Methanopyrus kandleri: MK1440
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Entry
MK1440 CDS
T00078
Symbol
leuC_1
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mka
Methanopyrus kandleri
Pathway
mka00290
Valine, leucine and isoleucine biosynthesis
mka00660
C5-Branched dibasic acid metabolism
mka01100
Metabolic pathways
mka01110
Biosynthesis of secondary metabolites
mka01210
2-Oxocarboxylic acid metabolism
mka01230
Biosynthesis of amino acids
Module
mka_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mka_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mka00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MK1440 (leuC_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MK1440 (leuC_1)
Enzymes [BR:
mka01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MK1440 (leuC_1)
4.2.1.35 (R)-2-methylmalate dehydratase
MK1440 (leuC_1)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AAM02653
UniProt:
Q8TVF2
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Position
complement(1472310..1473566)
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AA seq
418 aa
AA seq
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MGKTMAEKILSRASGEDAEAGDIVVANIDVAMVHDITGPITVQRLEEMGVERVWDPSKIV
VLFDHQVPADSVEAAENHKIMREFVEEQGIEHFYDVREGVCHQVLPEKGHVRPGDVIVGA
DSHTCTHGALGAFATGIGSTDMAAVFATGKLWFRVPETYRVEITGELPEGVYAKDVVLKV
TGEIGADGATYMAIEYHGEVVREMSVSDRMCLCNMAIEMGAKTGMVPPDEKTLEYVKKRA
GTEGRPVEPDPDARYEAELTLDVSDLEPQVAKPFSPDNVVPVGEVEGIAIDQVFIGSCTN
GRYEDLKVAAEVLEGEEVHDDVRLIVIPASREVYHRTLKDGVLEVLHEAGALICPPNCGP
CLGGHMGVLAEGERCVATSNRNFPGRMGHRESEVYLASPATAAASAIEGEITDPRPYL
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
gtggggaagacgatggccgagaagatactgtctcgagcgtccggagaagacgctgaggcg
ggggatatcgtcgtcgccaacatcgacgtggcgatggtccacgatatcacgggcccgatc
acggttcagcggctcgaggagatgggagtcgagcgcgtgtgggacccgtccaagatcgtc
gtgctgttcgaccatcaggtgcccgcggactccgtggaagccgcggagaaccacaaaata
atgcgggagttcgtcgaagaacagggtatcgagcacttctacgacgttcgggagggtgtc
tgtcaccaggtcctccccgagaagggtcacgtgcgtcccggggacgtgatcgtgggggcc
gactctcacacctgcacccacggagcgctcggagccttcgccaccgggatcggttccacc
gacatggcggcggtctttgcgaccggtaagctgtggttccgcgtcccggaaacttaccgc
gtagagatcacgggagagcttccggaaggtgtgtacgcgaaggatgtcgtgctcaaggtg
acgggagaaatcggtgccgacggtgcgacgtacatggcgatcgagtaccacggcgaggtc
gtccgagagatgtccgtatcggaccgtatgtgcctgtgcaacatggcgatcgagatggga
gcgaagacgggaatggttccacccgacgagaagacgctcgagtacgtcaagaagcgtgcg
ggtacggaagggcgcccggttgagccggacccggacgcccggtacgaggccgagctgacc
ttggacgtgagcgacctcgagccgcaggtcgcgaagccgttctctccggacaacgtggtg
cccgtgggggaggtcgaaggtatcgcgatcgaccaagtcttcatcggttcctgtaccaac
ggtcggtacgaggacctgaaggttgcggcggaggtacttgaaggcgaggaggtccacgac
gacgtccggctgatcgtcatcccggcgtcgagggaagtttaccaccggacgctcaaggac
ggcgtgctcgaagtactccacgaggcgggggcactgatctgcccgccgaactgcggtccg
tgcctgggtggccatatgggagtgctagcggaaggcgagcgatgcgtagcgacgtccaac
aggaactttccgggtaggatgggacaccgcgagtcggaagtgtatctagccagtccggcg
acggccgccgccagcgctatcgagggtgagatcaccgaccctcgtccctacctctaa
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