KEGG   Macrotis lagotis (bilby): 141495705
Entry
141495705         CDS       T11097                                 
Symbol
MAPK3
Name
(RefSeq) LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
mlao  Macrotis lagotis (bilby)
Pathway
mlao01521  EGFR tyrosine kinase inhibitor resistance
mlao01522  Endocrine resistance
mlao01524  Platinum drug resistance
mlao04010  MAPK signaling pathway
mlao04012  ErbB signaling pathway
mlao04014  Ras signaling pathway
mlao04015  Rap1 signaling pathway
mlao04022  cGMP-PKG signaling pathway
mlao04024  cAMP signaling pathway
mlao04062  Chemokine signaling pathway
mlao04066  HIF-1 signaling pathway
mlao04068  FoxO signaling pathway
mlao04071  Sphingolipid signaling pathway
mlao04072  Phospholipase D signaling pathway
mlao04114  Oocyte meiosis
mlao04140  Autophagy - animal
mlao04148  Efferocytosis
mlao04150  mTOR signaling pathway
mlao04151  PI3K-Akt signaling pathway
mlao04210  Apoptosis
mlao04218  Cellular senescence
mlao04261  Adrenergic signaling in cardiomyocytes
mlao04270  Vascular smooth muscle contraction
mlao04350  TGF-beta signaling pathway
mlao04360  Axon guidance
mlao04370  VEGF signaling pathway
mlao04371  Apelin signaling pathway
mlao04380  Osteoclast differentiation
mlao04510  Focal adhesion
mlao04517  IgSF CAM signaling
mlao04520  Adherens junction
mlao04540  Gap junction
mlao04550  Signaling pathways regulating pluripotency of stem cells
mlao04611  Platelet activation
mlao04613  Neutrophil extracellular trap formation
mlao04620  Toll-like receptor signaling pathway
mlao04621  NOD-like receptor signaling pathway
mlao04625  C-type lectin receptor signaling pathway
mlao04650  Natural killer cell mediated cytotoxicity
mlao04657  IL-17 signaling pathway
mlao04658  Th1 and Th2 cell differentiation
mlao04659  Th17 cell differentiation
mlao04660  T cell receptor signaling pathway
mlao04662  B cell receptor signaling pathway
mlao04664  Fc epsilon RI signaling pathway
mlao04666  Fc gamma R-mediated phagocytosis
mlao04668  TNF signaling pathway
mlao04713  Circadian entrainment
mlao04720  Long-term potentiation
mlao04722  Neurotrophin signaling pathway
mlao04723  Retrograde endocannabinoid signaling
mlao04724  Glutamatergic synapse
mlao04725  Cholinergic synapse
mlao04726  Serotonergic synapse
mlao04730  Long-term depression
mlao04810  Regulation of actin cytoskeleton
mlao04910  Insulin signaling pathway
mlao04912  GnRH signaling pathway
mlao04914  Progesterone-mediated oocyte maturation
mlao04915  Estrogen signaling pathway
mlao04916  Melanogenesis
mlao04917  Prolactin signaling pathway
mlao04919  Thyroid hormone signaling pathway
mlao04921  Oxytocin signaling pathway
mlao04926  Relaxin signaling pathway
mlao04928  Parathyroid hormone synthesis, secretion and action
mlao04929  GnRH secretion
mlao04930  Type II diabetes mellitus
mlao04933  AGE-RAGE signaling pathway in diabetic complications
mlao04934  Cushing syndrome
mlao04935  Growth hormone synthesis, secretion and action
mlao04960  Aldosterone-regulated sodium reabsorption
mlao05010  Alzheimer disease
mlao05020  Prion disease
mlao05022  Pathways of neurodegeneration - multiple diseases
mlao05034  Alcoholism
mlao05132  Salmonella infection
mlao05133  Pertussis
mlao05135  Yersinia infection
mlao05140  Leishmaniasis
mlao05142  Chagas disease
mlao05145  Toxoplasmosis
mlao05152  Tuberculosis
mlao05160  Hepatitis C
mlao05161  Hepatitis B
mlao05163  Human cytomegalovirus infection
mlao05164  Influenza A
mlao05165  Human papillomavirus infection
mlao05166  Human T-cell leukemia virus 1 infection
