Mycobacterium sp. KMS: Mkms_0273
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Entry
Mkms_0273 CDS
T00442
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
mkm
Mycobacterium sp. KMS
Pathway
mkm00860
Porphyrin metabolism
mkm01100
Metabolic pathways
mkm01110
Biosynthesis of secondary metabolites
mkm01120
Microbial metabolism in diverse environments
mkm01240
Biosynthesis of cofactors
Module
mkm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mkm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mkm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Mkms_0273
Enzymes [BR:
mkm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Mkms_0273
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Peripla_BP_6
Motif
Other DBs
NCBI-ProteinID:
ABL89490
UniProt:
A1U9I2
LinkDB
All DBs
Position
complement(310107..311255)
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AA seq
382 aa
AA seq
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MSEPDWAPLTGFRVAVTSARRAEELSALLRRRGATVTSAAAIAMVPLPDDDELRAHTQAL
IDAPPDIVIATTGIGLRGWIAAADGWGVAAELTAALAGARIVSRGPKATGALRAAGLPEE
WSPDSESSREVLRYLLDGGIADKRIAVQLHGATDDWDPFPEFLDELRAAGADVVPIRVYR
WRPAPRDGDFDQLVAGIAEEKFDAVSFTSAPAVASVLMRATEMGVADRVLTALRTNVHAM
CVGPVTARPLVRLGVPTSAPERMRLGALARHITDELPLLQARTVRVAGHLLEIRGTCVLV
DGVVKSLSPAGMATIRALAHRPGAVVSRTDLLGALPGSGTDTHAVETAVLRLRTALGDKQ
IVSTVVKRGYRLTVDDDLAEAL
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atgagtgagcctgactgggcaccgctcaccggattccgggtggcggtgacctccgcccga
cgcgccgaggagctgagcgcactgctgcgccgccgcggcgccaccgtcaccagcgcggcc
gcgatcgcgatggtgccgctacccgacgacgacgaactgcgcgcccacacccaggcactg
atcgacgcaccgcctgacatcgtgatcgcgaccaccgggatcgggctgcgcggctggatc
gccgccgccgacggctggggcgtcgccgccgaactcaccgcggccctggcgggggcccgc
atcgtctcccgcggacccaaggcgaccggcgcgctccgggccgccggcctgcccgaggag
tggtcaccggattcggagtcgtcccgggaggtgctgcgctatctgctcgacggcggcatc
gccgacaagcgcatcgccgtccagttgcacggcgccaccgacgactgggaccccttcccc
gaattcctcgacgaactgcgggccgcgggcgccgacgtggtgccgatccgggtgtaccgc
tggcgtccggcaccccgcgacggcgacttcgaccagttggtggcgggcatcgccgaggag
aagttcgatgccgtcagcttcacctccgcaccggctgtggcgtcggtgctcatgcgggcc
accgagatgggtgtcgccgaccgggtgctgacggccctgcggaccaacgtgcacgcgatg
tgcgtcggcccggtcaccgcgcgtcccctggtccggctcggggttccgacgtcggcgccg
gagcgcatgcggttgggtgcgctggcccgccacatcaccgacgaactgccactgttgcag
gcccgcaccgttcgggtggccggacacctgctcgagatccgcggtacctgcgtactcgtg
gacggtgtggtcaaatcgctgtccccggccgggatggccaccatccgcgcactcgcgcac
cggcccggcgcggtggtgtcgcgcaccgacctgcttggcgcattgcccggcagcggcacc
gacacccacgctgtcgagaccgcggtgctgcggctgcgaaccgcgttgggcgacaagcag
atcgtctccacggtcgtcaaacgcggataccggctcaccgtcgacgacgatctggcggag
gccctgtga
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