KEGG   Manis javanica (Malayan pangolin): 108408343
Entry
108408343         CDS       T06054                                 
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv01522  Endocrine resistance
mjv04010  MAPK signaling pathway
mjv04014  Ras signaling pathway
mjv04020  Calcium signaling pathway
mjv04024  cAMP signaling pathway
mjv04062  Chemokine signaling pathway
mjv04081  Hormone signaling
mjv04082  Neuroactive ligand signaling
mjv04114  Oocyte meiosis
mjv04140  Autophagy - animal
mjv04211  Longevity regulating pathway
mjv04213  Longevity regulating pathway - multiple species
mjv04261  Adrenergic signaling in cardiomyocytes
mjv04270  Vascular smooth muscle contraction
mjv04310  Wnt signaling pathway
mjv04340  Hedgehog signaling pathway
mjv04371  Apelin signaling pathway
mjv04530  Tight junction
mjv04540  Gap junction
mjv04611  Platelet activation
mjv04713  Circadian entrainment
mjv04714  Thermogenesis
mjv04720  Long-term potentiation
mjv04723  Retrograde endocannabinoid signaling
mjv04724  Glutamatergic synapse
mjv04725  Cholinergic synapse
mjv04726  Serotonergic synapse
mjv04727  GABAergic synapse
mjv04728  Dopaminergic synapse
mjv04740  Olfactory transduction
mjv04742  Taste transduction
mjv04750  Inflammatory mediator regulation of TRP channels
mjv04910  Insulin signaling pathway
mjv04911  Insulin secretion
mjv04912  GnRH signaling pathway
mjv04913  Ovarian steroidogenesis
mjv04914  Progesterone-mediated oocyte maturation
mjv04915  Estrogen signaling pathway
mjv04916  Melanogenesis
mjv04918  Thyroid hormone synthesis
mjv04919  Thyroid hormone signaling pathway
mjv04921  Oxytocin signaling pathway
mjv04922  Glucagon signaling pathway
mjv04923  Regulation of lipolysis in adipocytes
mjv04924  Renin secretion
mjv04925  Aldosterone synthesis and secretion
mjv04926  Relaxin signaling pathway
mjv04927  Cortisol synthesis and secretion
mjv04928  Parathyroid hormone synthesis, secretion and action
mjv04934  Cushing syndrome
mjv04935  Growth hormone synthesis, secretion and action
mjv04961  Endocrine and other factor-regulated calcium reabsorption
mjv04962  Vasopressin-regulated water reabsorption
mjv04970  Salivary secretion
mjv04971  Gastric acid secretion
mjv04976  Bile secretion
mjv05012  Parkinson disease
mjv05020  Prion disease
mjv05030  Cocaine addiction
mjv05031  Amphetamine addiction
mjv05032  Morphine addiction
mjv05034  Alcoholism
mjv05146  Amoebiasis
mjv05163  Human cytomegalovirus infection
mjv05165  Human papillomavirus infection
mjv05166  Human T-cell leukemia virus 1 infection
mjv05200  Pathways in cancer
mjv05203  Viral carcinogenesis
mjv05205  Proteoglycans in cancer
mjv05207  Chemical carcinogenesis - receptor activation
mjv05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108408343 (PRKACB)
   04014 Ras signaling pathway
    108408343 (PRKACB)
   04310 Wnt signaling pathway
    108408343 (PRKACB)
   04340 Hedgehog signaling pathway
    108408343 (PRKACB)
   04371 Apelin signaling pathway
    108408343 (PRKACB)
   04020 Calcium signaling pathway
    108408343 (PRKACB)
   04024 cAMP signaling pathway
    108408343 (PRKACB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    108408343 (PRKACB)
   04081 Hormone signaling
    108408343 (PRKACB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    108408343 (PRKACB)
  09143 Cell growth and death
   04114 Oocyte meiosis
    108408343 (PRKACB)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    108408343 (PRKACB)
   04540 Gap junction
    108408343 (PRKACB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108408343 (PRKACB)
   04062 Chemokine signaling pathway
    108408343 (PRKACB)
  09152 Endocrine system
   04911 Insulin secretion
    108408343 (PRKACB)
   04910 Insulin signaling pathway
    108408343 (PRKACB)
   04922 Glucagon signaling pathway
    108408343 (PRKACB)
   04923 Regulation of lipolysis in adipocytes
    108408343 (PRKACB)
   04912 GnRH signaling pathway
    108408343 (PRKACB)
   04913 Ovarian steroidogenesis
    108408343 (PRKACB)
   04915 Estrogen signaling pathway
    108408343 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    108408343 (PRKACB)
   04921 Oxytocin signaling pathway
    108408343 (PRKACB)
   04926 Relaxin signaling pathway
    108408343 (PRKACB)
   04935 Growth hormone synthesis, secretion and action
    108408343 (PRKACB)
   04918 Thyroid hormone synthesis
    108408343 (PRKACB)
   04919 Thyroid hormone signaling pathway
    108408343 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    108408343 (PRKACB)
   04916 Melanogenesis
    108408343 (PRKACB)
   04924 Renin secretion
    108408343 (PRKACB)
   04925 Aldosterone synthesis and secretion
    108408343 (PRKACB)
   04927 Cortisol synthesis and secretion
    108408343 (PRKACB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108408343 (PRKACB)
   04270 Vascular smooth muscle contraction
