Manis javanica (Malayan pangolin): 108408627 Help Entry 108408627         CDS       T06054                                  Symbol HRAS Name (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv01521   EGFR tyrosine kinase inhibitor resistance mjv01522   Endocrine resistance mjv04010   MAPK signaling pathway mjv04012   ErbB signaling pathway mjv04014   Ras signaling pathway mjv04015   Rap1 signaling pathway mjv04062   Chemokine signaling pathway mjv04068   FoxO signaling pathway mjv04071   Sphingolipid signaling pathway mjv04072   Phospholipase D signaling pathway mjv04137   Mitophagy - animal mjv04140   Autophagy - animal mjv04144   Endocytosis mjv04150   mTOR signaling pathway mjv04151   PI3K-Akt signaling pathway mjv04210   Apoptosis mjv04211   Longevity regulating pathway mjv04213   Longevity regulating pathway - multiple species mjv04218   Cellular senescence mjv04360   Axon guidance mjv04370   VEGF signaling pathway mjv04371   Apelin signaling pathway mjv04510   Focal adhesion mjv04540   Gap junction mjv04550   Signaling pathways regulating pluripotency of stem cells mjv04625   C-type lectin receptor signaling pathway mjv04630   JAK-STAT signaling pathway mjv04650   Natural killer cell mediated cytotoxicity mjv04660   T cell receptor signaling pathway mjv04662   B cell receptor signaling pathway mjv04664   Fc epsilon RI signaling pathway mjv04714   Thermogenesis mjv04720   Long-term potentiation mjv04722   Neurotrophin signaling pathway mjv04725   Cholinergic synapse mjv04726   Serotonergic synapse mjv04730   Long-term depression mjv04810   Regulation of actin cytoskeleton mjv04910   Insulin signaling pathway mjv04912   GnRH signaling pathway mjv04915   Estrogen signaling pathway mjv04916   Melanogenesis mjv04917   Prolactin signaling pathway mjv04919   Thyroid hormone signaling pathway mjv04921   Oxytocin signaling pathway mjv04926   Relaxin signaling pathway mjv04929   GnRH secretion mjv04933   AGE-RAGE signaling pathway in diabetic complications mjv04935   Growth hormone synthesis, secretion and action mjv05010   Alzheimer disease mjv05022   Pathways of neurodegeneration - multiple diseases mjv05034   Alcoholism mjv05132   Salmonella infection mjv05160   Hepatitis C mjv05161   Hepatitis B mjv05163   Human cytomegalovirus infection mjv05165   Human papillomavirus infection mjv05166   Human T-cell leukemia virus 1 infection mjv05167   Kaposi sarcoma-associated herpesvirus infection mjv05170   Human immunodeficiency virus 1 infection mjv05200   Pathways in cancer mjv05203   Viral carcinogenesis mjv05205   Proteoglycans in cancer mjv05206   MicroRNAs in cancer mjv05207   Chemical carcinogenesis - receptor activation mjv05208   Chemical carcinogenesis - reactive oxygen species mjv05210   Colorectal cancer mjv05211   Renal cell carcinoma mjv05213   Endometrial cancer mjv05214   Glioma mjv05215   Prostate cancer mjv05216   Thyroid cancer mjv05218   Melanoma mjv05219   Bladder cancer mjv05220   Chronic myeloid leukemia mjv05221   Acute myeloid leukemia mjv05223   Non-small cell lung cancer mjv05224   Breast cancer mjv05225   Hepatocellular carcinoma mjv05226   Gastric cancer mjv05230   Central carbon metabolism in cancer mjv05231   Choline metabolism in cancer mjv05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mjv05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mjv00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     108408627 (HRAS)    04015 Rap1 signaling pathway     108408627 (HRAS)    04630 JAK-STAT signaling pathway     108408627 (HRAS)    04068 FoxO signaling pathway     108408627 (HRAS)    04072 Phospholipase D signaling pathway     108408627 (HRAS)    04071 Sphingolipid signaling pathway     108408627 (HRAS)    04151 PI3K-Akt signaling pathway     108408627 (HRAS)    04150 mTOR signaling pathway     108408627 (HRAS)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     108408627 (HRAS)    04140 Autophagy - animal     108408627 (HRAS)    04137 Mitophagy - animal     108408627 (HRAS)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     108408627 (HRAS)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     108408627 (HRAS)    04660 T cell receptor signaling pathway     108408627 (HRAS)    04662 B cell receptor signaling pathway     108408627 (HRAS)    04664 Fc epsilon RI signaling pathway     108408627 (HRAS)    04062 Chemokine signaling pathway     108408627 (HRAS)   09152 Endocrine system    04929 GnRH secretion     108408627 (HRAS)    04915 Estrogen signaling pathway     108408627 (HRAS)    04917 Prolactin signaling pathway     108408627 (HRAS)    04921 Oxytocin signaling