mlao05167  Kaposi sarcoma-associated herpesvirus infection
mlao05170  Human immunodeficiency virus 1 infection
mlao05171  Coronavirus disease - COVID-19
mlao05200  Pathways in cancer
mlao05203  Viral carcinogenesis
mlao05205  Proteoglycans in cancer
mlao05206  MicroRNAs in cancer
mlao05207  Chemical carcinogenesis - receptor activation
mlao05208  Chemical carcinogenesis - reactive oxygen species
mlao05210  Colorectal cancer
mlao05211  Renal cell carcinoma
mlao05212  Pancreatic cancer
mlao05213  Endometrial cancer
mlao05214  Glioma
mlao05215  Prostate cancer
mlao05216  Thyroid cancer
mlao05218  Melanoma
mlao05219  Bladder cancer
mlao05220  Chronic myeloid leukemia
mlao05221  Acute myeloid leukemia
mlao05223  Non-small cell lung cancer
mlao05224  Breast cancer
mlao05225  Hepatocellular carcinoma
mlao05226  Gastric cancer
mlao05230  Central carbon metabolism in cancer
mlao05231  Choline metabolism in cancer
mlao05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlao05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlao00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    141495705 (MAPK3)
   04012 ErbB signaling pathway
    141495705 (MAPK3)
   04014 Ras signaling pathway
    141495705 (MAPK3)
   04015 Rap1 signaling pathway
    141495705 (MAPK3)
   04350 TGF-beta signaling pathway
    141495705 (MAPK3)
   04370 VEGF signaling pathway
    141495705 (MAPK3)
   04371 Apelin signaling pathway
    141495705 (MAPK3)
   04668 TNF signaling pathway
    141495705 (MAPK3)
   04066 HIF-1 signaling pathway
    141495705 (MAPK3)
   04068 FoxO signaling pathway
    141495705 (MAPK3)
   04072 Phospholipase D signaling pathway
    141495705 (MAPK3)
   04071 Sphingolipid signaling pathway
    141495705 (MAPK3)
   04024 cAMP signaling pathway
    141495705 (MAPK3)
   04022 cGMP-PKG signaling pathway
    141495705 (MAPK3)
   04151 PI3K-Akt signaling pathway
    141495705 (MAPK3)
   04150 mTOR signaling pathway
    141495705 (MAPK3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    141495705 (MAPK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    141495705 (MAPK3)
   04148 Efferocytosis
    141495705 (MAPK3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    141495705 (MAPK3)
   04210 Apoptosis
    141495705 (MAPK3)
   04218 Cellular senescence
    141495705 (MAPK3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    141495705 (MAPK3)
   04520 Adherens junction
    141495705 (MAPK3)
   04540 Gap junction
    141495705 (MAPK3)
   04550 Signaling pathways regulating pluripotency of stem cells
    141495705 (MAPK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    141495705 (MAPK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    141495705 (MAPK3)
   04613 Neutrophil extracellular trap formation
    141495705 (MAPK3)
   04620 Toll-like receptor signaling pathway
    141495705 (MAPK3)
   04621 NOD-like receptor signaling pathway
    141495705 (MAPK3)
   04625 C-type lectin receptor signaling pathway
    141495705 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    141495705 (MAPK3)
   04660 T cell receptor signaling pathway
    141495705 (MAPK3)
   04658 Th1 and Th2 cell differentiation
    141495705 (MAPK3)
   04659 Th17 cell differentiation
    141495705 (MAPK3)
   04657 IL-17 signaling pathway
    141495705 (MAPK3)
   04662 B cell receptor signaling pathway
    141495705 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    141495705 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    141495705 (MAPK3)
   04062 Chemokine signaling pathway
