Mycobacterium kansasii ATCC 12478: MKAN_04190
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Entry
MKAN_04190 CDS
T02887
Name
(GenBank) pyruvate dehydrogenase E1 subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mkn
Mycobacterium kansasii ATCC 12478
Pathway
mkn00010
Glycolysis / Gluconeogenesis
mkn00020
Citrate cycle (TCA cycle)
mkn00620
Pyruvate metabolism
mkn00785
Lipoic acid metabolism
mkn01100
Metabolic pathways
mkn01110
Biosynthesis of secondary metabolites
mkn01120
Microbial metabolism in diverse environments
mkn01200
Carbon metabolism
mkn01210
2-Oxocarboxylic acid metabolism
Module
mkn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mkn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MKAN_04190
00020 Citrate cycle (TCA cycle)
MKAN_04190
00620 Pyruvate metabolism
MKAN_04190
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MKAN_04190
Enzymes [BR:
mkn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MKAN_04190
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AGZ49575
UniProt:
U5WNJ2
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All DBs
Position
949353..950360
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AA seq
335 aa
AA seq
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MTDTKLAQELLADMVRVRRMEEKCAELYSAAKIRGFLHLYVGEEAVAAGSLRALAEDDAV
VATYREHAHALLRGIPMTSIMAEMFGKQEGCSRGRGGSMHLFDKSRRFYGGNAIVAGGLP
LAVGVALADAMLKRNRVTACYFGDGAVAEGAFHESLNMAALWNLPVLFLCENNLYAMGTA
LDRAQSQTDLTVKAASYKVPTLAVDGMDVEACLNATQQGVDHVRNTGGPFFIEFRTYRFR
AHSMFDPELYRDKAEVQRWRERDPIRLFTEQCLDSGTLTDDDVREIEDAAAAEIEAAVAY
AEAGTWEDPADLARDVLTPVGESTAADESTWEPTR
NT seq
1008 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgatacgaagctggcgcaggaactgctggcggatatggtccgggtgcgccggatg
gaagaaaaatgcgcagaactctacagcgcggccaagattcgggggttcctgcatctctac
gtcggcgaggaggccgtggccgccggttccctgcgcgccctggccgaggacgacgcggtg
gtggcgacctaccgcgaacatgcgcacgcgctgctgcgcggtatcccgatgacctcgatc
atggccgagatgttcggcaagcaggagggctgctcgcgcggccgcggcgggtcgatgcac
ctgttcgacaagtccaggcggttctacggcggcaacgcgattgtggccggcggcctgccg
ctggcggtgggtgtcgcgctcgccgacgcgatgctgaagcgaaaccgcgtgacagcatgc
tatttcggcgacggcgcggtcgccgagggcgcctttcacgagtcgttgaacatggcggcg
ctgtggaacctgccggtgttgttcctgtgcgagaacaacctttacgccatgggtaccgca
ctggaccgggcgcagtcgcagaccgacctcaccgtcaaggcggcgtcgtataaggttccg
acgctggccgtggacgggatggacgtcgaggcgtgcctcaacgccacgcaacagggtgtc
gaccacgtccgcaacaccggcggcccgttcttcatcgagttccgtacctaccggttccgc
gcgcattcgatgttcgacccggaactgtaccgcgacaaggccgaagtccagcgttggcgc
gagcgcgacccgatccggctattcaccgaacagtgcctggacagcggcactctcaccgac
gacgacgtgcgcgagatcgaggatgcggcggccgccgagatcgaggccgcggtggcctac
gccgaagccgggacgtgggaagacccggccgacctcgcgcgtgatgtgctgacgccggtc
ggggagagcaccgcggccgacgaatcgacttgggagccgacgcgatga
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