Mycolicibacillus koreensis: MKOR_24650
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Entry
MKOR_24650 CDS
T06447
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mkr
Mycolicibacillus koreensis
Pathway
mkr00860
Porphyrin metabolism
mkr01100
Metabolic pathways
mkr01110
Biosynthesis of secondary metabolites
mkr01120
Microbial metabolism in diverse environments
mkr01240
Biosynthesis of cofactors
Module
mkr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mkr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mkr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MKOR_24650 (hemD)
Enzymes [BR:
mkr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MKOR_24650 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MKOR_24650 (hemD)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY55214
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Position
complement(2500310..2502088)
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AA seq
592 aa
AA seq
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MARQVSTRGRKPKPGRIVFVGSGPGDPGLLTTRARAALARAAVVFTDPDVPESILALVGT
DLPPAPIADAKDGAKEAAKDGATTGKDAAKAAEAAEGNDTAAAVKDTAKGKSARGAKDVA
PIPNADIRPALGGAAEVAKTLVAAARAGDDVIRLVAGDPLSVDSVVTEVTTVARTNLTFE
IVPGLPPAIAVPTYAGLPLGSSHTVADVRGDVDWAALAAAPGPLILQATASHLPDAASTL
IDYGLTEQTPCVVTAVGTTCSQRSVESTLHGLTEQNVFAGTELAEQAMSAGSPQNGPLVV
TIGKTVNNRTKLNWWESRALYGWTVLVPRTKDQAGEMSERLITYGALPIEVPTIAVEPPR
SPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFSEFGLDARAFSGVKIACVGEATADR
VRAFGIEPEMVPSGEQSSLGLLEEFPPYDDVFDPVNRVLLPRADIATETLAEGLRERGWE
IEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVSCIGP
KTAETAAEFGLRVDVRPETAAVGPLVDALAEHAARLRAEGALPPPRKKSRRR
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggctcgccaagtgagtacgcgaggccgtaaacccaagccgggccggatcgtgttcgtc
ggctcgggtccgggggacccggggctgctgaccacgcgggcccgcgcggcgctggcacgc
gccgccgtggtgttcaccgaccctgacgtgcccgagtcgatcctggcgctggtcggcacc
gacctgccgccggcgccgatcgcggacgccaaagacggcgccaaagaggccgccaaagac
ggcgccacaaccggcaaggacgcggcgaaggccgccgaggccgccgagggcaacgacacc
gccgcggccgtcaaggacaccgccaagggcaagtccgctaggggcgccaaggacgtcgcg
ccgatccccaacgccgacatccgtcccgcgctgggcggggccgccgaggtggccaagacg
ctggtcgccgccgcccgcgccggcgacgacgtgatccggctggtggccggcgacccgctg
tcggtggactcggtggtcaccgaggtcaccacggtcgcgcgcaccaacctgaccttcgag
atcgtgccggggctgccgccggcgatcgcggtgcccacctacgccgggctgccgctgggg
tcgtcgcacaccgtcgccgacgtgcgcggcgacgtggactgggcggcgctggccgccgcg
ccggggccgctgatcctgcaggccaccgcctcgcacctgcccgacgcggcgagcaccctg
atcgactacgggctcaccgaacagaccccgtgtgtggtgaccgcggtcggcaccacctgc
tcgcagcggtcggtggagtccaccctgcacgggctcaccgagcagaacgtcttcgccggc
accgagttggccgaacaggcgatgtccgccgggtcgccgcagaacggtccgctggtggtc
accatcggcaagaccgtcaacaaccgcaccaagctgaactggtgggagagccgggcgctg
tacggctggaccgtgctggtgccgcgcaccaaggaccaggccggcgagatgagcgaacgg
ctgatcacctacggcgcgctgccgatcgaggtgcccaccatcgccgtcgagccaccgcgc
agccccgcccagatggagcgggccgtcaaggggctggtcgacgggcgctaccagtgggtg
gtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcagcgaattcggcctg
gacgcccgggcgttctccggggtcaagatcgcctgcgtgggcgaggcgaccgccgaccgg
gtgcgggccttcgggatcgaaccggagatggtcccctccggggagcagtcctcgctgggg
ctgctcgaggagttcccgccgtatgacgacgtgttcgacccggtgaaccgggtgctgctg
ccgcgcgccgacatcgccaccgagaccctcgccgaggggctgcgggagcgcggctgggag
atcgaggacgtcaccgcctaccgcacggtgcgcgccgcgccgccgccggcggccacccgc
gagatgatcaagaccggcgggttcgacgcggtctgcttcacctcgagctccacggtgcgc
aacctcgtcggcatcgccggcaaaccgcacgcgcgcaccatcgtcagctgcatcgggccg
aagaccgccgagaccgccgccgagttcgggctgcgcgtcgacgtgcgtcccgagaccgct
gcggtgggcccgctggtcgacgcgctcgccgagcacgctgcccggttgcgcgcggagggg
gcgttgccgccgccacgcaagaagagccggcggcgctag
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