pathway     108408627 (HRAS)    04926 Relaxin signaling pathway     108408627 (HRAS)    04935 Growth hormone synthesis, secretion and action     108408627 (HRAS)    04919 Thyroid hormone signaling pathway     108408627 (HRAS)   09156 Nervous system    04725 Cholinergic synapse     108408627 (HRAS)    04726 Serotonergic synapse     108408627 (HRAS)    04720 Long-term potentiation     108408627 (HRAS)    04730 Long-term depression     108408627 (HRAS)    04722 Neurotrophin signaling pathway     108408627 (HRAS)   09158 Development and regeneration    04360 Axon guidance     108408627 (HRAS)   09149 Aging    04211 Longevity regulating pathway     108408627 (HRAS)    04213 Longevity regulating pathway - multiple species     108408627 (HRAS)   09159 Environmental adaptation    04714 Thermogenesis     108408627 (HRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108408627 (HRAS)    05206 MicroRNAs in cancer     108408627 (HRAS)    05205 Proteoglycans in cancer     108408627 (HRAS)    05207 Chemical carcinogenesis - receptor activation     108408627 (HRAS)    05208 Chemical carcinogenesis - reactive oxygen species     108408627 (HRAS)    05203 Viral carcinogenesis     108408627 (HRAS)    05230 Central carbon metabolism in cancer     108408627 (HRAS)    05231 Choline metabolism in cancer     108408627 (HRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     108408627 (HRAS)   09162 Cancer: specific types    05210 Colorectal cancer     108408627 (HRAS)    05225 Hepatocellular carcinoma     108408627 (HRAS)    05226 Gastric cancer     108408627 (HRAS)    05214 Glioma     108408627 (HRAS)    05216 Thyroid cancer     108408627 (HRAS)    05221 Acute myeloid leukemia     108408627 (HRAS)    05220 Chronic myeloid leukemia     108408627 (HRAS)    05218 Melanoma     108408627 (HRAS)    05211 Renal cell carcinoma     108408627 (HRAS)    05219 Bladder cancer     108408627 (HRAS)    05215 Prostate cancer     108408627 (HRAS)    05213 Endometrial cancer     108408627 (HRAS)    05224 Breast cancer     108408627 (HRAS)    05223 Non-small cell lung cancer     108408627 (HRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     108408627 (HRAS)    05170 Human immunodeficiency virus 1 infection     108408627 (HRAS)    05161 Hepatitis B     108408627 (HRAS)    05160 Hepatitis C     108408627 (HRAS)    05163 Human cytomegalovirus infection     108408627 (HRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     108408627 (HRAS)    05165 Human papillomavirus infection     108408627 (HRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     108408627 (HRAS)    05022 Pathways of neurodegeneration - multiple diseases     108408627 (HRAS)   09165 Substance dependence    05034 Alcoholism     108408627 (HRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     108408627 (HRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     108408627 (HRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     108408627 (HRAS)    01522 Endocrine resistance     108408627 (HRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mjv04131]     108408627 (HRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mjv04147]     108408627 (HRAS)    04031 GTP-binding proteins [BR:mjv04031]     108408627 (HRAS) Membrane trafficking [BR:mjv04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     108408627 (HRAS)  Endocytosis   Macropinocytosis    Ras GTPases     108408627 (HRAS) Exosome [BR:mjv04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    108408627 (HRAS)   Exosomal proteins of colorectal cancer cells    108408627 (HRAS) GTP-binding proteins [BR:mjv04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     108408627 (HRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 G-alpha Septin Ldh_1_N AAA_16 Motif Other DBs NCBI-GeneID:  108408627 NCBI-ProteinID:  XP_036867644 LinkDB All DBs Position Unknown AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKARKLSPPDEGGPG CMSCKCLLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacggaatataagctggtggtggtgggcgctgggggcgtggggaagagtgccctgacc atccagctcatccagaaccacttcgtggacgagtatgaccccaccatcgaggattcctac cggaagcaagtggtcattgatggggagacgtgtctgctagacatcctggacacggcgggc caggaggagtacagcgccatgcgggaccagtacatgcgtactggggagggcttcctctgt gtgttcgccatcaacaacaccaaatcttttgaggacatccaccaatacagggagcagatc aagcgagtgaaggactcagacgatgtgcccatggtcctagtcgggaacaagtgtgacctg gctgcacgcactgtggagtctcggcaggcacaggaccttgcccgaagctatggcatcccc tacatagagacatcggccaagacgcgccagggcgtggaggatgccttctacaccctggtg cgtgagatccggcagcacaaggcgcgcaaactgagcccgccggacgagggtggcccaggc tgcatgagctgcaagtgcctgctctcctga

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