Methylomonas koyamae: MKLM6_2119
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Entry
MKLM6_2119 CDS
T05118
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mko
Methylomonas koyamae
Pathway
mko00230
Purine metabolism
mko01100
Metabolic pathways
mko01110
Biosynthesis of secondary metabolites
Module
mko_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mko00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MKLM6_2119
Enzymes [BR:
mko01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MKLM6_2119
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ATG90347
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Position
2343226..2347113
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AA seq
1295 aa
AA seq
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MLILPGTSALSRFRIEKLLGDLQAIDAGIVGIDARFQHFVQLDADLSPAQQAMLARLLDY
GDAADHAPAAGAGLEPAGVLWVVPRLGTISPWSSKASEIAERCGLTAVKRIERGIEYRFF
SGAALADDVKQNIAAVLHDRMTQQVVSDPTGLDLFAKHEPKPLQTVAVIENGRAALEQAN
AALGLALSADEIDYLADSFTRLGRNPTDVELMMFAQANSEHCRHKIFNASWSIDGEEQAK
SLFAMIRNTHNLHPQGVLSAYKDNASVLAGPSAQVFIRHADSHRYGYVEEAAHILMKVET
HNHPTAISPHPGAATGSGGEIRDEGATGRGSQTKAGLTGFSVSHLKIPGFAQPWEADNGK
PERIASALNIMLEGPIGGAAFNNEFGRPNLAGYFRSFEQPAESGEANHFRGYHKPIMIAG
GMGNIRPMLVEKQPIPAGALIVILGGPAMLIGLGGGAASSQTSGASAAELDFASVQRENP
EMQRRCQEVINHCNSLGEDTPIVSIHDIGAGGLSNAVPEIIHDAGKGGRFELRKVQNADK
GMSPMQIWCNEAQERYVVAIKPESLELFQSFCEREHCLYAVIGHATDEEHLTLSDEWFGQ
SSPIDLPMSVLFGKPPKMHRDVKRLHKVLPDLALDQVELAEAVKRVLAFPAVADKSFLIH
IGDRSVTGLVARDQMVGPWQVPVADVAVTASGFRAYTGEAMAMGERTPLALIDGPASGRM
AIGEALTNLAAARIGNLNDVKLSANWMAACGSPGEDAALFDTVKAVGMELCPALGIAIPV
GKDSLSMKTVWQDGGKDKIMTSPLSLIITAFAPVLDVRNTLTPELKNEDSVLLLIDLGQG
KNRLGGSVLAQVYNQLGSQAPDLDDASLFKRFFDTIQALNEQGLILAYHDRADGGLLATV
AEMLFAGRKGVDLDLSDLPGDTLSGLFNEELGAVLQIKNSDLHQVARLLDQAGLDDDSYV
IGRVVEGQHLRIFKAGRELYSASRAELQQTWSEVSYRMQALRDNPDCARQQFERIADDND
PGLTAQLTFDPNDDIAAGFVGQARPKVAILREQGVNGHVEMAAAFDRAGFDAIDVHMTDV
IGGRVSLSEFKGLVACGGFSYGDVLGAGGGWAKSILFNAKARAEFAAFFARLDTFGLGIC
NGCQMMSGLKDIIPGAEHWPAFKRNLSEQFEARVAMVKIQASPSIFFTGMAGSLLPVVVA
HGEGRAEFGSANPAQAQVALSYVDNYGQVTAAFPANPNGSPLGITGLTTADGRFTIMMPH
PERCFRAVQNSWHPADWAEDGAWMRMFRNARAWVG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgttgatccttcccggcacctccgcattgtcccgtttccgtatcgaaaaattgctcggc
gatttacaggctatcgacgccggcatcgtcggcatcgatgcgcgctttcaacatttcgtg
caactcgacgccgatttaagcccggcgcaacaagccatgctggcgcgtttgctcgactac
ggcgacgccgccgaccacgcgccagccgccggcgccggcctcgaaccggccggggtacta
tgggtggtgccgcgattggggacgatttcgccgtggtcgagcaaggcgtccgaaatcgcc
gagcgttgcggtttgaccgcagtgaagcgcatcgagcgcggcatcgagtaccggtttttt
agcggcgcagcgctggccgatgacgttaaacaaaatatagcggcggtattgcacgacagg
atgacccagcaggttgtatcggacccaactgggttggacttgttcgccaagcacgaaccc
aagccgttacaaaccgttgccgttatcgaaaacggccgggccgcattggaacaagccaat
gccgcattgggcctggccttgtcggccgacgagatcgattacttggccgacagcttcacc
cgattgggccgcaacccgaccgacgtcgagttgatgatgttcgcccaggccaattccgag
cattgccgccacaaaatcttcaacgccagttggagcatagacggcgaagaacaggctaag
tcgctgttcgcgatgatacgcaacacacacaatctgcatccgcaaggcgtgttgtcggct
tataaagacaatgcctcggtgctggcgggtccctccgcgcaggttttcatccgccacgcg
gatagccaccgatacggctatgtcgaggaagctgcgcacattttgatgaaggtcgagacc
