Macrotis lagotis (bilby): 141497422
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Entry
141497422 CDS
T11097
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X1
KO
K12385
Niemann-Pick C1 protein
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
mlao04142
Lysosome
mlao04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
141497422
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
141497422
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
141497422
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
mlao02000
]
141497422
Transporters [BR:
mlao02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
141497422
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
141497422
NCBI-ProteinID:
XP_074056171
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Position
X:453039702..453099638
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AA seq
1298 aa
AA seq
DB search
MRTPRPRPGLLLAAGLALLLPVQVFSQSCIWYGECGEASEGKRFNCEYSGPPKPLPKDGY
DLVQELCPGFFFDNVSLCCDVQQLQTLKNNLQLPLQFLSRCPSCFYNLLNLFCELTCSPR
QSQFLNVTSTSNYTDPVTNETKINVEELQYYIGQNFANAMYNACRDVEAPSSNDKALGLL
CGKDAKDCNATNWIQYMFDKDNGQAPFTITPIFSDIRIYGMEPMKNATKGCNESVDDATG
PCSCQDCSITCGPKPQPPPPPAPWLILGLDAMYVIMWIFYMGFLLVFFGMFFIIWCYRKR
YFVSEYTPIDGNIAFSVNASDRGMAWLLTSNLPSSHALPGEASCCDQLGAKFESCLTQGF
TQWGSFCVRNPVPVIFCSLIVIAVCCSGLVFMKLTTNPVDLWSAPNSQAHLEKEYFDTHF
GPFFRTEQLIIRAPNTSQHTYQPYPSGSDVPFGPPLDKEILHQVLDLQTAIEQITASYNN
ETVTLQDICLAPLSPYNNNCTILSVLNYFQNSHSVLDHEKGDDFYVYADYHTHFLYCTRA
PASLNDTSVLHDSCLGTFGGPVFPWLVLGGYDEQNYNNATALVITLPVNNYYNNTEKLQR
AQAWEKEFISFVKNYKNPNLTISFSAERSIEDEINRESNGDVVTVLISYAVMFLYISMAL
GHIRSCRRFLVDSKISLGIAGILMVLSSVVCSLGLFSYVGIPLTLIVIEVIPFLVLAVGV
DNIFILVQTFQRDERLQGETVDKQLGRILGEVAPSMFLSSFSETVAFFLGALSPMPAVRT
FSLFAGMAVFIDFLLQITCFVSLLGLDIKRQEKNKLDVLCCIRIAEDRTSPQLSESYLFR
FFKNVFSPFLLKDWMRPIVISVFVGILSFSIAVLNKVEIGLDQSLSMPDDSYVLDYFKSL
NQYLHAGPPVYFVLEEGHDYTSLKGQNMVCGGMGCNNNSLVQQIFNAAELQNYTKIGFAP
SSWIDDYFDWIKPQSSCCRIYNMTDQFCNASVVDPSCIRCRPLTPEGKRRPQGKDFMKFL
PMFLSDNPNPKCGKGGHASYSSGVIIKNSSTEVGATYFMTYHTVLHTSSDYIDAMRKARM
VATNITESMGLQDKNYRVFPYSIFYVFYEQYLTIVGDTIFNLGISLGAIFLVTAILLGCD
LWSAVIMCVTIAMILVNMFGVMWLWDISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTK
GSRVARAEEALSHMGSCVFSGITLTKFGGIVVLAFARSQIFQIFYFRMYLAMVLLGATHG
LIFLPVLLSYLGPSINKAKSHAAQERNRGTERERLLNF
NT seq
3897 nt
NT seq
+upstream
nt +downstream
nt
atgaggacgccgcgcccccggcccgggctgctgctggcggccggcctggcgctgctgctg
ccggtgcaggtattttcacagtcctgtatttggtatggagagtgtggtgaggcctctgaa
ggtaagagattcaactgtgaatattcagggccaccaaaaccattgccaaaggatggatat
gacttagtgcaggaactctgtccaggcttcttctttgacaatgtcagtctttgttgtgac
gtacagcaacttcagacactgaaaaataatttgcagttgcctctacagtttctatccagg
tgtccatcttgtttttacaacctattgaacctgttttgtgagctaacttgcagccctcga
caaagtcagtttctgaatgttacaagtaccagtaactatactgatcctgtcacaaatgag
actaaaataaatgtcgaagaactacagtactacattggacagaactttgccaatgccatg
tataatgcctgccgggatgttgaggccccctcaagtaatgataaagcactggggcttctg
tgtgggaaagatgctaaagactgcaatgctaccaattggatccaatacatgttcgataaa
gataatggacaagcacctttcaccatcacgcctattttttcagatattcgtatttatggg
atggaaccaatgaaaaatgccactaaaggttgtaatgaatcagtggatgatgcaactggg
ccttgtagctgtcaggattgttccattacttgtggtcctaaaccccagcccccacctcct
cctgctccttggctgatacttggcttggatgccatgtatgtcattatgtggatcttctac
