Macrotis lagotis (bilby): 141500283
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Entry
141500283 CDS
T11097
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao04217
Necroptosis
mlao04380
Osteoclast differentiation
mlao04620
Toll-like receptor signaling pathway
mlao04621
NOD-like receptor signaling pathway
mlao04630
JAK-STAT signaling pathway
mlao04658
Th1 and Th2 cell differentiation
mlao04659
Th17 cell differentiation
mlao05145
Toxoplasmosis
mlao05160
Hepatitis C
mlao05161
Hepatitis B
mlao05162
Measles
mlao05164
Influenza A
mlao05165
Human papillomavirus infection
mlao05167
Kaposi sarcoma-associated herpesvirus infection
mlao05168
Herpes simplex virus 1 infection
mlao05169
Epstein-Barr virus infection
mlao05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
141500283 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
141500283 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
141500283 (TYK2)
04621 NOD-like receptor signaling pathway
141500283 (TYK2)
04658 Th1 and Th2 cell differentiation
141500283 (TYK2)
04659 Th17 cell differentiation
141500283 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
141500283 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
141500283 (TYK2)
05160 Hepatitis C
141500283 (TYK2)
05171 Coronavirus disease - COVID-19
141500283 (TYK2)
05164 Influenza A
141500283 (TYK2)
05162 Measles
141500283 (TYK2)
05168 Herpes simplex virus 1 infection
141500283 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
141500283 (TYK2)
05169 Epstein-Barr virus infection
141500283 (TYK2)
05165 Human papillomavirus infection
141500283 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
141500283 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlao01001
]
141500283 (TYK2)
Enzymes [BR:
mlao01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
141500283 (TYK2)
Protein kinases [BR:
mlao01001
]
Non-receptor tyrosine kinases
JAK family [OT]
141500283 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
141500283
NCBI-ProteinID:
XP_074059459
LinkDB
All DBs
Position
X:complement(625228179..625243628)
Genome browser
AA seq
1197 aa
AA seq
DB search
MPLCHCAARHSDSDGDWGHPSSSGLKVLLHWSNGGDQYVTYNQGTMTAEEICIHIAQKVG
IAPLCYNLFALYDTQAQIWLPPNHLFEITKDTNQILQFRMRYYFRNWHGQNAQEPAVYRS
MPRGVEVSEEKPRIEQESALLDKASFEYLYEQGKFEFVNDVASLSDLHSETEIHHFKNES
LGMAVLHLSHLALQRGVPLEEVVRKTSFKDCIPRSFSRQIQQNNSLTKFRLRNVFQKFMR
RFHLQTVGLGRLSEQDIMFKYLATLEQLAPRFGTERFLALTLALPTEAERDRCYVNSSEQ
GPAIPPGSTLSLADQAPTHEVLVTGTNGIHWRLLQVEDSDLEINHSRSSFGKKSKAREAE
SRKLSQLPTERKESPWTYFCDFQDITHVVVKENNVSIHRQDNKCLELTLPSPMVALSLVS
LVDGYFRLTADSSHYLCHEVAPPRLVMSIQNGIHGPLQESYVLSKLKREEVEDGLYLIRW
SSFDFHRLILTVARKDQASGTQGLCYKQFRIEERGLTFQLEGWDQAFPSVRELTAALQGC
TLRSSSGSGPGSSLESFTLSKCCLPRAGEISNLIITRQRPKESLKPLNLSQLSFHQIRKE
EIKQLAHLGQGTRTNIYEGLLHVGGGMGTEDEEEENILSEPNNNDRELRVVLKVLDPSHR
DIALAFFETASLMSQVSHIHLAFVHGVCVRGSENIMVAEHVEHGPLDVCLRREKGHVPVA
WKITVAQQLASALSYLEDKNLVHGNVCAKNILLARRGLGDGTQPFIKLSDPGVSVTALSK
EERVERIPWIAPECVTSGTGLSTAADKWSFGTTLLEICFDGEAPLQGRTPSEKERFYEKK
HRLPEPSCKELANLISQCLTYEVNQRPSFRTILRDLTQLQPQNLVDITTMSPEFPASDPT
VFQKRYLKKIRDLGEGHFGKVSLYCYDPNNDGTGEMVAVKSLKAGCSSQLLSSWQREIEI
LRTLYHEHIVKYKGCCSDQGEKMVQLIMEYVPLGSLRDYLPKHSLGLAQILLFAQQICEG
MAYLHSQHYIHRDLAARNVLLENDNTVKIGDFGLAKAVPEGHDYYCVQEDGDSPVFWYAM
ECLKECKFYYASDVWSFGVTLYELLTRCDCNQTPPLKFIEMIGVTQGQMTVLRLIDLLEK
GQRLPCPKDCPCEIYLLMKNCWESEASFRPTFQNLIPLLRTFHEKYRSQAPSVFSVC
NT seq
3594 nt
NT seq
+upstream
nt +downstream
nt
atgccactatgtcactgtgctgcaagacacagtgactctgatggagactggggccaccct
agcagcagtggactcaaagttctccttcactggagcaatggcggtgaccagtatgtgacc
tacaaccagggtaccatgactgcagaggaaatctgcattcacattgcacagaaagtgggg
