KEGG   Manis javanica (Malayan pangolin): 108410024
Entry
108410024         CDS       T06054                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb isoform X1
  KO
K06476  integrin alpha 2B
Organism
mjv  Manis javanica (Malayan pangolin)
Pathway
mjv04015  Rap1 signaling pathway
mjv04151  PI3K-Akt signaling pathway
mjv04510  Focal adhesion
mjv04512  ECM-receptor interaction
mjv04611  Platelet activation
mjv04613  Neutrophil extracellular trap formation
mjv04640  Hematopoietic cell lineage
mjv04810  Regulation of actin cytoskeleton
mjv04820  Cytoskeleton in muscle cells
mjv05165  Human papillomavirus infection
mjv05200  Pathways in cancer
mjv05222  Small cell lung cancer
mjv05410  Hypertrophic cardiomyopathy
mjv05412  Arrhythmogenic right ventricular cardiomyopathy
mjv05414  Dilated cardiomyopathy
mjv05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mjv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    108410024 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    108410024 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    108410024 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    108410024 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    108410024 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    108410024 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    108410024 (ITGA2B)
   04611 Platelet activation
    108410024 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    108410024 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108410024 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    108410024 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    108410024 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    108410024 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    108410024 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    108410024 (ITGA2B)
   05414 Dilated cardiomyopathy
    108410024 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mjv01009]
    108410024 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mjv04147]
    108410024 (ITGA2B)
   04515 Cell adhesion molecules [BR:mjv04515]
    108410024 (ITGA2B)
   04090 CD molecules [BR:mjv04090]
    108410024 (ITGA2B)
Protein phosphatases and associated proteins [BR:mjv01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     108410024 (ITGA2B)
Exosome [BR:mjv04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   108410024 (ITGA2B)
Cell adhesion molecules [BR:mjv04515]
 Integrins
  Integrin alpha subunits
   108410024 (ITGA2B)
CD molecules [BR:mjv04090]
 Proteins
  108410024 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha
Other DBs
NCBI-GeneID: 108410024
NCBI-ProteinID: XP_036853504
LinkDB
Position
Unknown
AA seq 1035 aa
MVRALCPFHALWLLEWVQLLLGPGAAPPTSALNLDPVQLTFYTGPNGSHFGFSLDFYKDS
HGSVAIVVGAPRTLDQSRKETGGVFLCPWRAEGGQCSSLPFDLNDEIRKIDSQTFQTFKA
RQGLGASVVSWNDNIVACAPWQHWNALHKNEETEKTPVGGCFVAQLRNGGRAEYSPCRDN
TMSGIYVASRFNNDKRYCEVGFSSAVTEAGELVLGAPGGYFFVGLLVRAPIADIISSYHP
STLLWNVGTQSATFDSGNPEYFDGYRGYSVAVGEFDGDLSTTEYVFGAPTWSWTLGAVEI
LNSYYQTLQRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRNLAEVGRVY
LFLQPRGPYVLGAPSLLLTGTQLYGRFGSAITPLGDLNRDGYNDIAVAAPYGGSSGRGQV
LVFLGQSEGLSSRPSQVLDSPFPTGSGFGFSLRGATDIDDNGYPDLLVGAYGANKVAVYR
ALPVVMTTVQLLVQDSLNPAVKKCVLPQTKTPVSCFNIQMCVGATGYNIPQKLFLNAELQ
LDRQKPRQGRRVLLLSSQQAGTTLHLDLGGRHSPICHTTTAFLRDEADFRDKLSPIVLSL
NVSLQPEKDGIAPALVLHGDTHVQEQTRIILDCGEDDLCVPQLQLTANVRGSPLLIGADN
VLELQMDAANEGEGAYEAELVVHLPPGAHYMRALSNMEGFERLVCNQKKENETKVVLCEL
GNPMKRNAQIGITMLVGVENLEEAGEHVSFQLQIRSKNSQNPHSETVLLDVPVRAEAHVE