cacaaccacccgacagcgatttccccgcatccgggcgcggccacgggttccggcggcgag
atccgcgacgaaggcgcgaccggccgcggctcgcagaccaaggccggtctgaccgggttc
agcgtgtcgcatttgaaaatccccggtttcgcccaaccctgggaggccgacaacggcaag
ccggagcgcatcgcctcggcgctgaacatcatgctggaagggccgatcggcggcgcggcg
ttcaacaacgaattcggccggcccaatctggccggctatttccgcagcttcgagcagccg
gccgaaagcggcgaggccaaccattttcgcggttaccacaaaccgatcatgatcgccggc
ggcatgggcaacattcggccgatgctggtcgagaaacaaccgattccggccggtgcgttg
atcgtaattttgggcggcccggccatgctgatcggcttgggcggcggcgcggcctcgtcg
caaacctccggtgccagcgcggccgagctggatttcgcctcggtgcaacgcgaaaacccg
gaaatgcagcgccgttgccaggaagtcatcaaccactgtaactcgctgggcgaggacacg
ccgattgtctctatccacgacatcggtgccggcggcttatccaacgcggtgccggaaatc
atccacgacgccggcaaaggcggccgcttcgaattgcgcaaggtgcaaaacgccgacaag
ggcatgtcgccgatgcaaatctggtgcaacgaggctcaagaacgctacgtggtggcgatc
aagccggagtcgctggaactgttccaaagcttttgcgagcgtgagcattgtctatacgcc
gtgatcggccacgccaccgacgaagaacatttaacgctgagcgacgagtggttcggccaa
tcgtcgcctatcgatctaccgatgtcggtgttgttcggcaaaccgccgaaaatgcaccgc
gacgtgaagcggctgcacaaagtcttgccggatttggctttagatcaagtcgagctggcg
gaagcggtcaaacgggtgttggcgtttccggccgtggccgataaaagtttcctgatccac
atcggcgaccgttcggtcaccggtctggttgcgcgcgaccagatggtcgggccgtggcag
gtgccggtggccgatgtcgccgtgaccgcatccggattccgggcttataccggtgaggcg
atggcgatgggcgagcgcacgccgctggccttgatcgacgggcccgcctccggccggatg
gcgataggcgaagccttgaccaatttggccgccgcgcgcatcggtaatttgaacgacgtc
aaactgtccgccaactggatggcagcttgcggcagccccggcgaagacgcggccttgttc
gatactgtgaaagcggtcggcatggaattgtgtccggcactgggtatcgcgattccggtc
ggcaaggactcgttgtcgatgaaaaccgtctggcaggacggcggcaaagacaaaatcatg
acctcgccgctgtcgttaatcatcaccgccttcgcgccggtgctggacgtacgcaacacg
ctgacgccggaactgaagaacgaagacagcgtattgctgttgatcgatctgggccaaggc
aaaaaccgcctcggcggctcggtattggcgcaagtttacaaccagctcggcagccaggcc
cccgacttggacgatgccagcctgttcaaacgtttcttcgacaccatccaagccctaaat
gagcaaggcctgatcctggcctaccacgaccgggccgacggtggcttactggcgacggtt
gcggaaatgctgttcgccggccgtaagggcgtcgatctggacttgtccgatttgcccggg
gatacgctttcagggctgttcaacgaagagttgggcgcggtgttgcaaatcaaaaacagc
gatttgcatcaagtcgcccggctgttggatcaggccggcctggacgacgacagttacgtg
attggtcgcgtcgtcgaaggccagcatttgcgaatcttcaaagccggtcgggagctctat
agcgcgtcgcgcgccgagttacagcaaacctggtcggaagtcagctaccggatgcaggcc
ctgcgcgacaatccagattgcgcccgccagcaattcgagcggattgccgacgataacgat
cccggtctgaccgcgcaactgacttttgacccgaacgacgatatcgccgccggctttgtt
gggcaagcaaggccgaaagtagcgattctgcgcgagcagggcgtcaacggccacgtcgag
atggcggcggctttcgaccgggctggcttcgatgccatcgacgtacacatgaccgacgtc
atcggcggccgagtcagtctgagcgagttcaaaggcctggtggcctgcggcggcttttcc
tacggcgacgtgctgggtgccggcggcggctgggccaagtcgatattgttcaatgccaag
gcccgggccgaattcgctgcgttcttcgctcgtctggatacctttggcctgggcatttgc
aacggctgccagatgatgtccggcttgaaggacatcatccccggcgccgaacattggccg
gcgttcaaacgcaacctgtccgagcagttcgaggcgcgggtggcgatggtcaaaatccag
gcctcgccgtccattttctttaccggcatggcgggttcgctgctgccggtggtcgtcgcc
cacggcgagggccgggcggaattcggctcggcgaatccggcgcaagcgcaggtcgcgctc
agctacgtcgacaactatggccaagtaaccgcggccttcccggccaatcccaacggttcg
ccgctcggcatcaccggcctgaccactgcggacggccgtttcaccatcatgatgccgcat
ccggaacgttgtttcagagcggtgcaaaactcctggcatccggccgattgggccgaagac
ggcgcctggatgcggatgttcagaaatgcccgggcgtgggtaggttag
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