attgctccactttgctacaatctttttgcattatatgatacccaggcccaaatttggctg
cctcctaaccacctctttgagatcaccaaggacaccaaccaaatactgcagtttcggatg
aggtattacttccgaaactggcatggccagaatgcccaggagccagctgtgtaccgaagc
atgcctagaggtgttgaggtctctgaagagaagccccggattgagcaggagtctgctttg
ctggacaaagcttccttcgagtacctctatgaacaggggaagtttgagtttgtcaatgat
gttgcatcgctttcggacctacatagtgaaacagagatacatcacttcaagaatgagagc
ctcggcatggccgtgctgcatctttcccaccttgccctacagcgtggtgtccccctggaa
gaggtggtgaggaagaccagcttcaaagactgcatcccgcgttccttcagccgacaaatc
cagcagaacaactccctgaccaaattccgcctgaggaatgtcttccagaagtttatgcga
cgtttccatctacagacagtgggtctagggcgtcttagtgaacaggacattatgttcaaa
tacctggctacactggagcaactggccccacgctttggcactgagcgttttcttgccctg
accttggcattgcccactgaggctgaaagggatcgatgctatgtcaatagcagtgagcaa
gggcctgccatcccaccgggatccactctctcccttgctgaccaggctcctacccatgag
gttctcgtgacgggtacaaatggtatccattggcggcttcttcaggtggaggactctgac
ttggaaatcaaccattcccgaagttcctttggtaaaaagtccaaggcccgggaggcagaa
agccggaagctgagccagctgcctactgagagaaaagagagcccatggacctatttttgt
gacttccaagatatcactcatgttgtagtcaaggagaacaacgtcagcatccaccgtcag
gacaacaagtgcctggaactgactctcccttcacctatggtggcactctctctggtatcc
ctggtggatggctatttcagactgacagcagactccagccactacctgtgccatgaggtg
gcccccccaaggctggtgatgagcattcaaaatggcatccatgggcccctgcaggaatct
tatgtgctgtccaaactgaagcgagaggaggtagaagatggactctaccttatccgctgg
agttcctttgacttccatcgcctcatcctgactgtggcccgaaaggatcaggcatctgga
acacagggtctctgttacaagcagttccgtattgaagagcgaggtctgaccttccagctg
gaaggctgggatcaagcatttcccagtgtgcgtgagcttactgcagccctgcaaggctgc
acactgagatccagctccggctctggtcctggctccagcctagaaagcttcacactcagc
aaatgttgcctgcctcgagcaggagaaatttccaacctgatcattaccaggcagcgtcct
aaggagagcctcaaaccactcaacttgtcccaactcagcttccaccagatccgaaaggaa
gagatcaaacagctggctcacctgggtcagggcacccggaccaatatttatgagggactc
ctgcatgtgggaggtggaatgggaactgaagatgaagaagaggagaacattctctcagag
cccaataacaacgatcgggagcttcgagttgtgctgaaggtgctggacccaagtcaccgt
gatattgctctggcattttttgagacagccagcttaatgagccaggtctctcatattcac
ttggcctttgtacatggtgtttgtgtccggggctctgagaacatcatggtggcagaacat
gtagaacatggaccactggatgtatgtcttcgccgggagaagggccatgtgcctgtggcc
tggaagattactgtggcccagcagctcgccagtgctctcagctacctagaggataagaac
ctggttcatggtaatgtctgtgccaagaacatcttgctggcaaggcgtggccttggagat
ggtacccagcctttcatcaagctcagtgatcctggagtcagtgtcactgccctctccaag
gaagagagagtagagcgcattccctggattgctcccgagtgtgtcaccagtgggactggc
ctcagcacagctgctgacaagtggagctttggaacgacactattagagatctgctttgat
ggggaagcacctctacagggtcgtaccccttccgagaaggagcgcttttatgagaagaaa
caccggctccctgagccttcatgcaaggagctggccaatctcatcagccagtgcctcacc
tatgaggtcaatcagcgaccatcctttagaaccatcctccgtgatctcacccaactgcag
ccccaaaatcttgttgatatcaccaccatgagcccagagttcccagcctcagacccaact
gtttttcagaaacgttacctaaagaagatccgagacctgggagagggtcactttggcaag
gtgagcctctactgctatgacccaaataatgatgggacaggtgagatggtggctgtgaaa
tctctcaaggctggctgcagttcccaacttctgagcagctggcaacgggagatcgagatc
cttcggacactctaccacgagcacattgtcaagtataagggctgctgtagtgaccaaggg
gagaagatggtacagctgatcatggaatacgtgccactaggcagcttacgggactacctc
cccaaacacagtttgggactggcccagattctgttgtttgctcagcagatctgtgagggc
atggcttacctccattcccaacactacatccaccgagacctggcagcccgaaatgtcctt
ctagagaatgacaacactgtcaagattggggactttggcctggccaaggcggttccagaa
ggccatgattactactgtgtccaggaggatggagatagccctgtcttctggtatgccatg
gagtgtcttaaggaatgtaagttctactatgcctcagatgtctggtcctttggggtcacc
ctctatgagctgctgactcgttgtgactgcaatcaaaccccccccttgaaattcatcgaa
atgattggggtcacccagggccagatgacagtgctgaggctcattgatctgttagaaaaa
ggtcagagactgccttgtcccaaggactgtccctgtgagatctatcttctcatgaagaat
tgctgggaatctgaagcctcctttcgcccgaccttccagaaccttatccccctcctcagg
acattccatgagaagtacagaagtcaggcaccctctgtgtttagtgtgtgctga
DBGET
integrated database retrieval system