LRGNSFPASLVVVAEEGNRQNSSNSQGPKVEHTYELHNKGPGTVSGLRLYLCLPGQSQPS
DLLYILDIQPQGGLQCSSQPSLNPLKLDWGLPTPSPSPQAHHKRERRQVFLPEQKQPSRL
QDPVLVSCDSAPSTVVHCELQEMARGQRVMVTVRAFLWLPSLHQRPLDQFVLQSHAWFNV
SSLPYAVPALRLPSGEVQVETQLFRVLEERDIPMWWVLVGVLGGLLLLTLLVLAMWKVGF
FKRNRPPLEADEEGE
NT seq 3108 nt   +upstreamnt  +downstreamnt
atggtcagagctttgtgtccatttcatgccctctggcttctggagtgggtgcagctactc
ttgggacctggcgctgcccctccaacctcagccttgaacctggacccagtgcagctcacc
ttctacacgggccccaatggcagtcattttgggttttcactggacttctacaaggacagc
catgggagcgtggccatcgtggtgggcgccccgcggaccctagatcaaagccggaaggag
acgggcggcgtgttcctgtgcccctggagggcagagggaggccagtgctcctctttgccc
ttcgatctcaatgatgagatacgaaagatagactcccaaactttccaaaccttcaaggcc
cggcaaggcctaggggcgtcggtcgtcagctggaacgacaacattgtggcctgcgccccc
tggcagcattggaacgccctacataagaacgaggagactgagaagacacccgtaggtggc
tgcttcgtggctcaactccggaacggcggccgcgcggagtactcgccctgccgggacaac
accatgagcgggatttatgtggcaagtcgcttcaacaacgacaagcgctactgtgaagtg
ggcttcagctccgcggtcactgaggctggagagctggtgcttggggcccctggcggctat
tttttcgtaggtctcctggtgcgggcgccaattgcggatatcatctcgagttaccacccg
agcaccctcttgtggaacgtgggcacccagagtgccaccttcgactccggcaacccagag
tacttcgacggctaccgggggtactcagtggccgtgggcgagtttgacggggatctcagc
actacagagtatgtgttcggtgcccctacctggagctggaccctgggagcggtggaaatt
ttgaactcctactaccagacgctgcaacggctgcatggagagcagatggcttcgtatttc
gggcactcggtggcagtcactgacgtcaacggggacgggaggcacgacctgctggtgggg
gcgccactgtacatggagagccgcgcggaccgcaatctggccgaggtggggcgcgtgtat
ctgttcctgcagcctcgaggtccctatgtgctgggcgctcccagcctcctgctgactggc
actcagctctacgggcgattcggctcagccattacgcctctgggcgacctcaaccgggat
ggctacaacgacattgcagtggccgctccatatgggggttccagcggtcggggccaggtg
ctggtgttcctgggtcagagtgaggggcttagctcacgcccctcccaggtcctggacagc
cccttccccacaggctctggcttcggcttctccctgcgaggtgccacagacatcgatgac
aatggatacccagacctactggtgggagcttatggggccaacaaggtggctgtgtacaga
gccctgcccgtggtgatgaccactgtccagctgctggtgcaagattctctgaatcctgct
gtgaagaaatgtgttctgccccagacgaagacaccagtgagctgctttaatatccagatg
tgtgtgggagccactgggtacaacattcctcagaagctgttcttgaatgccgagctgcag
ctggaccggcagaaaccccgccagggccggcgagtgctactgctgagctctcaacaggca
ggcaccaccctgcacctggatctgggtgggaggcacagccccatctgccacaccaccact
gctttcctccgagatgaggctgacttccgggacaagctgagccccatagtgctcagcctc
aatgtgtccctgcagcccgagaaggatggaatagcccctgctcttgtgctacatggagat
acccacgtccaggagcagacccgaatcatcctggactgtggggaagatgacctgtgtgtg
ccccagctccagctcactgccaacgtgagaggttctccactcctaattggagctgataat
gtgctggagctgcaaatggacgcagccaatgagggtgagggggcctatgaggctgagctg
gttgtacacctgcccccaggtgctcactacatgcgggccctcagcaacatggagggtttt
gagaggcttgtctgtaaccagaagaaagagaatgagaccaaggtagtgctgtgtgagctg
ggcaaccccatgaagaggaatgcccagataggaatcacaatgttggtgggtgtggagaac
ctggaggaggctggggagcatgtgtccttccagctgcagatcaggagcaagaacagccag
aatcctcacagtgagactgtgcttttggatgtgccagtccgggcagaggcccatgtggag
ttgcgagggaactcctttccagcctccctggtagtggtggcagaagaaggcaacagacag
aatagctccaacagccagggccccaaagtggagcacacctatgagctccacaacaaaggc
cctggtactgtaagtggcctccgcctctacctctgcctccctggccagtcccagccctct
gacctgctctacatcctggacatacagccccaggggggacttcagtgctcctcacagccc
tctctcaacccactgaagctggactggggtctgcccacccccagcccttccccccaggcc
catcacaagcgggagcgcagacaggtgttcctgccagagcagaaacaaccctcgaggctt
caggatccagttcttgtgagctgcgactcggcgcccagtactgtggtgcactgtgagctg
caggagatggcacgcgggcagcgggtcatggtcaccgtgagagccttcctgtggctgccc
agccttcaccagaggcccctggaccagtttgtgctgcagtcccacgcttggttcaatgtc
tcttccctcccctacgccgtgcctgccctccgcctgcctagtggggaagttcaggtggag
acgcagctgtttcgggtcttggaggaaagagacattcccatgtggtgggtgctggtgggt
gtgcttggtggcttgctgttgctcacactcctggtgctggccatgtggaaggttggcttc
ttcaagaggaatcggccgcccctagaagcagatgaggagggagagtga

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