Macrotis lagotis (bilby): 141494470
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Entry
141494470 CDS
T11097
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
141494470 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlao03032
]
141494470 (TOP2B)
03036 Chromosome and associated proteins [BR:
mlao03036
]
141494470 (TOP2B)
Enzymes [BR:
mlao01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
141494470 (TOP2B)
DNA replication proteins [BR:
mlao03032
]
Eukaryotic type
DNA Topoisomerases
141494470 (TOP2B)
Chromosome and associated proteins [BR:
mlao03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
141494470 (TOP2B)
Centrosome formation proteins
Centriole proteins
141494470 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
141494470
NCBI-ProteinID:
XP_074051786
LinkDB
All DBs
Position
7:28190667..28273214
Genome browser
AA seq
1620 aa
AA seq
DB search
MKKLKKTSRQHFMNNFISFESHQQTCENNAAKKEESESSNKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQSMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKISIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEPKVKYFDGDDYTCITFQ
PDLAKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQIVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFVNCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIIESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYEDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLSRLLFPS
VDDNLLKFLYDDNQRVEPEWYMPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
DGLDPHPMLPNYKNFKGTIQEIGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLNYYSLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKRDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTTSGP
NFNYILNMSLWCLTKEKVEELIKQRDTKGRELNDLKRKSPSDLWKEDLAAFVEELDKVEA
QEREDALAGMAGKAIKGKVGKPKIKKLQLEETMPTPHGRRIVPQITSAMKADASKKLLKK
KKGDLDPTAVKVEFDDELGGAPAEGAGEDSLTASTPAPKGPKPKREKKEPGTRVRKTPLS
SNKSSAKKVKKRNPWSDDESKSESDLEETEPVIIPRDSLLRRAAAERPKYTFDFSEEEDD
ADEDDNNDLDELKVKSSPVTNDGDDEFIPSDGLDKDDYTFSPVKSKVTPEKSSHDKKNQD
FGNLFSFPSYSQKSEDDATKFDSGEEDSSPVFSSSFTLKSTEKPPSKTVAAKKAKLSSDA
PPKPKRLPKQKKVETTNSDSDSEFGIPKKTTTPKGKGRGAKKRKISGSENEGEYNPGRKT
SKSTPGKKSKKASFDQDSDVDIFQADFPPEPPSLPRTGRARKEVKYFAESDEDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaattaaagaagacaagtagacaacattttatgaataattttatctcatttgag
tctcaccaacaaacgtgtgagaacaatgctgcaaaaaaagaagaatcagaaagcagtaat
aaaaatgattcttcaaagaagttgtctgttgagagagtttatcagaagaaaacgcaactt
gaacacattctcctccggcctgatacatacattggatctgtggaaccattaactcagtca
atgtgggtttatgatgaagatgtaggaatgaattgcagagaagttacttttgtaccaggc
ttatacaaaatctttgatgaaattcttgttaatgcagctgacaataagcagagggataag
aacatgacctgtatcaaaatttctattgatcctgaatctaacattatcagcatctggaat
aatggaaaaggcattcctgtagtggaacacaaggtagaaaaagtgtatgttcctgcttta
atctttggacaacttttaacatctagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgtaatggttatggtgcaaaactttgcaatattttcagtacaaaatttacagttgaa
actgcttgtaaagaatacaaacatagttttaaacagacatggatgaataatatgatgaag
acatctgaacccaaagttaaatactttgatggagatgactatacatgtataacattccaa
ccagatctggcaaaatttaagatggaaaagctcgacaaggacattgtggccctcatgacc
agaagagcctatgacttagctggttcatgcaaaggagtcaaagtcatgtttaatgggaag
aagttgcctgtaaatggatttcgcagttacgtagacctttacgtaaaggacaaattggat
gaaactggggttgccctgaaagttattcatgaacttgcaaatgaacgatgggatgtttgt
ctcacattgagtgaaaaaggatttcagcaaatcagctttgtaaatagtattgctacaaca
aaaggtggaaggcacgtagattatgtggtggatcaaattgttggcaaactcattgaagtg
gttaagaaaaagaacaaagctggagtatcagtgaagccattccaagtgaaaaaccacata
tgggtttttgtcaactgtcttattgaaaatccaacttttgattctcagacaaaggaaaat
atgactctacaacccaaaagctttggttctaaatgtcagctatctgagaaatttttcaaa
gcagcttccaactgtggtattatagaaagtattctgaattgggtcaaatttaaagctcag
actcaactgaacaagaagtgttcgtctgtaaaatacagtaaaatcaaaggcattcccaaa
