Mycobacterium kubicae: I2456_15470
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Entry
I2456_15470 CDS
T07774
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mku
Mycobacterium kubicae
Pathway
mku00300
Lysine biosynthesis
mku00550
Peptidoglycan biosynthesis
mku01100
Metabolic pathways
mku01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mku00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I2456_15470
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I2456_15470
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I2456_15470
Enzymes [BR:
mku01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I2456_15470
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Tox-SGS
PG_isomerase_N
Motif
Other DBs
NCBI-ProteinID:
QPI35980
UniProt:
A0AAX1J656
LinkDB
All DBs
Position
complement(3288456..3289964)
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AA seq
502 aa
AA seq
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MIDLTVAEIADIVGGELADISAAEAAQRHVTGTVEFDSRAVGPGGLFLALPGARSDGHDH
AAAAVAAGAVAVLAARPVGVPAIVVRPRTAQDGRAGVLEHDTDGSGAAVLAALAKLAKAV
AADLVAGGLTIIGITGSSGKTSTKDLVAAVLQPLGQVVAPPGSFNNELGHPWTVLRATRD
TDYLILEMSARHPGNIAALADIAQPAIGVVLNVGTAHLGEFGSREAIAKTKSELPQSVPP
SGVVILNADDPAVAAMAEVTRARVLRVSRGEATGSGPSDVWAGPVSLDALARPRFTLHTT
NAAADIQLGVYGDHQVTNAMCAAAVALECGATMQQVADALATAGPVSRHRMQVTTRADGV
TVIDDAYNANPDSMRAGLQALAWIAHDGPEQRRSWAVLGEMAELGDDAITEHDRIGRLAV
RLDVSRLVVVGTGRSMSAMHHGAVMEGSWGAETVTVPDADAALTLLRSELHPGDVVLVKA
SNAAGLGALADALVADEGAARP
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgacctgacggtcgccgagatcgccgacatcgtgggtggggaattggccgacatc
tccgccgcagaggccgcgcagcgccacgtcaccggcacggtcgaattcgactcgcgcgcc
gtcggcccgggcggcctgttcctggcgctgcccggtgcccgctccgatgggcatgaccac
gccgcggcggcggtcgcggccggtgccgttgcggtgctggcggcccgaccggtcggggtt
ccggcgatcgtggtccggccgcgaacggcccaggacgggcgggccggagtgctcgaacac
gacaccgacggatcgggggcggcggtgctggccgcgctggccaaactggccaaggcggtc
gccgctgacctggtggccggcgggctgaccatcatcggcatcaccggatcctccggcaag
acctcgaccaaagacctggtcgccgccgtgctccaaccgctgggccaggtggtggcccca
ccaggatcgttcaacaacgagctgggccatccctggacggtgctgcgggccacccgcgac
accgactacctcatcctggagatgtcggcacgtcaccccggcaacatcgccgcgctggcc
gacatcgcgcagccggccatcggagtggtgctcaacgtcggcaccgcgcacctgggcgag
ttcggttcccgcgaggccatcgccaagacgaaatccgaactgccgcaatcggttccgccc
tcgggcgtggtcattctcaacgccgacgacccggcggtggccgcgatggccgaggtgacg
cgggcgcgggtgctcagagtcagccggggcgaggcgaccggcagcggtcccagcgacgtc
tgggccgggccggtcagcctggacgcactggcccgcccccgcttcacgctgcacaccacc
aacgccgcagccgacatccagctcggcgtctacggcgatcaccaagtcaccaatgccatg
tgcgcggccgcggtcgccttggaatgcggagccaccatgcaacaggtggccgacgcgttg
gccaccgccggtccggtatcgcggcaccggatgcaggtgaccacccgcgccgacggggtg
acggtgatcgacgacgcttacaacgccaaccccgattccatgcgggccgggctgcaggcg
ttggcctggatcgcccacgacggccccgagcagcggcgcagttgggcggtgctgggggaa
atggccgagctgggcgacgacgcgataaccgagcacgatcgcatcggccggctcgcggtg
cgcttagatgtgtcacgactcgttgtcgtgggaactgggaggtcgatgagcgccatgcac
cacggcgcggtcatggaaggctcgtggggagctgagaccgtcaccgtgcccgacgccgac
gccgccctgaccctgctgcgctccgagctgcacccaggcgacgtcgtgctggtcaaggcg
tccaacgccgccggattgggcgcgctggccgacgcgctggtcgccgacgagggagccgcg
cggccatga
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