atgggattcttgcttgtattttttggaatgttttttataatatggtgctatagaaaacga
tattttgtttctgagtacacacctattgatggcaatatagccttttctgttaatgccagt
gatcgaggaatggcttggctcttaacctccaacctcccttcctctcatgctcttccaggg
gaggcctcctgttgtgatcaacttggtgcaaaatttgagagctgtttgacacaagggttt
acacaatgggggtctttctgtgttagaaacccagtgcctgtcatcttctgttccctgatc
gtcattgcggtgtgctgttcgggtctggtgttcatgaagctcacaaccaatccagttgat
ctttggtctgcccctaatagccaagctcatctagagaaagaatactttgatacccacttt
ggacctttcttccgtactgaacagcttataatccgggctccaaatactagccagcacact
taccagccatatccttctggatcagatgttccctttgggccccctctggacaaagagatc
ctgcaccaggtcctagacttacagacagccatcgagcaaattactgcttcttataacaat
gaaacagtgactcttcaggacatctgtttggcccccttgtctccttacaacaacaactgt
accattttgagtgtattaaattacttccagaatagccattctgttttggaccatgaaaaa
ggagacgatttctatgtctatgcagactatcacacccacttcttatactgcacacgggct
cctgcctctctgaatgatacaagtgtgcttcatgattcttgtttgggaacttttggaggg
cctgttttcccttggcttgtcttaggaggttatgatgagcaaaactataataatgctact
gctcttgtgattactcttcctgtcaataattactacaacaacactgaaaagctgcaaaga
gcccaagcctgggaaaaagaattcatcagctttgtaaaaaactacaaaaatccaaacctg
actatttctttctctgctgagcgaagtattgaagatgagataaatcgtgaaagtaatggt
gatgttgtcactgttctaattagctatgctgtcatgtttttatatatttccatggcctta
ggacatatcagaagttgtcgtagattcctggtagattccaaaatctccctgggtattgca
ggtatcctgatggtgcttagttcagtagtgtgttctctaggtctcttcagctacgttgga
attcccctcaccttgattgtcattgaagtcatcccattcctggtgcttgcagttggagta
gacaatatttttattctagttcagacttttcagagagatgaacgtcttcaaggggaaaca
gtggataaacaactgggcaggatcctgggggaagtggctccaagcatgttcctgtcatca
ttttcagagactgtagcctttttcttaggggctttgtcacccatgccagctgttcgaacc
ttttctctgtttgctggaatggctgttttcattgactttctccttcaaattacttgtttt
gtgagtctcttgggcctggacattaagcgtcaagagaaaaataaattggacgttttgtgt
tgcatcagaattgctgaagacagaaccagcccccaattatcagagagttatttgtttcgg
tttttcaaaaatgtcttctctccatttctgctgaaggactggatgcgaccaattgtgata
tctgtatttgtgggcattctgtcattcagcatagcagttctcaacaaagtggaaattggc
ttggatcagtctctttcaatgccagatgactcttatgtactagattatttcaagtccttg
aaccagtacttacatgcaggtcctcctgtgtattttgtgctagaagaaggacatgactat
acctctctaaaaggacagaacatggtgtgtggtggaatgggatgtaacaacaattcactt
gtgcagcagatctttaatgctgcagaactacagaattacacaaaaataggttttgccccc
tcttcctggattgatgattattttgactggattaaacctcagtcttcctgctgtcggatt
tataatatgacagaccagttttgtaatgcttcagttgttgacccttcctgtattcgttgt
cgacctttgactccagagggtaaaaggaggccacagggcaaagacttcatgaaatttcta
cctatgtttctttctgacaacccaaatcctaaatgtggcaaaggggggcatgcatcttat
agttctggcgtaatcatcaaaaacagttccactgaggttggagccacgtactttatgact
tatcatactgtgcttcatacttcctctgactatattgatgccatgagaaaagcaaggatg
gtggccactaacatcactgaaagcatgggtctccaagacaaaaactaccgagtatttcca
tatagtatattttacgtcttctatgagcaatacctgaccatagtgggtgacacaatcttt
aaccttggtatatccctgggagcaatattcttggtgactgcaatactcctaggctgtgat
ctgtggtctgctgtgatcatgtgtgttacaattgctatgattttggtcaacatgtttgga
gttatgtggctctgggacatttctctgaatgctgtttccttggtcaacttggtaatgagt
tgtggtatctctgtggagttctgtagtcatatcaccagagcctttacagtgagcacaaag
ggtagtcgggttgcacgtgccgaggaggccctatcccacatgggcagttgtgttttcagt
ggaattacactaacaaaatttggagggattgtggtgttggcctttgccagatctcaaatt
ttccagatattttactttcggatgtatttagctatggtcttgttgggagcaactcatggc
ttaatattccttccagtcttacttagttatttagggccatcaataaataaagctaaaagt
catgctgctcaagaacgaaacagaggcactgaacgagaacggctcctcaacttctag
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