ctggatgatgcgaatgatgcaggtggtaaacattccctagagtgcacactcatattaaca
gaaggagactcagcaaaatcattagcagtttctggattaggtgtgattggacgagacaga
tatggagtctttccactcaggggtaaaattcttaatgttcgtgaagcttcacacaaacag
attatggaaaatgcagaaatcaacaatattattaaaatagttggtcttcaatataagaaa
agttatgaagatgcagaatctctgaaaaccttgcgttatggaaaaattatgattatgact
gatcaggatcaagatggctctcacataaagggcttacttattaatttcattcatcataat
tggccttcacttttgaaacatggttttcttgaagagttcatcactcctattgtaaaggca
agcaaaaataagcaggagctttccttctatagtatacctgagtttgatgagtggaagaaa
catatagaaaaccagaaggcctggaaaataaaatactacaaagggttgggtaccagcaca
gctaaagaagcaaaggaatattttgctgacatggaaagacatcggattttgtttagatat
gctggtcctgaagatgatgcagctattactctagcattcagtaagaagaagattgatgac
cgtaaagaatggttaacaaatttcatggaagatcgaagacagcgcaggttacatggcctg
ccagagcaatttttatatggtacagctacaaagcatttgacttacaatgattttatcaac
aaggagttgattcttttctcaaactctgacaatgaaagatcaataccatctcttgttgat
ggctttaaaccaggtcaacgaaaagttttgtttacctgttttaaaaggaatgataaacgg
gaagtcaaagttgctcagttggctggatcagttgctgagatgtctgcttatcatcatgga
gaacaagcactaatgatgactatagtcaatttggcccagaactttgttggaagtaacaat
attaatttgcttcaacctattggtcaatttggaactagacttcatggcgggaaagatgct
gcaagccctcgttatatttttacaatgttaagcactctgtcaaggctgcttttcccttct
gtggatgacaacctgcttaagttcctttatgatgataaccagcgggtggagcctgaatgg
tatatgcccattattcctatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaaacttcccaactatgatgccagagagattgtgaacaatgtcagacggatgttg
gatggcttggaccctcatcccatgcttccaaactataaaaattttaaaggaacaatccaa
gaaattggccagaaccaatacgctgttagtggtgaaatatttgtagtggatagaaataca
gtagagatcacagaacttccagttagaacatggacacaggtatataaagagcaggtttta
gaacctatgctgaatggaacagacaaaacaccagcattaatttctgattataaagaatat
catacagatacaactgtgaaatttgtggtgaagatgacagaagaaaaacttgcacaagca
gaagctgctggactgcataaagtctttaaacttcagaccactcttacttgtaattctatg
gtgctatttgaccatatgggatgtctgaagaagtatgagactgtgcaagatattctgaag
gagttctttgatttaaggttaaattattatagtttacgtaaggagtggcttgtgggaatg
ttgggggcagaatccaccaagctaaacaatcaagctcgcttcattctagagaagatacaa
gggaaaattactatagagaataggtcaaagagagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcggcagaagag
gaagaaacacaaaaccagcatgatgatagttcctccgattcgggcactacctcaggcccc
aattttaactacatcttaaatatgtctctgtggtgtcttactaaagaaaaagttgaagaa
ctgattaagcagagagatacaaaagggagagaactcaatgaccttaaaagaaaatctcct
tcagatctctggaaagaagatttagcagcttttgttgaagaactggataaagtggaagct
caagaacgggaggatgctttggccggaatggctggcaaagcgataaagggtaaagtgggc
aaacccaagataaagaagcttcagttggaagagaccatgcccacccctcacggcagaagg
attgttccacagattacctctgccatgaaggctgatgccagcaaaaagttgcttaagaaa
aagaagggtgatcttgatcctacagcagtaaaagtggaatttgatgatgaattaggtgga
gcaccagcagaaggggcaggagaagattccttgacagcatctactcctgcacctaaagga
cccaaacccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctctctcc
tctaataagtccagtgcaaagaaagtgaagaaaagaaacccttggtctgatgatgaatcc
aagtcagaaagtgacttggaagaaaccgaacctgtgattattccaagagattctctgctt
agaagagctgctgcggaaaggccaaaatatacttttgatttttcggaagaggaagatgat
gctgatgaagatgacaataatgatttagatgaattgaaagtaaaatcatctcctgtgaca
aatgatggagatgatgagttcattccttcagatggattagataaggatgattatactttt
tctccagtcaaatcaaaagtaactccagaaaaatcctcacacgacaagaaaaatcaggac
tttgggaacctgttctcatttccttcttattcacagaagtcagaagatgatgcaacaaaa
tttgacagtggtgaagaggattcttcccctgttttttcatcttcatttactctaaaatca
acagaaaaacctccaagtaaaacagtagctgccaaaaaggcaaagctatcttcagatgca
ccacccaagcccaaaagacttcccaaacagaagaaagtagaaactacaaactctgactca
gattcagaatttggcattccaaagaagaccacaacaccaaaaggcaaaggccgaggagca
aaaaagcggaaaatatctggctctgaaaatgaaggcgagtacaatcctggaagaaaaaca
tccaaatcaacacctggcaagaaatccaagaaggcctccttcgaccaggactcagatgtg
gacatcttccaggcagactttcctcctgaaccaccctctcttcctcggacagggcgtgcc
agaaaagaagtaaaatattttgcagagtctgatgaagatgttgattttgcaatgtttaat
taa
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