Mycobacterium sp. KMS: Mkms_2022
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Entry
Mkms_2022 CDS
T00442
Name
(GenBank) branched-chain alpha-keto acid dehydrogenase E1 component
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mkm
Mycobacterium sp. KMS
Pathway
mkm00280
Valine, leucine and isoleucine degradation
mkm00640
Propanoate metabolism
mkm00785
Lipoic acid metabolism
mkm01100
Metabolic pathways
mkm01110
Biosynthesis of secondary metabolites
mkm01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mkm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Mkms_2022
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Mkms_2022
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mkms_2022
Enzymes [BR:
mkm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Mkms_2022
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Gene cluster
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DUF7528
Motif
Other DBs
NCBI-ProteinID:
ABL91221
UniProt:
A1UEG3
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All DBs
Position
2141202..2143367
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AA seq
721 aa
AA seq
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MADTSREGVDEHFTTSISQLTAISSRASGPGDRELLSLFDVALASRHLDLAARWLRAQGR
GYYTIGSSGHEGNAAVAAALRPTDPALLHYRSGGFFLARAQQVDGGLARGIRDVLLGLVA
ATDEPISGGRHKVFGRADLNIIPQTSTIASHLPRAVGVAFSTARAGKLGVPCRWPADAVT
VCSFGDASVNHSTAVGALNTAMHTAYQGMPMPLLFVCEDNGIGISTRTPRGWVARTYSQR
EGLQYFAADGSDLAATLETTRAAAEFVRTHRRPAFLHLSTVRLMGHAGSDYEPGYRRPDE
IVADFDRDPVLCAAKASVAQGILSPVEVLERYEATRRQVLDMAAEVRDAPQLDSAAAVER
PLRETLAEAVAASSAPPPGGSLAPPVTVAQAVNRALADALAHHPEALVFGEDVARKGGVY
GVTRGLQQKAGPARVFDTLLDEQAILGLALGAGVSGLLPIPEIQYLAYFHNAADQIRGEA
ATLQFFADRQYRNPMVVRVAGYGYQKGFGGHFHNDNSIAAMRDIPGVVIASPARPDDAAA
MMHACVAAAKTAGAVCLYLEPIALYHTKDLYADGDGQWLAPLTGTPAPIGRARIHGDGAA
LTILTFGNGLWMSLRVARRLERLHIGARIVDLRWLAPLPVEDMLREAQATGRVLIVDETR
ETGGVGEGILAALLAHGYTGPVERVAGRDSFIPLGDAALAVLLSEDTIEAAAIKLARTAG
S
NT seq
2166 nt
NT seq
+upstream
nt +downstream
nt
gtggctgacacctcccgcgagggcgtcgacgaacacttcacgacatcgatctcgcaactg
accgcgatctcgtcgcgggcctccgggccgggagatcgagagttgttgtcgctgttcgac
gttgcgctggccagccgccacctcgacctggccgcgcggtggttgcgcgcgcagggccgc
ggttactacacgatcggatcgtccggtcacgagggcaacgccgcggtggccgcggcgctg
cgacccaccgacccggcgctgctgcactaccgctcgggcgggttcttcctggcgcgcgcc
cagcaggtcgacggcgggctggcgcgcgggatccgggacgtgctgctcgggctggtcgcg
gcgaccgacgagccgatctccggtggtcggcacaaggtgttcggccgcgccgacctgaac
atcatcccgcagaccagcacgatcgcctcgcaccttccgcgggcggtcggggtggcgttc
tcgacggcccgcgccggcaaactcggcgtgccctgccgctggccggccgacgcggtcacg
gtgtgcagtttcggcgatgcctcggtcaaccactcgacggcggtcggtgcgctcaacacc
gccatgcacaccgcctaccagggcatgccgatgccgctgctgttcgtgtgcgaggacaac
gggatcggcatctccaccaggaccccgcggggctgggttgcgcgcacatactcgcagcgt
gaggggctgcagtacttcgccgccgacggatccgacctggcggcgaccctcgaaaccacg
agggctgcagccgaattcgtgcggacacaccgtcgtcccgcctttctgcatctgagcacg
gtgcggctgatgggtcacgccggatccgattacgaaccgggttaccgccgccccgacgag
atcgtcgccgacttcgatcgcgaccccgtgctgtgtgccgcgaaagcatctgtcgcgcag
ggcatcctgtcgccggtggaagttctcgagcgctacgaggccacccgtcgccaagtgctc
gacatggccgccgaggtcagggacgccccgcagttggacagtgcggccgccgtcgaacgg
ccactgcgcgagaccctcgccgaggcggtcgccgcgtcgagcgccccgccgccgggtggg
tcgttagccccgccggtgacggtggcccaagccgtcaaccgcgcactggccgatgcgttg
gcccaccaccccgaggcgctggtcttcggtgaggatgtggcgcgcaagggcggcgtgtac
ggcgtcacccgcggactgcagcagaaggccggcccggcccgggtgttcgacaccctgctc
gacgaacaggccatcctcggcctcgccctcggcgcgggggtgtccggcctgctgccgatc
cccgagatccagtacctggcgtatttccacaacgccgccgaccagatccgcggcgaggcc
gccacgctgcagttcttcgccgaccggcaataccgcaaccccatggtcgtgcgggtcgcc
ggctacggctaccagaagggtttcggcgggcacttccacaacgacaactcgatcgcggcg
atgcgcgacatccccggcgtggtgatcgcctccccggcgcgcccggacgacgccgccgcg
atgatgcacgcatgcgtggccgcggcgaagacggcgggggcggtctgcctctacctcgag
ccgatcgcgctgtaccacaccaaggatctgtacgccgacggcgacggccagtggctggcg
ccgctgaccgggacgcccgccccgatcggccgggcgcgcatccacggcgacggtgccgca
ctgacgatcctcaccttcggcaacggactgtggatgagcctgcgggtggcgcggcggctc
gaacgcctgcacatcggtgcccgcatcgtcgatctgcgctggctcgcgccgctgcccgtc
gaggacatgctccgcgaagcccaagccaccggccgggtgctcatcgtcgacgagacccgc
gagaccggcggggtgggcgaaggcatcctcgccgcactgctcgcccacggatacaccggg
ccggtcgagcgggtggccggccgcgacagcttcattccgctcggtgacgccgcactcgcg
gtactgctgagcgaggacaccatcgaggcggcggccatcaagctggcccgcactgccggc
agttga
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