    141495705 (MAPK3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    141495705 (MAPK3)
   04929 GnRH secretion
    141495705 (MAPK3)
   04912 GnRH signaling pathway
    141495705 (MAPK3)
   04915 Estrogen signaling pathway
    141495705 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    141495705 (MAPK3)
   04917 Prolactin signaling pathway
    141495705 (MAPK3)
   04921 Oxytocin signaling pathway
    141495705 (MAPK3)
   04926 Relaxin signaling pathway
    141495705 (MAPK3)
   04935 Growth hormone synthesis, secretion and action
    141495705 (MAPK3)
   04919 Thyroid hormone signaling pathway
    141495705 (MAPK3)
   04928 Parathyroid hormone synthesis, secretion and action
    141495705 (MAPK3)
   04916 Melanogenesis
    141495705 (MAPK3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141495705 (MAPK3)
   04270 Vascular smooth muscle contraction
    141495705 (MAPK3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    141495705 (MAPK3)
  09156 Nervous system
   04724 Glutamatergic synapse
    141495705 (MAPK3)
   04725 Cholinergic synapse
    141495705 (MAPK3)
   04726 Serotonergic synapse
    141495705 (MAPK3)
   04720 Long-term potentiation
    141495705 (MAPK3)
   04730 Long-term depression
    141495705 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    141495705 (MAPK3)
   04722 Neurotrophin signaling pathway
    141495705 (MAPK3)
  09158 Development and regeneration
   04360 Axon guidance
    141495705 (MAPK3)
   04380 Osteoclast differentiation
    141495705 (MAPK3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    141495705 (MAPK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    141495705 (MAPK3)
   05206 MicroRNAs in cancer
    141495705 (MAPK3)
   05205 Proteoglycans in cancer
    141495705 (MAPK3)
   05207 Chemical carcinogenesis - receptor activation
    141495705 (MAPK3)
   05208 Chemical carcinogenesis - reactive oxygen species
    141495705 (MAPK3)
   05203 Viral carcinogenesis
    141495705 (MAPK3)
   05230 Central carbon metabolism in cancer
    141495705 (MAPK3)
   05231 Choline metabolism in cancer
    141495705 (MAPK3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    141495705 (MAPK3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    141495705 (MAPK3)
   05212 Pancreatic cancer
    141495705 (MAPK3)
   05225 Hepatocellular carcinoma
    141495705 (MAPK3)
   05226 Gastric cancer
    141495705 (MAPK3)
   05214 Glioma
    141495705 (MAPK3)
   05216 Thyroid cancer
    141495705 (MAPK3)
   05221 Acute myeloid leukemia
    141495705 (MAPK3)
   05220 Chronic myeloid leukemia
    141495705 (MAPK3)
   05218 Melanoma
    141495705 (MAPK3)
   05211 Renal cell carcinoma
    141495705 (MAPK3)
   05219 Bladder cancer
    141495705 (MAPK3)
   05215 Prostate cancer
    141495705 (MAPK3)
   05213 Endometrial cancer
    141495705 (MAPK3)
   05224 Breast cancer
    141495705 (MAPK3)
   05223 Non-small cell lung cancer
    141495705 (MAPK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    141495705 (MAPK3)
   05170 Human immunodeficiency virus 1 infection
    141495705 (MAPK3)
   05161 Hepatitis B
    141495705 (MAPK3)
   05160 Hepatitis C
    141495705 (MAPK3)
   05171 Coronavirus disease - COVID-19
    141495705 (MAPK3)
   05164 Influenza A
    141495705 (MAPK3)
   05163 Human cytomegalovirus infection
    141495705 (MAPK3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    141495705 (MAPK3)
   05165 Human papillomavirus infection
    141495705 (MAPK3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    141495705 (MAPK3)
