinia infection
    108405137 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108405137 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108405137 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    108405137 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108405137 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    108405137 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108405137 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108405137 (MAP2K6)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     108405137 (MAP2K6)
Protein kinases [BR:mjv01001]
 Serine/threonine kinases: STE group
  STE7 family
   108405137 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 108405137
NCBI-ProteinID: XP_036853278
LinkDB
Position
Unknown
AA seq 335 aa
MRAPCPGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMEL
GRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGAL
FREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRD
VKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSD
IWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNS
KERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1008 nt   +upstreamnt  +downstreamnt
atgagagctccatgcccaggcaagaagcgaaaccctggcctgaaaattccgaaagaagct
tttgaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatt
tctattggaaaccagaactttgaggtgaaggcggatgacctggagcctataatggaactg
ggccgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatg
gcagtgaagcggatccgagccacagtaaatagccaggagcagaaaaggctactgatggat
ttggatatttccatgaggacagtggactgtcctttcacggtgaccttttacggcgctctc
ttccgggagggtgatgtttggatctgcatggagctcatggatacgtcactagataaattc
tacaaacaagtcattgataaaggccaaacaataccagaggacatcttagggaaaatagca
gtttctattgtaaaagcgttagaacatttacacagtaagctctctgtcattcatcgagac
gtcaagccttccaacgtgctgatcaatactctgggccaagtcaagatgtgtgattttgga
atcagtggctaccttgtagactctgtcgctaaaaccattgacgcgggatgcaaaccgtac
atggctcctgaaagaataaacccagagctcaaccagaaggggtacagtgtgaagtctgac
atttggagtctgggcatcacaatgattgaattggccatccttcggtttccctacgattcg
tggggaactcctttccagcagctcaaacaggtggtagaggagccatcgccgcaactccct
gcagacaagttctccgaagagtttgttgactttacctcccagtgcttgaagaagaattcc
aaagaacggccgacatacccagagctcatgcaacatccatttttcaccctgcacgaatcc
aaagcaacagacgtggcatcttttgtaaaactgattcttggagattga

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