Mycobacterium kansasii ATCC 12478: MKAN_05285
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Entry
MKAN_05285 CDS
T02887
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mkn
Mycobacterium kansasii ATCC 12478
Pathway
mkn00290
Valine, leucine and isoleucine biosynthesis
mkn00660
C5-Branched dibasic acid metabolism
mkn01100
Metabolic pathways
mkn01110
Biosynthesis of secondary metabolites
mkn01210
2-Oxocarboxylic acid metabolism
mkn01230
Biosynthesis of amino acids
Module
mkn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mkn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MKAN_05285
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MKAN_05285
Enzymes [BR:
mkn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MKAN_05285
4.2.1.35 (R)-2-methylmalate dehydratase
MKAN_05285
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AGZ49761
UniProt:
U5WPC4
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All DBs
Position
1191381..1192628
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AA seq
415 aa
AA seq
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MGMTILEKIFARKTGQYTVSPGDTVVVDVDMTVLIDLQFAREWIQPHRIHDPEKLAVVMD
HAVPAPTVRDAVGGQHARKFVADFGIRRFYDVGRHGISHQVIAENGLARPGEVLACSDSH
TCAAGAYNTAARGLGTDEVYSIMCTGQTWYQIAPTIRYELRGVKPDTVSGKDIFLHIASR
YGDAANRNLEYGGSGLPTIPLHDRRTIATQGAELSADFSIFEADDMVTGNLDARGIDGYR
VAAPDHDAGYHDIRTVDLATLEPYVALPGTVSRNGLPVSQLGRQAVDQAFIGSCANGQLE
DLEIAARVLRGRSIAPGVRLLVTPASQAVYREAMRRGYLQDLADSGAVVTNATCGACFGY
HMGLVGPGEVCITSSTRNYTGRMGSTAARIFMASPATVAASAVTGYITDPRSLVA
NT seq
1248 nt
NT seq
+upstream
nt +downstream
nt
atgggcatgaccatcctcgagaagatcttcgcccgcaagaccggccaatacaccgtatcg
cccggtgacaccgtcgtcgtcgatgtcgacatgaccgtgctgatcgacctccaattcgcg
cgagaatggatacagccccaccggattcacgaccctgagaaactggcggtggtgatggac
cacgccgtgccggcaccgacggtccgagatgcggtcggcggtcagcatgcccggaaattc
gtcgccgacttcggcatccggcgcttctacgacgtcggcaggcatggcatcagccatcag
gtcatcgccgagaacggactggcccggccgggagaagtactggcgtgcagtgactcccat
acctgcgccgccggagcgtacaacaccgcggcccgcggcctggggaccgacgaggtgtac
tcgatcatgtgcaccggccagacctggtaccagatcgcgccgaccatccgatacgagttg
cgtggcgtcaaaccggacaccgtcagcggcaaggacatcttcctgcacatcgccagccgt
tatggtgatgccgccaaccggaatctggaatacggcggtagcggcctacccactatcccg
ctgcacgatcggcgcaccatcgcgacccagggggccgaattatccgctgatttcagcatt
ttcgaagccgacgacatggtgaccggaaacctggacgcgcggggtatcgatggataccgc
gttgcggcgccggatcacgacgccgggtaccacgacatccggaccgtcgacctggccacg
ctcgagccgtatgtcgctcttccgggcaccgtcagccgcaatgggctgcccgtttcgcaa
ctcggcagacaggcggtcgaccaggcattcatcgggtcgtgcgccaacggtcaactcgaa
gacctcgaaatcgccgctcgggtgctgcgcggccgcagcatcgcgccgggggtgcggctg
ctggtcacgcccgcatcccaagcggtgtaccgggaggccatgcggcgcggctacttacag
gacctcgccgactccggcgccgtggtcaccaacgccacctgcggcgcctgcttcggctac
cacatgggactggtcgggcccggcgaagtgtgtatcacctcgagtacccgcaactacacc
gggcggatgggcagcacggcggcacggatcttcatggcctcaccggcgaccgtcgctgcg
tcagcggtcaccggttacatcaccgacccgaggagtctggttgcatga
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