    108408343 (PRKACB)
  09154 Digestive system
   04970 Salivary secretion
    108408343 (PRKACB)
   04971 Gastric acid secretion
    108408343 (PRKACB)
   04976 Bile secretion
    108408343 (PRKACB)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    108408343 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    108408343 (PRKACB)
  09156 Nervous system
   04724 Glutamatergic synapse
    108408343 (PRKACB)
   04727 GABAergic synapse
    108408343 (PRKACB)
   04725 Cholinergic synapse
    108408343 (PRKACB)
   04728 Dopaminergic synapse
    108408343 (PRKACB)
   04726 Serotonergic synapse
    108408343 (PRKACB)
   04720 Long-term potentiation
    108408343 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    108408343 (PRKACB)
  09157 Sensory system
   04740 Olfactory transduction
    108408343 (PRKACB)
   04742 Taste transduction
    108408343 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    108408343 (PRKACB)
  09149 Aging
   04211 Longevity regulating pathway
    108408343 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    108408343 (PRKACB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    108408343 (PRKACB)
   04714 Thermogenesis
    108408343 (PRKACB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108408343 (PRKACB)
   05205 Proteoglycans in cancer
    108408343 (PRKACB)
   05207 Chemical carcinogenesis - receptor activation
    108408343 (PRKACB)
   05203 Viral carcinogenesis
    108408343 (PRKACB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108408343 (PRKACB)
   05163 Human cytomegalovirus infection
    108408343 (PRKACB)
   05165 Human papillomavirus infection
    108408343 (PRKACB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    108408343 (PRKACB)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    108408343 (PRKACB)
   05020 Prion disease
    108408343 (PRKACB)
  09165 Substance dependence
   05030 Cocaine addiction
    108408343 (PRKACB)
   05031 Amphetamine addiction
    108408343 (PRKACB)
   05032 Morphine addiction
    108408343 (PRKACB)
   05034 Alcoholism
    108408343 (PRKACB)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    108408343 (PRKACB)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108408343 (PRKACB)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108408343 (PRKACB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mjv01001]
    108408343 (PRKACB)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mjv03019]
    108408343 (PRKACB)
   03036 Chromosome and associated proteins [BR:mjv03036]
    108408343 (PRKACB)
Enzymes [BR:mjv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     108408343 (PRKACB)
Protein kinases [BR:mjv01001]
 Serine/threonine kinases: AGC group
  PKA family
   108408343 (PRKACB)
Messenger RNA biogenesis [BR:mjv03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     108408343 (PRKACB)
Chromosome and associated proteins [BR:mjv03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    108408343 (PRKACB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 108408343
NCBI-ProteinID: XP_017533791
LinkDB
Position
Unknown
AA seq 397 aa
MAAYREQPCNQYTGTTALQKLEGFASRLFHRHSKVPAHDQKTALENDSLHFSEHTALWNR
SMKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKI
LDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLR
RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG
RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG
KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAP
FIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFCEF
NT seq 1194 nt   +upstreamnt  +downstreamnt
atggcagcttatagagaacaaccctgtaaccagtatacaggtacaactgctctacagaag
ttggaaggttttgctagccgattatttcatagacactctaaagttcctgcacatgatcag
aaaacagctctggaaaatgacagccttcatttctctgaacatactgccttatggaacaga
tcaatgaaagagtttctagccaaagctaaagaagactttttaaaaaaatgggaaaatcct
gctccgaataatgctgggctggaggattttgaaaggaaaaaaacccttggaacaggttca
tttggaagagtcatgttggtgaaacataaagctactgaacagtattatgccatgaagatc
ttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaaga
atattacaggcagtgaattttccttttcttgttcgactggagtattcttttaaggataat
tctaatttgtacatggttatggaatatgtccctgggggtgaaatgttttcacatctaaga
agaattggaagattcagtgaaccccatgcacggttctatgcagctcagatagtgctaaca
ttcgagtacctccactcattagacctcatctacagagatctaaaacctgaaaatctctta
attgaccaccaaggttatatccaggtcacagactttgggtttgccaaaagagttaaaggt
agaacttggacattatgtggcactccagaatatttggctccagaaataatcctcagcaag
ggctacaataaagcagtggattggtgggcattaggagtgttgatctatgaaatggctgct
ggctaccctccattctttgcagaccaaccaattcagatttatgaaaagattgtttctgga
aaggtccgattcccatcacacttcagttcagatctcaaggaccttctgagaaacctgctg
caggtggatttgacaaagaggtttggaaatctaaagaatggtgtgagtgacataaaaact
cacaagtggtttgccacaactgattggattgcaatttaccagaggaaggttgaagctcca
ttcataccaaagttcagaggctctggagataccagcaactttgatgactatgaagaagaa
gatatccgtgtctctataacagaaaaatgtgcaaaagaattttgtgaattttaa

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