   05135 Yersinia infection
    141495705 (MAPK3)
   05133 Pertussis
    141495705 (MAPK3)
   05152 Tuberculosis
    141495705 (MAPK3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    141495705 (MAPK3)
   05140 Leishmaniasis
    141495705 (MAPK3)
   05142 Chagas disease
    141495705 (MAPK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    141495705 (MAPK3)
   05020 Prion disease
    141495705 (MAPK3)
   05022 Pathways of neurodegeneration - multiple diseases
    141495705 (MAPK3)
  09165 Substance dependence
   05034 Alcoholism
    141495705 (MAPK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    141495705 (MAPK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    141495705 (MAPK3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    141495705 (MAPK3)
   04934 Cushing syndrome
    141495705 (MAPK3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    141495705 (MAPK3)
   01524 Platinum drug resistance
    141495705 (MAPK3)
   01522 Endocrine resistance
    141495705 (MAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlao01001]
    141495705 (MAPK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mlao03036]
    141495705 (MAPK3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mlao04147]
    141495705 (MAPK3)
Enzymes [BR:mlao01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     141495705 (MAPK3)
Protein kinases [BR:mlao01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   141495705 (MAPK3)
Chromosome and associated proteins [BR:mlao03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     141495705 (MAPK3)
Exosome [BR:mlao04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   141495705 (MAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 141495705
NCBI-ProteinID: XP_074053426
LinkDB
Position
8:complement(60839482..60847114)
AA seq 380 aa
MAAAVAAEGGGGGEPRGLDGPGAGVAGRVEMVKGQPFDVGPRYTELQYIGEGAYGMVSSA
FDHVRKARVAIKKISPFEHQTYCQRTLREIQILLRCHHENVIGIRDILRAPTLEAMRDVY
IVQDLMETDLYKLLKSQQLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCD
LKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML
SNRPIFPGKHYLDQLNHILGILGSPSQDDLNCIINMKARNYLQSLPSKTKVPWVKLFPKA
DPKALDLLDRMLTFNPNKRITVEDALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKER
LKELIFQETARFQPGAPGAP
NT seq 1143 nt   +upstreamnt  +downstreamnt
atggcggcggcggtggcggctgaggggggagggggcggggagccccgggggctcgacggg
ccgggcgcgggggtcgcgggcagagtggagatggtgaagggccagccgttcgacgtcggg
ccgcgctacacagaactgcagtacattggggaaggggcgtacggcatggtcagctctgcc
tttgaccatgtgcggaaggcccgggtagccatcaaaaaaatcagcccgtttgagcaccag
acatattgccaacgcacccttcgggagattcagatcctgcttcgttgccaccatgaaaat
gtcattggcatccgagacatccttcgagcacccactctggaggccatgagagatgtctat
attgttcaggacctgatggaaacagacttgtataaactgctcaagagccagcagctgagt
aatgaccatgtctgctacttcctgtaccaaatcctacggggtctcaaatacatccactct
gccaatgtgctccatcgggacctcaaaccttccaacttgctcattaacaccacttgtgac
ctcaagatctgtgactttggtctggcccgaattgctgaccctgagcatgatcacacaggc
ttcctgacagagtatgtggctacccgctggtatagagcaccagagatcatgctcaattcc
aagggctataccaaatccatcgatatttggtctgtgggctgtatcctcgcagaaatgctc
tccaatcgacccatctttcctgggaagcattacctggaccagctgaaccatattctaggt
atcctgggttctccatctcaggatgatctgaactgtatcatcaacatgaaggctcggaat
tatctgcagtcccttccatccaagacgaaggtgccctgggtcaagctgtttcccaaagca
gaccccaaagctctggacctgctagaccggatgttgacctttaaccccaacaagcgaatc
acagtggaggatgccctggcccacccctacttggagcagtactatgatccaactgatgag
ccagtggcagaagaaccttttacctttgacatggagttggatgacctgccaaaggaacga
ctgaaggaactcatcttccaagagacagcccgattccaacctggagctccaggagcaccc
tga

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