Methanopyrus kandleri: MK0892
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Entry
MK0892 CDS
T00078
Name
(GenBank) Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis; translation initiation factor eIF2B subunit
KO
K23144
UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:
2.7.7.23
2.7.7.24
2.7.7.83
2.3.1.157
2.3.1.276
]
Organism
mka
Methanopyrus kandleri
Pathway
mka00520
Amino sugar and nucleotide sugar metabolism
mka00521
Streptomycin biosynthesis
mka00541
Biosynthesis of various nucleotide sugars
mka01100
Metabolic pathways
mka01110
Biosynthesis of secondary metabolites
mka01250
Biosynthesis of nucleotide sugars
Module
mka_M00909
UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
mka00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
MK0892
00541 Biosynthesis of various nucleotide sugars
MK0892
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
MK0892
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
MK0892
00525 Acarbose and validamycin biosynthesis
MK0892
Enzymes [BR:
mka01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.157 glucosamine-1-phosphate N-acetyltransferase
MK0892
2.3.1.276 galactosamine-1-phosphate N-acetyltransferase
MK0892
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.23 UDP-N-acetylglucosamine diphosphorylase
MK0892
2.7.7.24 glucose-1-phosphate thymidylyltransferase
MK0892
2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase
MK0892
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Paralog
Gene cluster
GFIT
Motif
Pfam:
NTP_transferase
Hexapep
NTP_transf_3
LbH_EIF2B
GMPPB_C
Hexapep_GlmU
IspD
Fucose_pyrophosphorylase
DUF6564
DUF4954
Motif
Other DBs
NCBI-ProteinID:
AAM02105
UniProt:
Q8TWY9
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Position
complement(839829..841106)
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AA seq
425 aa
AA seq
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MIGIVLAAGEGTRMRPLTKTRPKVLLPVADRRLIDFSIEAMKRIGVEHLVVVVEYLAEKV
ERYVKDRWGDSFELEFVRQGKPLGTAHAVYVAWREIEPDETVVITNGDLVFDSELLERAV
REHEGVASMVLVEVEDPSEFGVARLQDGYVVELVEKPKPEEAPSNLANAGVYVAEPEFER
FLERVKPSPRGEFEITDALLDAAIDEGVLGISYDGFWSDVGRPWDLLDANAWALRNAMSR
PEVEGVIEENVELRGPVWVAEDAILRSGAVVEGPAYIGPGCEIGPNCYIRPATTLVRDVR
IGQAVEIKNSIIMEGTNVSHLSYVGDSVIGAKCNLGAGTIIANLRHDERNVKVVVKGELE
DTGRRKFGAVLGDGVKTGINTSILPGRKLGPYSATAPSTVVRKNVPEGKMLVQGDQILVD
WEGRG
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgatcggtatcgtgctcgcggcgggcgaaggtacccggatgcgaccgctgacgaagaca
cggccgaaggtcctcctgccggtggccgatcgccgtcttatcgacttctccatcgaggcc
atgaagcgcatcggagtggaacacctcgtggtggtcgtggaatacctggccgagaaggtg
gaacggtacgtcaaggatcgctggggcgattccttcgagctggagttcgtccgtcagggt
aagcccctgggaacagcccacgctgtgtacgtcgcgtggcgggagatcgaacccgacgag
accgtggtcatcacaaacggggacttggtgttcgattcggagttgctcgagcgcgcggta
cgtgagcacgaaggcgtcgcctcaatggtgctagtggaggtcgaggatccgtcggaattc
ggggtcgcgagactacaagacgggtacgtggtggagctcgtggagaaacccaagcccgag
gaggctccctccaacctggcgaacgcgggagtgtacgtggcggaaccggagttcgagagg
tttttggaacgagtcaaaccctctccgcggggcgagttcgagatcaccgatgcgctgctc
gacgccgccatcgatgaaggtgttctagggatttcgtacgacgggttctggtccgacgta
ggtcgcccgtgggacctactcgacgccaacgcttgggcacttcggaacgcgatgtcgcgt
cccgaggttgaaggagtcatcgaggagaacgtggagctgagaggaccggtgtgggtagcc
gaggatgcgatcctcaggtcgggagccgtagtcgaagggcccgcctatataggcccgggg
tgcgaaatcggacccaactgctacatccgaccggcgacgacgctggtccgggacgtccgc
atcggccaagccgtcgaaatcaagaactcaataatcatggaggggacgaacgtcagccac
ctctcctacgtgggagacagcgttatcggggccaagtgcaacctgggagccggtaccatc
atcgccaacctcagacacgatgaacgcaacgtgaaagtagtagtcaagggcgagctcgag
gataccggtaggaggaagttcggagccgtactgggtgatggggttaaaacagggatcaac
acctctatactgccgggacggaaactgggcccgtactcggccaccgcaccttccaccgtc
gtccgtaagaacgtcccggagggcaagatgctagttcaaggtgaccagatcctagtcgat
tgggagggacgcggatga
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